Search Results - "Grotzer, M"

Quassinoids: From traditional drugs to new cancer therapeutics by Fiaschetti, G, Grotzer, M A, Shalaby, T, Castelletti, D, Arcaro, A

“…Quassinoids are a group of compounds extracted from plants of the Simaroubaceae family, which have been used for many years in folk medicine. These molecules…”
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Correction: Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma by Fiaschetti, G., Castelletti, D., Zoller, S., Schramm, A., Schroeder, C., Nagaishi, M., Stearns, D., Mittelbronn, M., Eggert, A., Westermann, F., Ohgaki, H., Shalaby, T., Pruschy, M., Arcaro, A., Grotzer, M. A.

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Mobile Phone Use and Brain Tumors in Children and Adolescents: A Multicenter Case-Control Study by Aydin, Denis, Feychting, Maria, Schüz, Joachim, Tynes, Tore, Andersen, Tina Veje, Schmidt, Lisbeth Samsø, Poulsen, Aslak Harbo, Johansen, Christoffer, Prochazka, Michaela, Lannering, Birgitta, Klæboe, Lars, Eggen, Tone, Jenni, Daniela, Grotzer, Michael, Von der Weid, Nicolas, Kuehni, Claudia E., Röösli, Martin

“…Background It has been hypothesized that children and adolescents might be more vulnerable to possible health effects from mobile phone exposure than adults…”
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Epigenetic silencing of miRNA-9 is associated with HES1 oncogenic activity and poor prognosis of medulloblastoma by Fiaschetti, G, Abela, L, Nonoguchi, N, Dubuc, A M, Remke, M, Boro, A, Grunder, E, Siler, U, Ohgaki, H, Taylor, M D, Baumgartner, M, Shalaby, T, Grotzer, M A

“…Background: microRNA-9 is a key regulator of neuronal development aberrantly expressed in brain malignancies, including medulloblastoma. The mechanisms by…”
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Microbeam radiation therapy: Clinical perspectives by Grotzer, M.A, Schültke, E, Bräuer-Krisch, E, Laissue, J.A

“…Abstract Microbeam radiation therapy (MRT), a novel form of spatially fractionated radiotherapy (RT), uses arrays of synchrotron-generated X-ray microbeams…”
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Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas by Sutter, R, Shakhova, O, Bhagat, H, Behesti, H, Sutter, C, Penkar, S, Santuccione, A, Bernays, R, Heppner, F L, Schüller, U, Grotzer, M, Moch, H, Schraml, P, Marino, S

“…Cells with stem cell properties have been isolated from various areas of the postnatal mammalian brain, most recently from the postnatal mouse cerebellum. We…”
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Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours by von Bueren, A O, Bacolod, M D, Hagel, C, Heinimann, K, Fedier, A, Kordes, U, Pietsch, T, Koster, J, Grotzer, M A, Friedman, H S, Marra, G, Kool, M, Rutkowski, S

“…Background: Tumours are responsive to temozolomide (TMZ) if they are deficient in O 6 -methylguanine-DNA methyltransferase (MGMT), and mismatch repair (MMR)…”
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Hearing loss and quality of life in survivors of paediatric CNS tumours and other cancers by Weiss, Annette, Sommer, Grit, Schindera, Christina, Wengenroth, Laura, Karow, Axel, Diezi, Manuel, Michel, Gisela, Kuehni, Claudia E.

“…Purpose Hearing loss, a complication of cancer treatment, may reduce health-related quality of life (HRQoL), especially in childhood cancer survivors of…”
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Prospects for microbeam radiation therapy of brain tumours in children to reduce neurological sequelae by Laissue, JA, Blattmann, H, Wagner, H P, Grotzer, M A, Slatkin, D N

“…Microbeam radiation therapy (MRT), a form of experimental radiosurgery of tumours using multiple parallel, planar, micrometres‐wide, synchrotron‐generated…”
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Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells by Binz, N., Shalaby, T., Rivera, P., Shin-ya, K., Grotzer, M.A.

