Search Results - "Groszmann, Roberto"

Evolution in the understanding of the pathophysiological basis of portal hypertension: How changes in paradigm are leading to successful new treatments by Bosch, Jaume, Groszmann, Roberto J, Shah, Vijay H

“…Summary Among the common complication of cirrhosis portal hypertension witnessed a major improvement of prognosis during the past decades. Principally due to…”
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Vascular endothelial dysfunction in cirrhosis by Iwakiri, Yasuko, Groszmann, Roberto J

“…Endothelial dysfunction is regarded as an early key event in multiple diseases. The assessment of vascular nitric oxide (NO) level is an indicative of…”
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The hyperdynamic circulation of chronic liver diseases: From the patient to the molecule by Iwakiri, Yasuko, Groszmann, Roberto J.

“…The hyperdynamic circulatory syndrome observed in chronic liver diseases is a great example of research that originated from clinical observations and…”
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Lowering Portal Pressure Improves Outcomes of Patients With Cirrhosis, With or Without Ascites: A Meta-Analysis by Turco, Laura, Villanueva, Candid, La Mura, Vincenzo, García-Pagán, Juan Carlos, Reiberger, Thomas, Genescà, Joan, Groszmann, Roberto J., Sharma, Barjesh C., Merkel, Carlo, Bureau, Christophe, Alvarado, Edilmar, Abraldes, Juan Gonzalez, Albillos, Agustin, Bañares, Rafael, Peck-Radosavljevic, Markus, Augustin, Salvador, Sarin, Shiv K., Bosch, Jaime, García-Tsao, Guadalupe

“…In unselected patients with cirrhosis, those with reductions in hepatic venous pressure gradient (HVPG) to below a defined threshold (responders) have a…”
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Quantitative histological-hemodynamic correlations in cirrhosis by Sethasine, Supatsri, Jain, Dhanpat, Groszmann, Roberto J., Garcia-Tsao, Guadalupe

“…We have previously shown, in a semiquantitative analysis of liver biopsies showing cirrhosis, that thickness of fibrous septa separating cirrhotic nodules and…”
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Portal hypertension and variceal bleeding—Unresolved issues. Summary of an American Association for the study of liver diseases and European Association for the study of the liver single‐topic conference by Garcia‐Tsao, Guadalupe, Bosch, Jaime, Groszmann, Roberto J.

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The hepatic venous pressure gradient: Anything worth doing should be done right by Groszmann, Roberto J., Wongcharatrawee, Suchat

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Hepatic venous pressure gradient predicts development of hepatocellular carcinoma independently of severity of cirrhosis by Ripoll, Cristina, Groszmann, Roberto J, Garcia-Tsao, Guadalupe, Bosch, Jaime, Grace, Norman, Burroughs, Andrew, Planas, Ramon, Escorsell, Angels, Garcia-Pagan, Juan Carlos, Makuch, Robert, Patch, David, Matloff, Daniel S

“…Background/Aims A total of 213 patients with compensated cirrhosis, portal hypertension and no varices were included in a trial evaluating beta-blockers in…”
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Primary prophylaxis of variceal bleeding in children and the role of MesoRex Bypass: Summary of the Baveno VI Pediatric Satellite Symposium by Shneider, Benjamin L., de Ville de Goyet, Jean, Leung, Daniel H., Srivastava, Anshu, Ling, Simon C., Duché, Mathieu, McKiernan, Patrick, Superina, Riccardo, Squires, Robert H., Bosch, Jaime, Groszmann, Roberto, Sarin, Shiv K., de Franchis, Roberto, Mazariegos, George V.

“…Approaches to the management of portal hypertension and variceal hemorrhage in pediatrics remain controversial, in large part because they are not well…”
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Obesity is an independent risk factor for clinical decompensation in patients with cirrhosis by Berzigotti, Annalisa, Garcia‐Tsao, Guadalupe, Bosch, Jaime, Grace, Norman D., Burroughs, Andrew K., Morillas, Rosa, Escorsell, Angels, Garcia‐Pagan, Juan Carlos, Patch, David, Matloff, Daniel S., Groszmann, Roberto J.

“…Obesity is associated with an aggressive course in chronic viral hepatitis; however, its impact in the development of clinical decompensation (CD) in patients…”
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Prevention of portal hypertension: From variceal development to clinical decompensation by Vorobioff, Julio D., Groszmann, Roberto J.

