Search Results - "Groussard, Karine"

Cohort profile: COBLAnCE: a French prospective cohort to study prognostic and predictive factors in bladder cancer and to generate real-world data on treatment patterns, resource use and quality of life by Lebret, Thierry, Bonastre, Julia, Fraslin, Aldéric, Neuzillet, Yann, Droupy, Stéphane, Rebillard, Xavier, Vordos, Dimitri, Guy, Laurent, Villers, Arnauld, Schneider, Marc, Coloby, Patrick, Lacoste, Jean, Méjean, Arnaud, Lacoste, Jacques, Descotes, Jean-Luc, Eschwege, Pascal, Loison, Guillaume, Blanché, Hélène, Mariani, Odette, Ghaleh, Bijan, Mangin, Anthony, Sirab, Nanor, Groussard, Karine, Radvanyi, François, Allory, Yves, Benhamou, Simone

“…PurposeBladder cancer is a complex disease with a wide range of outcomes. Clinicopathological factors only partially explain the variability between patients…”
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The new orally active iron chelator ICL670A exhibits a higher antiproliferative effect in human hepatocyte cultures than O-trensox by Chantrel-Groussard, Karine, Gaboriau, François, Pasdeloup, Nicole, Havouis, René, Nick, Hanspeter, Pierre, Jean-Louis, Brissot, Pierre, Lescoat, Gérard

“…By comparing the antiproliferative effect of the iron chelators ICL670A and O-trensox in the human hepatoma cell line HUH7 and human hepatocyte cultures, we…”
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A prospective multicenter study on bladder cancer: the COBLAnCE cohort by Benhamou, Simone, Bonastre, Julia, Groussard, Karine, Radvanyi, François, Allory, Yves, Lebret, Thierry

“…Bladder cancer is a very heterogeneous disease as regards natural history. Environmental exposures, constitutional genetic and/or epigenetic background may…”
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A Case-Only Genome-Wide Interaction Study of Smoking and Bladder Cancer Risk: Results from the COBLAnCE Cohort by Karimi, Maryam, Mendez-Pineda, Sebastian, Blanché, Hélène, Boland, Anne, Besse, Céline, Deleuze, Jean-François, Meng, Xiang-Yu, Sirab, Nanor, Groussard, Karine, Lebret, Thierry, Bonastre, Julia, Allory, Yves, Radvanyi, François, Benhamou, Simone, Michiels, Stefan

“…Bladder cancer (BC) is the 6th most common cancer worldwide, with tobacco smoking considered as its main risk factor. Accumulating evidence has found…”
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Abstract 5224: Genome-wide interaction study of smoking and bladder cancer risk: results from the COBLAnCE cohort by Karimi, Maryam, Mendez-Pineda, Sebastian, Blanché, Hélène, Boland, Anne, Deleuze, Jean-François, Meng, Xiang-Yu, Groussard, Karine, Lebret, Thierry, Bonastre, Julia, Allory, Yves, Radvanyi, François, Benhamou, Simone, Michiels, Stefan

“…Introduction: Bladder Cancer (BC) is the 6th most common cancer and the 9th leading cause of cancer death among men worldwide. Tobacco smoking is the main risk…”
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Disabled early recruitment of antioxidant defenses in Friedreich's ataxia by CHANTREL-GROUSSARD, Karine, GEROMEL, Vanna, PUCCIO, Hélène, KOENIG, Michel, MUNNICH, Arnold, RÖTIG, Agnès, RUSTIN, Pierre

“…Friedreich's ataxia (FRDA) results from a generalized deficiency of mitochondrial iron-sulfur protein activity ascribed to mitochondrial iron overload…”
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Effect of idebenone on cardiomyopathy in Friedreich's ataxia: a preliminary study by Rustin, Pierre, von Kleist-Retzow, Jürgen-Christoph, Chantrel-Groussard, Karine, Sidi, Daniel, Munnich, Arnold, Rötig, Agnès

“…Friedreich's ataxia is caused by a deficiency of frataxin, a protein involved in regulation of mitochondrial iron content. We have reported a combined…”
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Comparative Effect of the Oral Iron Chelators ICL670A and CP20 on Cell Proliferation, Apoptosis and Polyamine Metabolism in Rat and Human Liver Cell Cultures by Gaboriau, François, Chantrel-Groussard, Karine, Pasdeloup, Nicole, Nick, Hans Peter, Brissot, Pierre, Lescoat, Gérard

