Search Results - "Grossniklaus, Hans"

Understanding Uveal Melanoma Metastasis to the Liver: The Zimmerman Effect and the Zimmerman Hypothesis by Grossniklaus, Hans E.

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Retinoblastoma. Fifty Years of Progress. The LXXI Edward Jackson Memorial Lecture by Grossniklaus, Hans E

“…Purpose To review the progress made in understanding the genetic basis, molecular pathology, and treatment of retinoblastoma since the previous Jackson lecture…”
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Ocular drug delivery targeted by iontophoresis in the suprachoroidal space using a microneedle by Jung, Jae Hwan, Chiang, Bryce, Grossniklaus, Hans E., Prausnitz, Mark R.

“…Treatment of many posterior-segment ocular indications would benefit from improved targeting of drug delivery to the back of the eye. Here, we propose the use…”
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Progression of ocular melanoma metastasis to the liver: the 2012 Zimmerman lecture by Grossniklaus, Hans E

“…To the best of my knowledge, this study demonstrates for the first time small, apparently dormant micrometastasis in the liver of patients with uveal melanoma…”
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Age-related retinopathy in NRF2-deficient mice by Zhao, Zhenyang, Chen, Yan, Wang, Jian, Sternberg, Paul, Freeman, Michael L, Grossniklaus, Hans E, Cai, Jiyang

“…Cumulative oxidative damage is implicated in the pathogenesis of age-related macular degeneration (AMD). Nuclear factor erythroid 2-related factor 2 (NRF2) is…”
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Uveal Melanoma Nuclear BRCA1-Associated Protein-1 Immunoreactivity Is an Indicator of Metastasis by Szalai, Eszter, Wells, Jill R., Ward, Laura, Grossniklaus, Hans E.

“…To examine the BRCA1-associated protein-1 (BAP1) expression of primary uveal melanomas without and with metastasis, and to analyze the correlation between the…”
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Vimentin Is Required for Lung Adenocarcinoma Metastasis via Heterotypic Tumor Cell-Cancer-Associated Fibroblast Interactions during Collective Invasion by Richardson, Alessandra M, Havel, Lauren S, Koyen, Allyson E, Konen, Jessica M, Shupe, John, Wiles, 4th, W G, Martin, W David, Grossniklaus, Hans E, Sica, Gabriel, Gilbert-Ross, Melissa, Marcus, Adam I

“…Vimentin is an epithelial-to-mesenchymal transition (EMT) biomarker and intermediate filament protein that functions during cell migration to maintain…”
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Metastatic uveal melanoma: The final frontier by Rantala, Elina S., Hernberg, Micaela M., Piperno-Neumann, Sophie, Grossniklaus, Hans E., Kivelä, Tero T.

“…Treatment of primary intraocular uveal melanoma has developed considerably, its driver genes are largely unraveled, and the ways to assess its risk for…”
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Consensus Nomenclature for Reporting Neovascular Age-Related Macular Degeneration Data: Consensus on Neovascular Age-Related Macular Degeneration Nomenclature Study Group by Spaide, Richard F, Jaffe, Glenn J, Sarraf, David, Freund, K Bailey, Sadda, Srinivas R, Staurenghi, Giovanni, Waheed, Nadia K, Chakravarthy, Usha, Rosenfeld, Philip J, Holz, Frank G, Souied, Eric H, Cohen, Salomon Y, Querques, Giuseppe, Ohno-Matsui, Kyoko, Boyer, David, Gaudric, Alain, