Search Results - "Grubisha, M J"

MAP2 is differentially phosphorylated in schizophrenia, altering its function by Grubisha, M. J., Sun, X., MacDonald, M. L., Garver, M., Sun, Z., Paris, K. A., Patel, D. S., DeGiosio, R. A., Lewis, D. A., Yates, N. A., Camacho, C., Homanics, G. E., Ding, Y., Sweet, R. A.

“…Schizophrenia (Sz) is a highly polygenic disorder, with common, rare, and structural variants each contributing only a small fraction of overall disease risk…”
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Differential regulation of MAP2 by phosphorylation events in proline‐rich versus C‐terminal domains by DeGiosio, R. A., Needham, P. G., Andrews, O. A., Tristan, H., Grubisha, M. J., Brodsky, J. L., Camacho, C., Sweet, R. A.

“…MAP2 is a critical cytoskeletal regulator in neurons. The phosphorylation of MAP2 (MAP2‐P) is well known to regulate core functions of MAP2, including…”
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Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling by Wheeler, D S, Barrick, S R, Grubisha, M J, Brufsky, A M, Friedman, P A, Romero, G

“…Although Wnt-Frizzled (Fzd) signaling is critical in the pathophysiology of carcinomas, its role in human breast cancer has been difficult to establish. We…”
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Trio and Kalirin as unique enactors of Rho/Rac spatiotemporal precision by Grubisha, M.J., DeGiosio, R.A., Wills, Z.P., Sweet, R.A.

“…Rac1 and RhoA are among the most widely studied small GTPases. The classic dogma surrounding their biology has largely focused on their activity as an “on/off…”
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Deciphering the alteration of MAP2 interactome caused by a schizophrenia-associated phosphorylation by Lyu, J., MacDonald, M.L., Ruiz, S., Chou, S., Gilardi, J., Buchwald, S.C., Grubisha, M.J., Sweet, R.A.

“…Microtubule-associated protein 2 (MAP2) is a crucial regulator of dendritic structure and neuronal function, orchestrating diverse protein interactions within…”
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Direct interaction between NHERF1 and Frizzled regulates [beta]-catenin signaling by Wheeler, D S, Barrick, S R, Grubisha, M J, Brufsky, A M, Friedman, P A, Romero, G

“…Although Wnt-Frizzled (Fzd) signaling is critical in the pathophysiology of carcinomas, its role in human breast cancer has been difficult to establish. We…”
Get full text