“…Iron overload increases the mitotic index in rat hepatocyte cultures stimulated by EGF. Iron, implicated in tumoral cell proliferation, promotes the…”
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Measurement of ornithine decarboxylase activity in cell extracts using mass spectrometry detection of dansylated putrescine by Gaboriau, François, Havouis, René, Groussard, Karine, Moulinoux, Jacques-Philippe, Lescoat, Gérard

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Allelic losses in localized prostate cancer: association with prognostic factors by Fromont, Gaëlle, Joulin, Vincent, Chantrel-Groussard, Karine, Vallancien, Guy, Guillonneau, Bertrand, Validire, Pierre, Latil, Alain, Cussenot, Olivier

“…Loss of heterozygosity (LOH) is the most consistent genetic alteration in prostate cancer (CaP), frequently associated with advanced cancer and metastasis. We…”
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Iron mobilization, cytoprotection, and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20: a biological and physicochemical study by Gaboriau, François, Chantrel-Groussard, Karine, Rakba, Nafissa, Loyer, Pascal, Pasdeloup, Nicole, Hider, Robert C., Brissot, Pierre, Lescoat, Gérard

“…The present study analyzes the iron mobilization, the cytoprotective, and the antiproliferative effects of the lipophilic hydroxypyridinone CP411, in…”
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Cell complementation using Genebridge 4 human:rodent hybrids for physical mapping of novel mitochondrial respiratory chain deficiency genes by de Lonlay, Pascale, Mugnier, Claude, Sanlaville, Damien, Chantrel-Groussard, Karine, Bénit, Paule, Lebon, Sophie, Chrétien, Dominique, Kadhom, Noman, Saker, Safa, Gyapay, Gabor, Romana, Serge, Weissenbach, Jean, Munnich, Arnold, Rustin, Pierre, Rötig, Agnès

“…The mapping and identification of respiratory chain deficiency genes is particularly tedious owing to the large number of genes encoding catalytic subunits and…”
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Expression Study of Genes Involved in Iron Metabolism in Human Tissues by Rötig, Agnès, Chantrel-Groussard, Karine, Munnich, Arnold, Rustin, Pierre

“…Iron is required in all organisms for crucial functions, as a number of proteins need iron for activity. Mutations of the genes encoding proteins involved in…”
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High frequency of allelic losses in high-grade prostate cancer is associated with biochemical progression after radical prostatectomy by Valeri, Antoine, Fromont, Gaelle, Sakr, Wael, Azzouzi, Rahmène, Dey, Jyotirmoy, Chantrel-Groussard, Karine, Latil, Alain, Berthon, Philippe, Cussenot, Olivier, Pontes, J. Edson, Cher, Michael L.

“…Loss of heterozygosity (LOH) is the most consistent genetic change in prostate cancer (CaP). We aimed, to correlate specific LOH and the overall LOH frequency,…”
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Biochemical, genetic and immunoblot analyses of 17 patients with an isolated cytochrome c oxidase deficiency by von Kleist-Retzow, Jürgen-Christoph, Vial, Elodie, Chantrel-Groussard, Karine, Rötig, Agnès, Munnich, Arnold, Rustin, Pierre, Taanman, Jan-Willem

“…Mitochondrial respiratory chain defects involving cytochrome c oxidase (COX) are found in a clinically heterogeneous group of diseases, yet the molecular basis…”
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Ataxie de Friedreich : Une maladie mitochondriale due à une perturbation de l'homéostasie du fer dans les mitochondries by RUSTIN, P, VON KLEIST-RETZOW, J.-C, CHANTREL-GROUSSARD, K, SIDI, D, MUNNICH, A, RÖTIG, A

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Characterization of the murine gene for subunit VIIaL of cytochrome c oxidase by Chantrel-Groussard, K, Delpy, L, Ratinaud, M H, Cogné, M

“…Mammalian cytochrome c oxidase consists of thirteen subunits, ten encoded by the nuclear genome and three by the mitochondrial DNA. In several species, two…”
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