Search Results - "Grove, Melanie"

Polysialic Acid on Neuropilin-2 Is Exclusively Synthesized by the Polysialyltransferase ST8SiaIV and Attached to Mucin-type O-Glycans Located between the b2 and c Domain by Rollenhagen, Manuela, Buettner, Falk F.R., Reismann, Marc, Jirmo, Adan Chari, Grove, Melanie, Behrens, Georg M.N., Gerardy-Schahn, Rita, Hanisch, Franz-Georg, Mühlenhoff, Martina

“…Neuropilin-2 (NRP2) is well known as a co-receptor for class 3 semaphorins and vascular endothelial growth factors, involved in axon guidance and angiogenesis…”
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iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapy by Brücher, Dominik, Kirchhammer, Nicole, Smith, Sheena N., Schumacher, Jatina, Schumacher, Nina, Kolibius, Jonas, Freitag, Patrick C., Schmid, Markus, Weiss, Fabian, Keller, Corina, Grove, Melanie, Greber, Urs F., Zippelius, Alfred, Plückthun, Andreas

“…Adenovirus-mediated combination gene therapies have shown promising results in vaccination or treating malignant and genetic diseases. Nevertheless, an…”
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Proteolytic Release of the Intramolecular Chaperone Domain Confers Processivity to Endosialidase F by Schwarzer, David, Stummeyer, Katharina, Haselhorst, Thomas, Freiberger, Friedrich, Rode, Bastian, Grove, Melanie, Scheper, Thomas, von Itzstein, Mark, Mühlenhoff, Martina, Gerardy-Schahn, Rita

“…Endosialidases (endoNs), as identified so far, are tailspike proteins of bacteriophages that specifically bind and degrade the α2,8-linked polysialic acid…”
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Proteolytic Processing and Oligomerization of Bacteriophage-derived Endosialidases by Mühlenhoff, Martina, Stummeyer, Katharina, Grove, Melanie, Sauerborn, Markus, Gerardy-Schahn, Rita

“…Bacteriophages infecting the neuroinvasive pathogen Escherichia coli K1 require an endosialidase to penetrate the polysialic acid capsule of the host. Sequence…”
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Expression cloning of the human C3a anaphylatoxin receptor (C3aR) from differentiated U-937 cells by Crass, T, Raffetseder, U, Martin, U, Grove, M, Klos, A, Köhl, J, Bautsch, W

“…A cDNA clone encoding the human C3a anaphylatoxin receptor (C3aR) was isolated from a pcDNAI/Amp expression library prepared from U-937 cells which had been…”
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The FDA-Approved Drug Nelfinavir Inhibits Lytic Cell-Free but Not Cell-Associated Nonlytic Transmission of Human Adenovirus by Georgi, Fanny, Andriasyan, Vardan, Witte, Robert, Murer, Luca, Hemmi, Silvio, Yu, Lisa, Grove, Melanie, Meili, Nicole, Kuttler, Fabien, Yakimovich, Artur, Turcatti, Gerardo, Greber, Urs F

“…Adenoviruses (AdVs) are prevalent and give rise to chronic and recurrent disease. Human AdV (HAdV) species B and C, such as HAdV-C2, -C5, and -B14, cause…”
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The sialyl-O-acetylesterase NanS of Tannerella forsythia encompasses two catalytic modules with different regiospecificity for O7 and O9 of sialic acid by Albers, Malena, Schröter, Larissa, Belousov, Sergej, Hartmann, Maike, Grove, Melanie, Abeln, Markus, Mühlenhoff, Martina

“…Abstract The periodontal pathogen Tannerella forsythia utilizes host sialic acids as a nutrient source. To also make O-acetylated sialyl residues susceptible…”
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9-O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate by Baumann, Anna-Maria T., Bakkers, Mark J. G., Buettner, Falk F. R., Hartmann, Maike, Grove, Melanie, Langereis, Martijn A., de Groot, Raoul J., Mühlenhoff, Martina

“…Sialic acids, terminal sugars of glycoproteins and glycolipids, play important roles in development, cellular recognition processes and host–pathogen…”
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Proteolytic Release of the Intramolecular Chaperone Domain Confers Processivity to Endosialidase FS by Schwarzer, David, Stummeyer, Katharina, Haselhorst, Thomas, Freiberger, Friedrich, Rode, Bastian, Grove, Melanie, Scheper, Thomas, von Itzstein, Mark, Mühlenhoff, Martina, Gerardy-Schahn, Rita

“…Endosialidases (endoNs), as identified so far, are tailspike proteins of bacteriophages that specifically bind and degrade the α2,8-linked polysialic acid…”
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Cutting Edge: Guinea Pigs with a Natural C3a-Receptor Defect Exhibit Decreased Bronchoconstriction in Allergic Airway Disease: Evidence for an Involvement of the C3a Anaphylatoxin in the Pathogenesis of Asthma by Bautsch, Wilfried, Hoymann, Heinz-Gerd, Zhang, Qiuwang, Meier-Wiedenbach, Ivo, Raschke, Ursula, Ames, Robert S, Sohns, Bettina, Flemme, Nicole, Meyer zu Vilsendorf, Andreas, Grove, Melanie, Klos, Andreas, Kohl, Jorg

“…Asthma is a major cause of morbidity worldwide with prevalence and severity still increasing at an alarming pace. Hallmarks of this disease include early-phase…”
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Cutting Edge: Human Anaphylatoxin C4a Is a Potent Agonist of the Guinea Pig But Not the Human C3a Receptor by Lienenklaus, Stefan, Ames, Robert S, Tornetta, Mark A, Sarau, Henry M, Foley, James J, Crass, Torsten, Sohns, Bettina, Raffetseder, Ute, Grove, Melanie, Holzer, Anja, Klos, Andreas, Kohl, Jorg, Bautsch, Wilfried

“…Abstract The interaction of human anaphylatoxin C4a with the guinea pig (gp) and human (hu) C3a receptors (C3aR) was analyzed using human rC4a, which exhibited…”
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Genomic organization of the human C3a receptor by Paral, Daniela, Sohns, Bettina, Crass, Torsten, Grove, Melanie, Köhl, Jörg, Klos, Andreas, Bautsch, Wilfried

“…The human C3a receptor (C3aR) mediates the activation of cells by the potent proinflammatory chemoattractant C3a, an anaphylatoxin, generated in the early…”
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G α-16 complements the signal transduction cascade of chemotactic receptors for complement factor C5a (C5a-R) and N-formylated peptides (fMLF-R) in Xenopus laevis oocytes: G α-16 couples to chemotactic receptors in Xenopus oocytes by Burg, Michael, Raffetseder, Ute, Grove, Melanie, Klos, Andreas, Köhl, Jörg, Bautsch, Wilfried

“…The human leukocyte chemoattractant receptors for complement factor C5a (C5a-R) and N-formylated peptides (fMLF-R) are important members of the superfamily of…”
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