“…Neuroblastoma is a tumour derived from primitive cells of the sympathetic nervous system and is the most common extracranial solid tumour in childhood…”
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Outcome of medulloblastoma in children: long-term complications and quality of life by Ribi, K, Relly, C, Landolt, M A, Alber, F D, Boltshauser, E, Grotzer, M A

“…To study the outcomes in long-term survivors of paediatric medulloblastoma (MB), we followed 51 consecutive children who were treated between 1980 and 2000 in…”
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Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma by Fiaschetti, G, Castelletti, D, Zoller, S, Schramm, A, Schroeder, C, Nagaishi, M, Stearns, D, Mittelbronn, M, Eggert, A, Westermann, F, Ohgaki, H, Shalaby, T, Pruschy, M, Arcaro, A, Grotzer, M A

“…Medulloblastoma (MB) is the most common malignant brain tumor in children. It is known that overexpression and/or amplification of the MYC oncogene is…”
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Spatial clustering of childhood cancers in Switzerland: a nationwide study by Konstantinoudis, Garyfallos, Kreis, Christian, Ammann, Roland A., Niggli, Felix, Kuehni, Claudia E., Spycher, Ben D.

“…Purpose Childhood cancers are rare and little is known about their etiology. Potential risk factors include environmental exposures that might implicate…”
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Restricting growth and spreading of paediatric medulloblastoma by blocking kinase signalling-dependent brain infiltration by Tripolitsioti, D, Santhana Kumar, K, Neve, A, Pillong, M, Kunze, J, Schneider, G, Shalaby, T, Grotzer, M, Baumgartner, M

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Concentration, working speed and memory: Cognitive problems in young childhood cancer survivors and their siblings by Wengenroth, L., Rueegg, C. S., Michel, G., Gianinazzi, M. E., Essig, S., von der Weid, N. X., Grotzer, M., Kuehni, Claudia E.

“…Background Cognitive problems can have a negative effect on a person's education, but little is known about cognitive problems in young childhood cancer…”
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Synchrotron X-Ray Boost in the Microbeam Radiation Therapy Mode Improves Glioma Control After Conventional X-Ray Fractions by Bouchet, A, Potez, M.T, Flaender, M, Schaad, L, Rome, C, Farion, R, Laissue, J.A, Grotzer, M, Djonov, V, Elleaume, H, Brun, E, Serduc, R

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TrkC Expression Predicts Good Clinical Outcome in Primitive Neuroectodermal Brain Tumors by GROTZER, M. A, JANSS, A. J, TROJANOWSKI, J. Q, FUNG, K.-M, BIEGEL, J. A, SUTTON, L. N, RORKE, L. B, ZHAO, H, CNAAN, A, PHILLIPS, P. C, LEE, V. M.-Y

“…To identify biologic prognostic factors in childhood primitive neuroectodermal tumors (PNET), including medulloblastoma, that accurately define patient groups…”
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Antisense treatment of IGF-IR induces apoptosis and enhances chemosensitivity in central nervous system atypical teratoid/rhabdoid tumours cells by D’cunja, J, Shalaby, T, Rivera, P, von Büren, A, Patti, R, Heppner, F.L, Arcaro, A, Rorke-Adams, L.B, Phillips, P.C, Grotzer, M.A

“…Abstract Central nervous system (CNS) atypical teratoid/rhabdoid tumours (AT/RT) are among the paediatric malignant tumours with the worst prognosis and fatal…”
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Outcome in children with brain tumours diagnosed in the first year of life: long-term complications and quality of life by Gerber, N U, Zehnder, D, Zuzak, T J, Poretti, A, Boltshauser, E, Grotzer, M A

“…Objective:To study the outcome in children with brain tumours diagnosed in the first year of life, we followed up 27 consecutive children who were diagnosed…”
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Port-A-Cath infections in children with cancer by Hengartner, H., Berger, C., Nadal, D., Niggli, F.K., Grotzer, M.A.

“…Implanted subcutaneous (s.c.) central venous port accesses including Port-A-Cath (PAC) facilitate the administration of chemotherapy or blood products and are…”
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