Search Results - "Groysman, Maya"
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Astrocytes contribute to remote memory formation by modulating hippocampal–cortical communication during learning
Published in Nature neuroscience (01-10-2020)“…Remote memories depend on coordinated activity in the hippocampus and frontal cortices, but the timeline of these interactions is debated. Astrocytes sense and…”
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Astrocytic Activation Generates De Novo Neuronal Potentiation and Memory Enhancement
Published in Cell (28-06-2018)“…Astrocytes respond to neuronal activity and were shown to be necessary for plasticity and memory. To test whether astrocytic activity is also sufficient to…”
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The Temporal Association Cortex Plays a Key Role in Auditory-Driven Maternal Plasticity
Published in Neuron (Cambridge, Mass.) (05-08-2020)“…Mother-infant bonding develops rapidly following parturition and is accompanied by changes in sensory perception and behavior. Here, we study how ultrasonic…”
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Mapping synaptic cortico‐claustral connectivity in the mouse
Published in Journal of comparative neurology (1911) (15-04-2017)“…The claustrum is an intriguing brain structure, featuring the highest connectivity per regional volume in the brain. It is a thin and elongated structure…”
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The Claustrum Supports Resilience to Distraction
Published in Current biology (10-09-2018)“…A barrage of information constantly assaults our senses, of which only a fraction is relevant at any given point in time. However, the neural circuitry…”
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Claustral Neurons Projecting to Frontal Cortex Mediate Contextual Association of Reward
Published in Current biology (21-09-2020)“…The claustrum is a small nucleus, exhibiting vast reciprocal connectivity with cortical, subcortical, and midbrain regions. Recent studies, including ours,…”
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Egr2 induction in spiny projection neurons of the ventrolateral striatum contributes to cocaine place preference in mice
Published in eLife (16-03-2021)“…Drug addiction develops due to brain-wide plasticity within neuronal ensembles, mediated by dynamic gene expression. Though the most common approach to…”
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Claustrum neurons projecting to the anterior cingulate restrict engagement during sleep and behavior
Published in Nature communications (26-06-2024)“…The claustrum has been linked to attention and sleep. We hypothesized that this reflects a shared function, determining responsiveness to stimuli, which spans…”
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A negative modulatory role for rho and rho-associated kinase signaling in delamination of neural crest cells
Published in Neural development (22-10-2008)“…Neural crest progenitors arise as epithelial cells and then undergo a process of epithelial to mesenchymal transition that precedes the generation of cellular…”
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Vav1 and Ly-GDI Two Regulators of Rho GTPases, Function Cooperatively as Signal Transducers in T Cell Antigen Receptor-induced Pathways
Published in The Journal of biological chemistry (20-12-2002)“…The Rho family GTPases are pivotal for T cell signaling; however, the regulation of these proteins is not fully known. One well studied regulator of Rho…”
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The haematopoietic specific signal transducer Vav1 is expressed in a subset of human neuroblastomas
Published in The Journal of pathology (01-04-2003)“…Vav1 is a signal transducer protein expressed exclusively in the haematopoietic system, where it plays a pivotal role in growth factor‐induced differentiation…”
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Engram stability and maturation during systems consolidation
Published in Current biology (25-09-2023)“…Remote memories play an important role in how we perceive the world, and they are rooted throughout the brain in “engrams”: ensembles of cells that are formed…”
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Astrocytes control recent and remote memory strength by affecting the recruitment of the CA1→ACC projection to engrams
Published in Cell reports (Cambridge) (26-03-2024)“…The maturation of engrams from recent to remote time points involves the recruitment of CA1 neurons projecting to the anterior cingulate cortex (CA1→ACC)…”
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Features of hippocampal astrocytic domains and their spatial relation to excitatory and inhibitory neurons
Published in Glia (01-10-2021)“…The mounting evidence for the involvement of astrocytes in neuronal circuits function and behavior stands in stark contrast to the lack of detailed anatomical…”
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Mutagenic analysis of Vav reveals that an intact SH3 domain is required for transformation
Published in Oncogene (24-09-1998)“…The vav proto-oncogene encodes a protein with multiple modulae domains that enable it to function as a mediator, linking tyrosine signaling to downstream…”
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Enhanced synaptic integration of adult-born neurons in the olfactory bulb of lactating mothers
Published in The Journal of neuroscience (30-05-2012)“…One of the most dramatic events during the life of adult mammals is the transition into motherhood. This transition is accompanied by specific maternal…”
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Functional transformations of odor inputs in the mouse olfactory bulb
Published in Frontiers in neural circuits (04-11-2014)“…Sensory inputs from the nasal epithelium to the olfactory bulb (OB) are organized as a discrete map in the glomerular layer (GL). This map is then modulated by…”
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Vav, a GDP/GTP nucleotide exchange factor, interacts with GDIs, proteins that inhibit GDP/GTP dissociation
Published in FEBS letters (04-02-2000)“…Vav functions as a specific GDP/GTP nucleotide exchange factor which is regulated by tyrosine phosphorylation in the hematopoietic system. Loss of the…”
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Signalling pathways induced by protease‐activated receptors and integrins in T cells
Published in Immunology (01-01-2002)“…Summary Recent characterization of the thrombin receptor indicates that it plays a role in T‐cell signalling pathways. However, little is known regarding the…”
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