Search Results - "Gruber, Conor N"

Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C) by Gruber, Conor N., Patel, Roosheel S., Trachtman, Rebecca, Lepow, Lauren, Amanat, Fatima, Krammer, Florian, Wilson, Karen M., Onel, Kenan, Geanon, Daniel, Tuballes, Kevin, Patel, Manishkumar, Mouskas, Konstantinos, O’Donnell, Timothy, Merritt, Elliot, Simons, Nicole W., Barcessat, Vanessa, Del Valle, Diane M., Udondem, Samantha, Kang, Gurpawan, Agashe, Charuta, Karekar, Neha, Grabowska, Joanna, Nie, Kai, Le Berichel, Jessica, Xie, Hui, Beckmann, Noam, Gangadharan, Sandeep, Ofori-Amanfo, George, Laserson, Uri, Rahman, Adeeb, Kim-Schulze, Seunghee, Charney, Alexander W., Gnjatic, Sacha, Gelb, Bruce D., Merad, Miriam, Bogunovic, Dusan

“…Initially, children were thought to be spared from disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, a month into the…”
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Acquired chemoresistance drives spatial heterogeneity, chemoprotection and collective migration in pancreatic tumor spheroids by Thege, Fredrik I, Cardle, Ian I, Gruber, Conor N, Siemann, Megan J, Cong, Sophie, Wittmann, Katharina, Love, Justin, Kirby, Brian J

“…Tumors display rich cellular heterogeneity and typically consist of multiple co-existing clones with distinct genotypic and phenotypic characteristics. The…”
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A Case of Methimazole-Induced Chronic Arthritis Masquerading as Seronegative Rheumatoid Arthritis by Gruber, Conor N, Finzel, Kathleen, Gruber, Barry L

“…ABSTRACTWe report a 40-year-old woman with onset of oligoarthritis shortly after initiating treatment with methimazole for Graves disease. Over the course of 7…”
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Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function by Gruber, Conor N., Calis, Jorg J.A., Buta, Sofija, Evrony, Gilad, Martin, Jerome C., Uhl, Skyler A., Caron, Rachel, Jarchin, Lauren, Dunkin, David, Phelps, Robert, Webb, Bryn D., Saland, Jeffrey M., Merad, Miriam, Orange, Jordan S., Mace, Emily M., Rosenberg, Brad R., Gelb, Bruce D., Bogunovic, Dusan

“…Autoinflammatory disease can result from monogenic errors of immunity. We describe a patient with early-onset multi-organ immune dysregulation resulting from a…”
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Type I IFN is siloed in endosomes by Altman, Jennie B., Taft, Justin, Wedeking, Tim, Gruber, Conor N., Holtmannspötter, Michael, Piehler, Jacob, Bogunovic, Dusan

“…Type I IFN (IFN-I) is thought to be rapidly internalized and degraded following binding to its receptor and initiation of signaling. However, many studies…”
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Randomized, Noncomparative, Phase II Trial of Early Switch From Docetaxel to Cabazitaxel or Vice Versa, With Integrated Biomarker Analysis, in Men With Chemotherapy-Naïve, Metastatic, Castration-Resistant Prostate Cancer by Antonarakis, Emmanuel S, Tagawa, Scott T, Galletti, Giuseppe, Worroll, Daniel, Ballman, Karla, Vanhuyse, Marie, Sonpavde, Guru, North, Scott, Albany, Costantine, Tsao, Che-Kai, Stewart, John, Zaher, Atef, Szatrowski, Ted, Zhou, Wei, Gjyrezi, Ada, Tasaki, Shinsuke, Portella, Luigi, Bai, Yang, Lannin, Timothy B, Suri, Shalu, Gruber, Conor N, Pratt, Erica D, Kirby, Brian J, Eisenberger, Mario A, Nanus, David M, Saad, Fred, Giannakakou, Paraskevi

“…Purpose The TAXYNERGY trial ( ClinicalTrials.gov identifier: NCT01718353) evaluated clinical benefit from early taxane switch and circulating tumor cell (CTC)…”
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anti-EGFR capture mitigates EMT- and chemoresistance-associated heterogeneity in a resistance-profiling CTC platform by Thege, Fredrik I., Gruber, Conor N., Cardle, Ian I., Cong, Sophie H., Lannin, Timothy B., Kirby, Brian J.

“…Capture and analysis of circulating tumor cells (CTCs) holds promise for diagnosing and guiding treatment of pancreatic cancer. To accurately monitor disease…”
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Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C) by Gruber, Conor N., Patel, Roosheel S., Trachtman, Rebecca, Lepow, Lauren, Amanat, Fatima, Krammer, Florian, Wilson, Karen M., Onel, Kenan, Geanon, Daniel, Tuballes, Kevin, Patel, Manishkumar, Mouskas, Konstantinos, O’Donnell, Timothy, Merritt, Elliot, Simons, Nicole W., Barcessat, Vanessa, Del Valle, Diane M., Udondem, Samantha, Kang, Gurpawan, Agashe, Charuta, Karekar, Neha, Grabowska, Joanna, Nie, Kai, Le Berichel, Jessica, Xie, Hui, Beckmann, Noam, Gangadharan, Sandeep, Ofori-Amanfo, George, Laserson, Uri, Rahman, Adeeb, Kim-Schulze, Seunghee, Charney, Alexander W., Gnjatic, Sacha, Gelb, Bruce D., Merad, Miriam, Bogunovic, Dusan

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