Search Results - "Grotta, J C"

Safety of tPA in stroke mimics and neuroimaging-negative cerebral ischemia by CHERNYSHEV, O. Y, MARTIN-SCHILD, S, ALBRIGHT, K. C, BARRETO, A, MISRA, V, ACOSTA, I, GROTTA, J. C, SAVITZ, S. I

“…Patients with acute neurologic symptoms may have other causes simulating ischemic stroke, called stroke mimics (SM), but they may also have averted strokes…”
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Intraventricular hemorrhage : Anatomic relationships and clinical implications by HALLEVI, H, ALBRIGHT, K. C, ARONOWSKI, J, BARRETO, A. D, MARTIN-SCHILD, S, KHAJA, A. M, GONZALES, N. R, ILLOH, K, NOSER, E. A, GROTTA, J. C

“…Spontaneous intracerebral hemorrhage (ICH) is frequently associated with intraventricular hemorrhage (IVH), which is an independent predictor of poor outcome…”
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Early stroke treatment associated with better outcome : The NINDS rt-PA Stroke Study by MARLER, J. R, TILLEY, B. C, HALEY, E. C, LEWANDOWSKI, C. A, KWIATKOWSKI, T. P, LU, M, BROTT, T. G, LYDEN, P. C, GROTTA, J. C, BRODERICK, J. P, LEVINE, S. R, FRANKEL, M. P, HOROWITZ, S. H

“…The National Institute of Neurological Disorders and Stroke (NINDS) rt-PA Stroke Study showed a similar percentage of intracranial hemorrhage and good outcome…”
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Pulse pressure variability is associated with unfavorable outcomes in acute ischaemic stroke patients treated with intravenous thrombolysis by Katsanos, A. H., Alexandrov, A. V., Mandava, P., Köhrmann, M., Soinne, L., Barreto, A. D., Sharma, V. K., Mikulik, R., Muir, K. W., Rothlisberger, T., Grotta, J. C., Levi, C. R., Molina, C. A., Saqqur, M., Palaiodimou, L., Psaltopoulou, T., Vosko, M. R., Moreira, T., Fiebach, J. B., Rubiera, M., Sandset, E. C., Havenon, A., Kent, T. A., Alexandrov, A. W., Schellinger, P. D., Tsivgoulis, G.

“…Background and purpose Blood pressure (BP) variability has been associated with worse neurological outcomes in acute ischaemic stroke (AIS) patients receiving…”
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Rebleeding leads to poor outcome in ultra-early craniotomy for intracerebral hemorrhage by MORGENSTERN, L. B, DEMCHUK, A. M, KIM, D. H, FRANKOWSKI, R. F, GROTTA, J. C

“…A modest benefit was previously demonstrated for hematoma evacuation within 12 hours of intracerebral hemorrhage onset. Perhaps surgery within 4 hours would…”
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Surgical treatment for intracerebral hemorrhage (STICH) : A single-center, randomized clinical trial by MORGENSTERN, L. B, FRANKOWSKI, R. F, SHEDDEN, P, PASTEUR, W, GROTTA, J. C

“…To perform a single-center pilot investigation of early hematoma removal in patients with intracerebral hemorrhage (ICH). Considerable debate remains regarding…”
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Patient Refusal of Thrombolytic Therapy for Suspected Acute Ischemic Stroke by Vahidy, F. S., Rahbar, M. H., Lal, A. P., Grotta, J. C., Savitz, S. I.

“…Objective To determine factors associated with patients refusing IV t-PA for suspected acute ischemic stroke (AIS), and to compare the outcomes of patients who…”
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Reperfusion injury: demonstration of brain damage produced by reperfusion after transient focal ischemia in rats by Aronowski, J, Strong, R, Grotta, J C

“…During reperfusion after ischemia, deleterious biochemical processes can be triggered that may antagonize the beneficial effects of reperfusion. Research into…”
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Intravenous tissue plasminogen activator for acute ischemic Stroke : Feasibility, safety, and efficacy in the first year of clinical practice by CHIU, D, KRIEGER, D, VILLAR-CORDOVA, C, KASNER, S. E, MORGENSTERN, L. B, BRATINA, P. L, YATSU, F. M, GROTTA, J. C

“…The feasibility, safety, and efficacy of intravenous tissue plasminogen activator (t-PA) for patients with acute ischemic stroke in clinical practice need to…”
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High rate of complete recanalization and dramatic clinical recovery during tPA infusion when continuously monitored with 2-MHz transcranial Doppler monitoring by ALEXANDROV, A. V, DEMCHUK, A. M, FELBERG, R. A, CHRISTOU, I, BARBER, P. A, BURGIN, W. S, MALKOFF, M, WOJNER, A. W, GROTTA, J. C

