Search Results - "Groyer, Ghislaine"

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders by Rupprecht, Rainer, Papadopoulos, Vassilios, Rammes, Gerhard, Baghai, Thomas C, Fan, Jinjiang, Akula, Nagaraju, Groyer, Ghislaine, Adams, David, Schumacher, Michael

“…Key Points The translocator protein (18 kDa) (TSPO) is a five transmembrane domain protein that is localized primarily in the outer mitochondrial membrane and…”
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Etifoxine improves peripheral nerve regeneration and functional recovery by Girard, Christelle, Liu, Song, Cadepond, Françoise, Adams, David, Lacroix, Catherine, Verleye, Marc, Gillardin, Jean-Marie, Baulieu, Etienne-Emile, Schumacher, Michael, Schweizer-Groyer, Ghislaine

“…Peripheral nerves show spontaneous regenerative responses, but recovery after injury or peripheral neuropathies (toxic, diabetic, or chronic inflammatory…”
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The cAMP-Responsive Unit of the Human Insulin-Like Growth Factor-Binding Protein-1 Coinstitutes a Functional Insulin-Response Element by SCHWEIZER-GROYER, GHISLAINE, FALLOT, GUILLAUME, CADEPOND, FRANÇOISE, GIRARD, CHRISTELLE, GROYER, ANDRÉ

“…:  Insulin‐like growth factor–binding protein‐1 (IGFBP‐1) is one of the genes involved in glucose homeostasis. In vivo, its level is increased by…”
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Mineralocorticoid and glucocorticoid receptors in sciatic nerve function and regeneration by Girard, Christelle, Eychenne, Bernard, Schweizer-Groyer, Ghislaine, Cadepond, Françoise

“…The contribution of the two corticosteroid (mineralocorticoid and glucocorticoid) receptor (MR and GR) pathways to the function and regeneration of the sciatic…”
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An evaluation of the role of insulin-like growth factors (IGF) and of type-I IGF receptor signalling in hepatocarcinogenesis and in the resistance of hepatocarcinoma cells against drug-induced apoptosis by Alexia, Catherine, Fallot, Guillaume, Lasfer, Malika, Schweizer-Groyer, Ghislaine, Groyer, André

“…Strong evidence emphasizes the role of the insulin-like growth factor (IGF) system and of type-I IGF receptor (IGF-IR) signalling in tumourigenesis. In this…”
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Glucocorticosteroid Receptor Dimerization Investigated by Analysis of Receptor Binding to Glucocorticosteroid Responsive Elements Using a Monomer−Dimer Equilibrium Model by Segard-Maurel, Ingrid, Rajkowski, Krzysztof, Jibard, Nicole, Schweizer-Groyer, Ghislaine, Baulieu, Etienne-Emile, Cadepond, Françoise

“…The aim of this study was to analyze the role of regions of the glucocorticosteroid receptor (GR) outside the DNA binding domain (DBD) in GR binding and…”
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Translocator protein (18 kDa) is involved in primitive erythropoiesis in zebrafish by Rampon, Christine, Bouzaffour, Mohamed, Ostuni, Mariano A, Dufourcq, Pascale, Girard, Christelle, Freyssinet, Jean Marie, Lacapere, Jean-Jacques, Schweizer-Groyer, Ghislaine, Vriz, Sophie

“…The translocator protein (18 kDa) (TSPO), also known as peripheral-type benzodiazepine receptor, is directly or indirectly associated with many biological…”
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Expression and Functional State of the Corticosteroid Receptors and 11β-Hydroxysteroid Dehydrogenase Type 2 in Schwann Cells by Groyer, Ghislaine, Eychenne, Bernard, Girard, Christelle, Rajkowski, Krzysztof, Schumacher, Michael, Cadepond, Françoise

“…To investigate the role of steroid receptors in mediating the reported effects of steroids on Schwann cell (SC) myelination and growth, we determined mRNA…”
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The Glucocorticoid Response Element II Is Functionally Homologous in Rat and Human Insulin-like Growth Factor-binding Protein-1 Promoters by Schweizer-Groyer, G, Jibard, N, Neau, E, Fortin, D, Cadepond, F, Baulieu, E E, Groyer, A

“…In vivo, insulin-like growth factor-binding protein-1 (IGFBP-1) modulates the IGFs’ bioavailability and may contribute to their delivery to peripheral…”
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Analgesic strategies aimed at stimulating the endogenous production of allopregnanolone by Poisbeau, Pierrick, Keller, Anne Florence, Aouad, Maya, Kamoun, Nisrine, Groyer, Ghislaine, Schumacher, Michael

“…A growing number of studies indicate that 3-alpha reduced neurosteroids are remarkable analgesics in various pain states. This is the case for allopregnanolone…”
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Inhibitory effect of insulin on cAMP response in hepatocytes: role of the phosphatidylinositol-3′kinase and of the transcription factor FKHR by Groyer, Ghislaine, Cadepond, Francoise, Groyer, Andre

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Downregulation of steroidogenic acute regulatory protein (StAR) gene expression by cyclic AMP in cultured Schwann cells by Benmessahel, Yasmina, Troadec, Jean-Denis, Cadepond, Françoise, Guennoun, Rachida, Hales, Dale Buchanan, Schumacher, Michael, Groyer, Ghislaine

“…Steroidogenic acute regulatory protein (StAR) plays a key role in the availability of cholesterol to the inner mitochondrial membrane, where the first step of…”
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Steroid Receptors in Various Glial Cell Lines Expression and Functional Studies by CADEPOND, FRANÇOISE, MASSAAD, CHARBEL, TROUSSON, AMALIA, GRENIER, JULIEN, GROYER, GHISLAINE, BAULIEU, ETIENNE, SCHUMACHER, MICHAEL

“…: In glial cell lines from the central (CG4, C6) and peripheral (MSC80, CR3a1, and CR1b4) nervous systems, glucocorticoid receptor (GR) messenger RNA was…”
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Heat shock protein 90 as a critical factor in maintaining glucocorticosteroid receptor in a nonfunctional state by Cadepond, F, Schweizer-Groyer, G, Segard-Maurel, I, Jibard, N, Hollenberg, S M, Giguère, V, Evans, R M, Baulieu, E E

“…Previous work demonstrated that the ligand binding domain (LBD) was required to determine the formation of the cytosolic, untransformed, inactive, 8 S,…”
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Delimitation of Two Regions in the 90-kDa Heat Shock Protein (Hsp90) Able to Interact with the Glucocorticosteroid Receptor (GR) by Jibard, Nicole, Meng, Xia, Leclerc, Philippe, Rajkowski, Krzysztof, Fortin, Dominique, Schweizer-Groyer, Ghislaine, Catelli, Maria-Grazia, Baulieu, Etienne-Emile, Cadepond, Françoise

“…The role of the 90-kDa heat shock protein (Hsp90) as a chaperone and its regulatory functions for cellular proteins such as the glucocorticosteroid receptor…”
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Hormonal regulation of the nuclear localization signals of the human glucocorticosteroid receptor by Cadepond, F, Gasc, J M, Delahaye, F, Jibard, N, Schweizer-Groyer, G, Segard-Maurel, I, Evans, R, Baulieu, E E

“…Nuclear localization of the rat glucocorticosteroid receptor (rGR) transiently expressed in COS-7 cells appears to be mediated by two nuclear localization…”
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Antiglucocorticosteroid effects suggest why steroid hormone is required for receptors to bind DNA in vivo but not in vitro by Groyer, André, Schweizer-Groyer, Ghislaine, Cadepond, Françoise, Mariller, Marcel, Baulieu, Etienne-Emile

“…Sequence-specific interaction between steroid hormone receptors (R) and DNA hormone-responsive elements (HRE) takes place in vitro irrespective of the presence…”
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Quantification of the Nucleocytoplasmic Distribution of Wild Type and Modified Proteins Using Confocal Microscopy: Interaction between 90-kDa Heat Shock Protein (Hsp90α) and Glucocorticosteroid Receptor (GR) by Leclerc, Philippe, Jibard, Nicole, Meng, Xia, Schweizer-Groyer, Ghislaine, Fortin, Dominique, Rajkowski, Krzysztof, Kang, Ki, Catelli, Maria-Grazia, Baulieu, Etienne-Emile, Cadepond, Françoise

“…The investigation of molecular interactions in whole cells by immunofluorescence was developed recently, based on the targeting of the protein partners to…”
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Stimulation of transcription in vitro from a liver-specific promoter by human glucocorticoid receptor (hGRalpha) by Schweizer-Groyer, G, Cadepond, F, Jibard, N, Neau, E, Segard-Maurel, I, Baulieu, E E, Groyer, A

“…The rat tyrosine aminotransferase (TAT) gene is a liver-specific and glucocorticoid-inducible gene. Previous studies have shown that the TAT promoter (TAT0.35;…”
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Expression from the tyrosine aminotransferase promoter (nt –350 to +1) is liver-specific and dependent on the binding of both liver-enriched and ubiquitous trans-acting factors by Schweizer-Groyer, Ghislaine, Groyer, André, Cadepond, Françoise, Grange, Thierry, Baulieu, Etienne-Emile, Pictet, Raymond

“…The rat tyrosine aminotransferase (TAT) gene promoter (nucleotides – 350 to +1; TAT0.35) was able to sustain liver-specific expression both ex vivo in…”
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