Search Results - "Gruber, Peter J"
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Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency
Published in Cell stem cell (08-04-2011)“…Transcription factor-based cellular reprogramming has opened the way to converting somatic cells to a pluripotent state, but has faced limitations resulting…”
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2
Amnion signals are essential for mesoderm formation in primates
Published in Nature communications (26-08-2021)“…Embryonic development is largely conserved among mammals. However, certain genes show divergent functions. By generating a transcriptional atlas containing…”
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3
Transplantation-Free Survival and Interventions at 3 Years in the Single Ventricle Reconstruction Trial
Published in Circulation (New York, N.Y.) (20-05-2014)“…BACKGROUND—In the Single Ventricle Reconstruction (SVR) trial, 1-year transplantation-free survival was better for the Norwood procedure with right…”
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4
Is a hybrid strategy a lower-risk alternative to stage 1 Norwood operation?
Published in The Journal of thoracic and cardiovascular surgery (01-01-2017)“…Abstract Background For neonates with critical left ventricular outflow tract obstruction (LVOTO), hybrid procedures are an alternative to the Norwood stage 1…”
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5
Cumulative Exposure to Medical Radiation for Children Requiring Surgery for Congenital Heart Disease
Published in The Journal of pediatrics (01-04-2014)“…Objective To describe cumulative radiation exposure in a large single-center cohort of children with congenital heart disease (CHD) and identify risk factors…”
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6
Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice
Published in The FASEB journal (01-10-2008)“…Limitation of infarct size is a major goal of therapy for acute coronary syndromes, and research has focused on achieving rapid patency of infarct-related…”
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7
Contemporary outcomes of surgical ventricular septal defect closure
Published in The Journal of thoracic and cardiovascular surgery (01-03-2013)“…Objectives Surgical closure of ventricular septal defects remains the most common pediatric cardiac surgical procedure. No studies, however, have…”
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8
Association of Pulmonary Conduit Type and Size With Durability in Infants and Young Children
Published in The Annals of thoracic surgery (01-11-2013)“…Background Treatment of congenital heart disease may include placement of a right ventricle to pulmonary artery conduit that requires future surgical…”
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9
Shared Segment Analysis and Next-Generation Sequencing Implicates the Retinoic Acid Signaling Pathway in Total Anomalous Pulmonary Venous Return (TAPVR)
Published in PloS one (29-06-2015)“…Most isolated congenital heart defects are thought to be sporadic and are often ascribed to multifactorial mechanisms with poorly understood genetics. Total…”
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10
Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects
Published in The Annals of thoracic surgery (01-06-2002)“…Background. A novel therapeutic option for the treatment of acute myocardial infarction involves the use of mesenchymal stem cells (MSCs). The purpose of this…”
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11
Gata4 and Gata5 Cooperatively Regulate Cardiac Myocyte Proliferation in Mice
Published in The Journal of biological chemistry (15-01-2010)“…GATA5 is a member of the zinc finger transcription factor GATA family (GATA1–6) that plays a wide variety of roles in embryonic and adult development…”
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12
Fibrosis in Fontan Physiology
Published in The Journal of thoracic and cardiovascular surgery (01-06-2016)Get full text
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13
Technical performance score is associated with outcomes after the Norwood procedure
Published in The Journal of thoracic and cardiovascular surgery (01-11-2014)“…Objectives The technical performance score (TPS) has been reported in a single center study to predict the outcomes after congenital cardiac surgery. We sought…”
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14
Common variation in ISL1 confers genetic susceptibility for human congenital heart disease
Published in PloS one (26-05-2010)“…Congenital heart disease (CHD) is the most common birth abnormality and the etiology is unknown in the overwhelming majority of cases. ISLET1 (ISL1) is a…”
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15
Surgical management of competing pulmonary blood flow affects survival before Fontan/Kreutzer completion in patients with tricuspid atresia type I
Published in The Journal of thoracic and cardiovascular surgery (01-11-2015)“…Abstract Objectives To determine the association between surgical management of pulmonary blood flow (PBF) at initial and staged procedures with survival to…”
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16
Sequencing of a Chinese tetralogy of Fallot cohort reveals clustering mutations in myogenic heart progenitors
Published in JCI insight (25-01-2022)“…Tetralogy of Fallot (TOF) is the most common cyanotic heart defect, yet the underlying genetic mechanisms remain poorly understood. Here, we performed…”
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17
Genetic association studies: Is non-replication failure or progress?
Published in The Journal of thoracic and cardiovascular surgery (01-06-2019)Get full text
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18
Repair of Traumatic Aortoinnominate Disruption Using CorMatrix
Published in The Annals of thoracic surgery (01-04-2013)“…Blunt traumatic injuries to the innominate artery are rare but potentially devastating injuries. Patients with an innominate injury who survive typically have…”
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Coronary Ostioplasty for Congenital Atresia of the Left Main Coronary Artery Ostium
Published in The Annals of thoracic surgery (01-10-2012)“…Background Coronary ostial atresia is a rare anomaly, most frequently managed with coronary artery bypass grafting. This condition is often misdiagnosed as…”
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20
Diaphragm plication: When and why to do it
Published in The Journal of thoracic and cardiovascular surgery (01-11-2017)Get full text
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