Search Results - "Grubbs, Gabrielle"

Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits by Ravichandran, Supriya, Coyle, Elizabeth M, Klenow, Laura, Tang, Juanjie, Grubbs, Gabrielle, Liu, Shufeng, Wang, Tony, Golding, Hana, Khurana, Surender

“…Multiple vaccine candidates against SARS-CoV-2 based on viral spike protein are under development. However, there is limited information on the quality of…”
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Antibody affinity and cross-variant neutralization of SARS-CoV-2 Omicron BA.1, BA.2 and BA.3 following third mRNA vaccination by Bellusci, Lorenza, Grubbs, Gabrielle, Zahra, Fatema Tuz, Forgacs, David, Golding, Hana, Ross, Ted M., Khurana, Surender

“…There is limited knowledge on durability of neutralization capacity and antibody affinity maturation generated following two versus three doses of SARS-CoV-2…”
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Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients by Tang, Juanjie, Ravichandran, Supriya, Lee, Youri, Grubbs, Gabrielle, Coyle, Elizabeth M., Klenow, Laura, Genser, Hollie, Golding, Hana, Khurana, Surender

“…Hospitalized COVID-19 patients often present with a large spectrum of clinical symptoms. There is a critical need to better understand the immune responses to…”
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Monoclonal antibodies targeting sites in respiratory syncytial virus attachment G protein provide protection against RSV-A and RSV-B in mice by Lee, Youri, Klenow, Laura, Coyle, Elizabeth M., Grubbs, Gabrielle, Golding, Hana, Khurana, Surender

“…Currently, only Palivizumab and Nirsevimab that target the respiratory syncytical virus (RSV) fusion protein are licensed for pre-treatment of infants…”
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Longitudinal proteome-wide antibody profiling in Marburg virus survivors identifies wing domain immunogen for vaccine design by Khurana, Surender, Grubbs, Gabrielle, Ravichandran, Supriya, Cluff, Emily, Kim, JungHyun, Kuehne, Ana I., Zak, Samantha, Dye, John M., Lutwama, Julius J., Herbert, Andrew S.

“…Limited knowledge exists on the quality of polyclonal antibody responses generated following Marburg virus (MARV) infection and its evolution in survivors. In…”
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Neutralization of SARS-CoV-2 Omicron BQ.1, BQ.1.1 and XBB.1 variants following SARS-CoV-2 infection or vaccination in children by Bellusci, Lorenza, Grubbs, Gabrielle, Sait, Shaimaa, Yonker, Lael M., Randolph, Adrienne G., Novak, Tanya, Kobayashi, Takuma, Khurana, Surender

“…Emergence of highly transmissible Omicron subvariants led to increased SARS-CoV-2 infection and disease in children. However, minimal knowledge exists…”
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Epitope diversity of SARS-CoV-2 hyperimmune intravenous human immunoglobulins and neutralization of variants of concern by Tang, Juanjie, Lee, Youri, Ravichandran, Supriya, Grubbs, Gabrielle, Huang, Chang, Stauft, Charles B., Wang, Tony, Golding, Basil, Golding, Hana, Khurana, Surender

“…Hyperimmune immunoglobulin (hCoV-2IG) generated from SARS-CoV-2 convalescent plasma (CP) are under evaluation in clinical trials. Here we explored the antibody…”
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Antibody affinity maturation and cross-variant activity following SARS-CoV-2 mRNA vaccination: Impact of prior exposure and sex by Tang, Juanjie, Grubbs, Gabrielle, Lee, Youri, Huang, Chang, Ravichandran, Supriya, Forgacs, David, Golding, Hana, Ross, Ted M, Khurana, Surender

“…Limited knowledge exists regarding antibody affinity maturation following mRNA vaccination in naïve vs. COVID-19 recovered individuals and potential sex…”
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Evolution of the Antigenic Landscape in Children and Young Adults with COVID-19 and MIS-C by Bellusci, Lorenza, Grubbs, Gabrielle, Sait, Shaimaa, Herbst, Katherine W, Salazar, Juan C, Khurana, Surender, The Connecticut Children's Covid Collaborative

“…There is minimal knowledge regarding the durability of neutralization capacity and level of binding antibody generated against the highly transmissible…”
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Glycosylation of H4 influenza strains with pandemic potential and susceptibilities to lung surfactant SP-D by Parsons, Lisa M, Zoueva, Olga, Grubbs, Gabrielle, Plant, Ewan, Jankowska, Ewa, Xie, Yijia, Song, Hao, Gao, George F, Ye, Zhiping, Khurana, Surender, Cipollo, John F

“…We recently reported that members of group 1 influenza A virus (IAV) containing H2, H5, H6, and H11 hemagglutinins (HAs) are resistant to lung surfactant…”
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SARS-CoV-2 mRNA vaccine induced higher antibody affinity and IgG titers against variants of concern in post-partum vs non-post-partum women by Lee, Youri, Grubbs, Gabrielle, Ramelli, Sabrina C., Levine, Andrea R., Bathula, Allison, Saharia, Kapil, Purcell, Madeleine, Singireddy, Shreya, Dugan, Colleen L., Kirchoff, Lindsey, Lankford, Allison, Cipriano, Sarah, Curto, Ryan A., Wu, Jocelyn, Raja, Katherine, Kelley, Emily, Herr, Daniel, Vannella, Kevin M., Ravichandran, Supriya, Tang, Juanjie, Harris, Anthony, Sajadi, Mohammad, Chertow, Daniel S., Grazioli, Alison, Khurana, Surender

