Search Results - "Gruß, Hendrik"

Late‐Stage Diversification of Tryptophan‐Derived Biomolecules by Gruß, Hendrik, Sewald, Norbert

“…Pd‐mediated reactions have emerged as a powerful tool for the site‐selective and bioorthogonal late‐stage diversification of amino acids, peptides and related…”
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Fluorogenic Diversification of Unprotected Bromotryptophan by Aqueous Mizoroki–Heck Cross‐Coupling by Gruß, Hendrik, Belu, Clara, Bernhard, Laura M., Merschel, Arne, Sewald, Norbert

“…Fluorescent styryl‐tryptophans have been synthesized by a Mizoroki–Heck cross‐coupling from unprotected bromotryptophan in aqueous medium showing promising…”
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Suzuki–Miyaura Cross‐Coupling of Bromotryptophan Derivatives at Ambient Temperature by Dachwitz, Steffen, Duwe, Dario H., Wang, Yating Hong, Gruß, Hendrik, Hannappel, Yvonne, Hellweg, Thomas, Sewald, Norbert

“…Mild reaction conditions are highly desirable for bio‐orthogonal side chain derivatizations of amino acids, peptides or proteins due to the sensitivity of…”
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Iodine-Mediated Tryptathionine Formation Facilitates the Synthesis of Amanitins by Yao, Guiyang, Knittel, Caroline H, Kosol, Simone, Wenz, Marius T, Keller, Bettina G, Gruß, Hendrik, Braun, Alexandra C, Lutz, Christian, Hechler, Torsten, Pahl, Andreas, Süssmuth, Roderich D

“…Synthetic methods on the macrocyclization of peptides are of high interest since they facilitate the synthesis of various types of potentially bioactive…”
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One-step process for production of N-methylated amino acids from sugars and methylamine using recombinant Corynebacterium glutamicum as biocatalyst by Mindt, Melanie, Risse, Joe Max, Gruß, Hendrik, Sewald, Norbert, Eikmanns, Bernhard J., Wendisch, Volker F.

“…N -methylated amino acids are found in Nature in various biological compounds. N -methylation of amino acids has been shown to improve pharmacokinetic…”
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Guerbet Alcohols: From Processes under Harsh Conditions to Synthesis at Room Temperature under Ambient Pressure by Biermann, Marc, Gruß, Hendrik, Hummel, Werner, Gröger, Harald

“…A novel synthetic approach towards Guerbet alcohols, which are important intermediates in the production of plasticizers, lubricants, and surfactants, was…”
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Peptide stapling by late-stage Suzuki-Miyaura cross-coupling by Gruß, Hendrik, Feiner, Rebecca C, Mseya, Ridhiwan, Schröder, David C, Jewgiński, Michał, Müller, Kristian M, Latajka, Rafał, Marion, Antoine, Sewald, Norbert

“…The development of peptide stapling techniques to stabilise α-helical secondary structure motifs of peptides led to the design of modulators of protein-protein…”
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Corrigendum: Fluorogenic Diversification of Unprotected Bromotryptophan by Aqueous Mizoroki–Heck Cross‐Coupling by Gruß, Hendrik, Belu, Clara, Bernhard, Laura M., Merschel, Arne, Sewald, Norbert

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Abstract LB059: Multimeric linker-exatecan-based ADC targeting guanylyl cyclase C (GCC) as novel therapeutic modality for treatment of colorectal cancer by Neuberth, Sarah-Jane, Orlik, Christian, Palfi, Aniko, Mueller, Christoph, Gruss, Hendrik, Hechler, Torsten

“…Abstract Background: The approval of sacituzumabgovitecan (Trodelvy) and trastuzumab deruxtecan (Enhertu) demonstrated the potential of topoisomerase I…”
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