“…Pharmacological treatment of portal hypertension (PH) has been exclusively devoted to gastroesophageal varices–related events at different frameworks,…”
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Novel inflammatory biomarkers of portal pressure in compensated cirrhosis patients by Buck, Martina, Garcia‐Tsao, Guadalupe, Groszmann, Roberto J., Stalling, Caitlin, Grace, Norman D., Burroughs, Andrew K., Patch, David, Matloff, Daniel S., Clopton, Paul, Chojkier, Mario

“…The rationale for screening inflammatory serum biomarkers of the hepatic vein pressure gradient (HVPG) is based on the fact that portal hypertension is…”
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The paradox of nitric oxide in cirrhosis and portal hypertension: Too much, not enough by Wiest, Reiner, Groszmann, Roberto J.

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Histological-hemodynamic correlation in cirrhosis—a histological classification of the severity of cirrhosis by Nagula, Satish, Jain, Dhanpat, Groszmann, Roberto J., Garcia-Tsao, Guadalupe

“…While the definitive diagnosis of cirrhosis is histological, it is the degree of portal hypertension, as determined by the hepatic venous pressure gradient…”
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Nitric Oxide Synthase Generates Nitric Oxide Locally to Regulate Compartmentalized Protein S-Nitrosylation and Protein Trafficking by Iwakiri, Yasuko, Satoh, Ayano, Chatterjee, Suvro, Toomre, Derek K., Chalouni, Cecile M., Fulton, David, Groszmann, Roberto J., Shah, Vijay H., Sessa, William C.

“…Nitric oxide (NO) is a highly diffusible and short-lived physiological messenger. Despite its diffusible nature, NO modifies thiol groups of specific cysteine…”
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Child-Turcotte-Pugh Class is Best at Stratifying Risk in Variceal Hemorrhage: Analysis of a US Multicenter Prospective Study by Fortune, Brett E, Garcia-Tsao, Guadalupe, Ciarleglio, Maria, Deng, Yanhong, Fallon, Michael B, Sigal, Samuel, Chalasani, Naga P, Lim, Joseph K, Reuben, Adrian, Vargas, Hugo E, Abrams, Gary, Lewis, Michele D, Hassanein, Tarek, Trotter, James F, Sanyal, Arun J, Beavers, Kimberly L, Ganger, Daniel, Thuluvath, Paul J, Grace, Norman D, Groszmann, Roberto J

“…GOALS/BACKGROUND:Data on acute variceal hemorrhage (AVH) in the United States is limited and the best method to stratify risk is not clear. Taking advantage of…”
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Portal Hypertension in Children: Expert Pediatric Opinion on the Report of the Baveno V Consensus Workshop on Methodology of Diagnosis and Therapy in Portal Hypertension by Shneider, Benjamin L., Bosch, Jaime, de Franchis, Roberto, Emre, Sukru H., Groszmann, Roberto J., Ling, Simon C., Lorenz, Jonathan M., Squires, Robert H., Superina, Riccardo A., Thompson, Ann E., Mazariegos, George V.

“…Shneider BL, Bosch J, de Franchis R, Emre SH, Groszmann RJ, Ling SC, Lorenz JM, Squires RH, Superina RA, Thompson AE, Mazariegos GV. Portal Hypertension in…”
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Incidence, Prevalence, and Clinical Significance of Abnormal Hematologic Indices in Compensated Cirrhosis by Qamar, Amir A, Grace, Norman D, Groszmann, Roberto J, Garcia–Tsao, Guadalupe, Bosch, Jaime, Burroughs, Andrew K, Ripoll, Cristina, Maurer, Rie, Planas, Ramon, Escorsell, Angels, Garcia–Pagan, Juan Carlos, Patch, David, Matloff, Daniel S, Makuch, Robert, Rendon, Gabriel

“…Background & Aims Patients with cirrhosis develop abnormal hematologic indices (HI) from multiple factors, including hypersplenism. We aimed to analyze the…”
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Beta-Blockers to Prevent Gastroesophageal Varices in Patients with Cirrhosis by Groszmann, Roberto J, Garcia-Tsao, Guadalupe, Bosch, Jaime, Grace, Norman D, Burroughs, Andrew K, Planas, Ramon, Escorsell, Angels, Garcia-Pagan, Juan Carlos, Patch, David, Matloff, Daniel S, Gao, Hong, Makuch, Robert

“…Beta-blockers prevent variceal bleeding in patients with cirrhosis who already have esophageal varices. In this randomized, placebo-controlled trial, timolol…”
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Introducing the AASLD president: Guadalupe Garcia-Tsao by Groszmann, Roberto J.

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