“…Limited knowledge exists in post-partum women regarding durability of SARS-CoV-2 vaccine-induced antibody responses and their neutralising ability against…”
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Impact of Convalescent Plasma Therapy on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Profile in Coronavirus Disease 2019 (COVID-19) Patients by Tang, Juanjie, Grubbs, Gabrielle, Lee, Youri, Golding, Hana, Khurana, Surender

“…Abstract Convalescent plasma (CP) have been used for treatment of coronavirus disease 2019 (COVID-19), but their effectiveness varies significantly. Moreover,…”
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Neutralization of SARS-CoV-2 Omicron and other variants in serum from children with vaccination-induced myocarditis by Zahra, Fatema Tuz, Grubbs, Gabrielle, Dummer, Kirsten, Tremoulet, Adriana H., Shimizu, Chisato, Burns, Jane C., Khurana, Surender

“…Our study demonstrates that children who developed SARS-CoV-2 vaccination-induced myocarditis and may not receive another vaccination, could be susceptible to…”
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Neutralization of SARS-CoV-2 Omicron after vaccination of patients with myelodysplastic syndromes or acute myeloid leukemia by Bellusci, Lorenza, Grubbs, Gabrielle, Srivastava, Pragya, Nemeth, Michael J., Griffiths, Elizabeth A., Golding, Hana, Khurana, Surender

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SARS-CoV-2 immune repertoire in MIS-C and pediatric COVID-19 by Ravichandran, Supriya, Tang, Juanjie, Grubbs, Gabrielle, Lee, Youri, Pourhashemi, Sara, Hussaini, Laila, Lapp, Stacey A., Jerris, Robert C., Singh, Vidisha, Chahroudi, Ann, Anderson, Evan J., Rostad, Christina A., Khurana, Surender

“…There is limited understanding of the viral antibody fingerprint following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children…”
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Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron and Other Variants in Serum From Children With Vaccination-Induced Myocarditis by Zahra, Fatema Tuz, Grubbs, Gabrielle, Dummer, Kirsten, Tremoulet, Adriana H, Shimizu, Chisato, Burns, Jane C, Khurana, Surender

“…Our study demonstrates that children who developed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination-induced myocarditis and may not…”
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Influenza vaccination reveals sex dimorphic imprints of prior mild COVID-19 by Sparks, Rachel, Lau, William W., Liu, Can, Han, Kyu Lee, Vrindten, Kiera L., Sun, Guangping, Cox, Milann, Andrews, Sarah F., Bansal, Neha, Failla, Laura E., Manischewitz, Jody, Grubbs, Gabrielle, King, Lisa R., Koroleva, Galina, Leimenstoll, Stephanie, Snow, LaQuita, Chen, Jinguo, Tang, Juanjie, Mukherjee, Amrita, Sellers, Brian A., Apps, Richard, McDermott, Adrian B., Martins, Andrew J., Bloch, Evan M., Golding, Hana, Khurana, Surender, Tsang, John S.

“…Acute viral infections can have durable functional impacts on the immune system long after recovery, but how they affect homeostatic immune states and…”
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Increased Antibody Avidity and Cross-Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Variants by Hyperimmunized Transchromosomic Bovine–Derived Human Immunoglobulins for Treatment of Coronavirus Disease 2019 by Tang, Juanjie, Grubbs, Gabrielle, Lee, Youri, Wu, Hua, Luke, Thomas C, Egland, Kristi A, Bausch, Christoph L, Sullivan, Eddie J, Khurana, Surender

“…Abstract Passive antibody immunotherapeutics directed against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are promising countermeasures for…”
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mRNA vaccination induces persistent pharyngeal mucosal B cell responses to SARS-CoV-2 in children by Xu, Qin, Mudd, Pamela, Behzadpour, Hengameh, Newman, Daniel, Bellusci, Lorenza, Grubbs, Gabrielle, Tang, Juanjie, Liu, Can, Milanez-Almeida, Pedro, Martins, Andrew, Kardava, Lela, Moir, Susan, Khurana, Surender, Schwartzberg, Pamela, Manthiram, Kalpana

“…Abstract We recently reported that SARS-CoV-2 infection triggers robust, persistent adaptive immune responses in the tonsils and adenoids of children. However,…”
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Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children by Xu, Qin, Milanez-Almeida, Pedro, Martins, Andrew J., Radtke, Andrea J., Hoehn, Kenneth B., Oguz, Cihan, Chen, Jinguo, Liu, Can, Tang, Juanjie, Grubbs, Gabrielle, Stein, Sydney, Ramelli, Sabrina, Kabat, Juraj, Behzadpour, Hengameh, Karkanitsa, Maria, Spathies, Jacquelyn, Kalish, Heather, Kardava, Lela, Kirby, Martha, Cheung, Foo, Preite, Silvia, Duncker, Patrick C., Kitakule, Moses M., Romero, Nahir, Preciado, Diego, Gitman, Lyuba, Koroleva, Galina, Smith, Grace, Shaffer, Arthur, McBain, Ian T., McGuire, Peter J., Pittaluga, Stefania, Germain, Ronald N., Apps, Richard, Schwartz, Daniella M., Sadtler, Kaitlyn, Moir, Susan, Chertow, Daniel S., Kleinstein, Steven H., Khurana, Surender, Tsang, John S., Mudd, Pamela, Schwartzberg, Pamela L., Manthiram, Kalpana

“…Most studies of adaptive immunity to SARS-CoV-2 infection focus on peripheral blood, which may not fully reflect immune responses at the site of infection…”
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