Search Results - "Grote, Isabel"

Concordance in detection of microsatellite instability by PCR and NGS in routinely processed tumor specimens of several cancer types by Bartels, Stephan, Grote, Isabel, Wagner, Madeleine, Boog, Jannik, Schipper, Elisa, Reineke‐Plaass, Tanja, Kreipe, Hans, Lehmann, Ulrich

“…Background Microsatellite instability (MSI) occurs in several cancer types and is commonly used for prognosis and as a predictive biomarker for immune…”
Get full text

TP53 mutations are associated with primary endocrine resistance in luminal early breast cancer by Grote, Isabel, Bartels, Stephan, Kandt, Leonie, Bollmann, Laura, Christgen, Henriette, Gronewold, Malte, Raap, Mieke, Lehmann, Ulrich, Gluz, Oleg, Nitz, Ulrike, Kuemmel, Sherko, Eulenburg, Christine, Braun, Michael, Aktas, Bahriye, Grischke, Eva‐Maria, Schumacher, Claudia, Luedtke‐Heckenkamp, Kerstin, Kates, Ronald, Wuerstlein, Rachel, Graeser, Monika, Harbeck, Nadia, Christgen, Matthias, Kreipe, Hans

“…Background Whereas the genomic landscape of endocrine‐resistant breast cancer has been intensely characterized in previously treated cases with local or…”
Get full text

Microenvironment‐induced restoration of cohesive growth associated with focal activation of P‐cadherin expression in lobular breast carcinoma metastatic to the colon by Gronewold, Malte, Grote, Isabel, Bartels, Stephan, Christgen, Henriette, Kandt, Leonie D, Brito, Maria Jose, Cserni, Gàbor, Daemmrich, Maximilian E, Fogt, Franz, Helmke, Burkhard M, Hoeve, Natalie, Lang‐Schwarz, Corinna, Vieth, Michael, Wellmann, Axel, Kuehnle, Elna, Kulik, Ulf, Riedel, Gesa, Reineke‐Plaass, Tanja, Lehmann, Ulrich, Koorman, Thijs, Derksen, Patrick WB, Kreipe, Hans, Christgen, Matthias

“…Invasive lobular carcinoma (ILC) is a special breast cancer type characterized by noncohesive growth and E‐cadherin loss. Focal activation of P‐cadherin…”
Get full text

Chromosome 2q gain and epigenetic silencing of GATA3 in microglandular adenosis of the breast by Radner, Martin, Luttikhuizen, Jana Lisa, Bartels, Stephan, Bublitz, Janin, Grote, Isabel, Rieger, Luisa, Christgen, Henriette, Stark, Helge, Werlein, Christopher, Lafos, Marcel, Steinemann, Doris, Lehmann, Ulrich, Christgen, Matthias, Kreipe, Hans

“…Microglandular adenosis (MGA) represents a rare neoplasm of the mammary gland, which in a subset of cases may be associated with triple‐negative breast cancer…”
Get full text

Frequency of genetic alterations differs in advanced breast cancer between metastatic sites by Grote, Isabel, Poppe, Alexandra, Lehmann, Ulrich, Christgen, Matthias, Kreipe, Hans, Bartels, Stephan

“…About 20%–30% of breast cancer (BC) patients will develop distant metastases, preferentially in bones, liver, lung, and brain. BCs with different intrinsic…”
Get full text

p53 Expression in Luminal Breast Cancer Correlates With TP53 Mutation and Primary Endocrine Resistance by Mueller, Sophie, Grote, Isabel, Bartels, Stephan, Kandt, Leonie, Christgen, Henriette, Lehmann, Ulrich, Gluz, Oleg, Graeser, Monika, Kates, Ron, Harbeck, Nadia, Kreipe, Hans, Christgen, Matthias

“…TP53 mutation is associated with primary endocrine resistance in luminal breast cancer (BC). Nuclear accumulation of p53, as determined by immunohistochemistry…”
Get full text

Evaluation of the routine use of E‐cadherin immunohistochemistry in the typing of breast carcinomas: results of a randomized diagnostic study by Cserni, Gábor, Kálmán, Endre, Udvarhelyi, Nóra, Papp, Eszter, Grote, Isabel, Bartels, Stephan, Christgen, Matthias, Kreipe, Hans, Kulka, Janina

“…Aims Invasive lobular carcinoma (ILC) has distinct morphology and association with loss of E‐cadherin function. It has special clinical and imaging features,…”
Get full text

ERBB2 mutation is associated with sustained tumor cell proliferation after short-term preoperative endocrine therapy in early lobular breast cancer by Grote, Isabel, Bartels, Stephan, Christgen, Henriette, Radner, Martin, Gronewold, Malte, Kandt, Leonie, Raap, Mieke, Lehmann, Ulrich, Gluz, Oleg, Graeser, Monika, Kuemmel, Sherko, Nitz, Ulrike, Harbeck, Nadia, Kreipe, Hans, Christgen, Matthias

“…Invasive lobular breast cancer (ILC) is a special breast cancer (BC) subtype and is mostly hormone receptor (HR)-positive and ERBB2 non-amplified. Endocrine…”
Get full text