“…Clot dissolution with tissue plasminogen activator (tPA) can lead to early clinical recovery after stroke. Transcranial Doppler (TCD) with low MHz frequency…”
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Clinical features of Moyamoya disease in the United States by CHIU, D, SHEDDEN, P, BRATINA, P, GROTTA, J. C

“…We report the clinical features and longitudinal outcome of the largest cohort of patients with moyamoya disease described from a single institution in the…”
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The Effect of Transcatheter Injections on Cell Viability and Cytokine Release of Mononuclear Cells by EL KHOURY, R, MISRA, V, SHARMA, S, COX, C. S, WALKER, P, GROTTA, J. C, GEE, A, SUZUKI, S, SAVITZ, S. I

“…Several studies suggest that various types of cellular therapies enhance recovery after stroke in animal models. IA-based delivery of cells to the brain is…”
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Safety of High Doses of Urokinase and Reteplase for Acute Ischemic Stroke by MISRA, V, EL KHOURY, R, ARORA, R, CHEN, P. R, SUZUKI, S, HARUN, N, GONZALES, N. R, BARRETO, A. D, GROTTA, J. C, SAVITZ, S. I

“…ET is considered in selected patients with AIS with persistent arterial occlusion after receiving IVT. Limited data exist on the safety of IA high doses of UK…”
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Myocardial injury in patients with intracerebral hemorrhage treated with recombinant factor VIIa by SUGG, R. M, GONZALES, N. R, MATHERNE, D. E, RIBO, M, SHALTONI, H. M, BARANIUK, S, NOSER, E. A, GROTTA, J. C

“…We report myocardial injury in 20 recombinant factor VIIa (rFVIIa) treated and 110 nontreated patients with intracerebral hemorrhage. Patients were treated or…”
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Timing of recanalization after tissue plasminogen activator therapy determined by transcranial Doppler correlates with clinical recovery from ischemic stroke by CHRISTOU, I, ALEXANDROV, A. V, BURGIN, W. S, WOJNER, A. W, FELBERG, R. A, MALKOFF, M, GROTTA, J. C

“…The duration of cerebral blood flow impairment correlates with irreversibility of brain damage in animal models of cerebral ischemia. Our aim was to correlate…”
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Worst headache and subarachnoid hemorrhage : Prospective, Modern computed tomography and spinal fluid analysis by MORGENSTERN, L. B, LUNA-GONZALES, H, HUBER, J. C, WONG, S. S, UTHMAN, M. O, GURIAN, J. H, CASTILLO, P. R, SHAW, S. G, FRANKOWSKI, R. F, GROTTA, J. C

“…This study investigated the hypothesis that modern computed tomographic (CT) imaging is sufficient to exclude subarachnoid hemorrhage (SAH) in patients with…”
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Intra-Arterial Reteplase Compared to Urokinase for Thrombolytic Recanalization in Acute Ischemic Stroke by Sugg, R.M, Noser, E.A, Shaltoni, H.M, Gonzales, N.R, Campbell, M.S, Weir, R, Cacayorin, E.D, Grotta, J.C

“…Reteplase (RP) and urokinase (UK) are being used "off-label" to treat acute ischemic stroke. The safety and efficacy of intra-arterial RP or UK in the…”
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Transcranial Doppler ultrasound criteria for recanalization after thrombolysis for middle cerebral artery stroke by BURGIN, W. S, MALKOFF, M, FELBERG, R. A, DEMCHUK, A. M, CHRISTOU, I, GROTTA, J. C, ALEXANDROV, A. V

“…Transcranial Doppler (TCD) can demonstrate arterial occlusion and subsequent recanalization in acute ischemic stroke patients treated with intravenous tissue…”
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Serum glucose level and diabetes predict tissue plasminogen activator-related intracerebral hemorrhage in acute ischemic Stroke by DEMCHUK, A. M, MORGENSTERN, L. B, KRIEGER, D. W, CHI, T. L, HU, W, WEIN, T. H, HARDY, R. J, GROTTA, J. C, BUCHAN, A. M

“…Five pretreatment variables (P<0.1 univariate analysis), including serum glucose (>300 mg/dL), predicted symptomatic intracerebral hemorrhage (ICH) in the…”
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Clinical deterioration following improvement in the NINDS rt-PA Stroke Trial by GROTTA, James C, WELCH, K. M. A, FAGAN, Susan C, MEI LU, FRANKEL, Michael R, BROTT, Thomas, LEVINE, Steven R, LYDEN, Patrick D

“…Little is known in regard to cerebral arterial reocclusion after successful thrombolysis. In the absence of arteriographic information, the National Institute…”
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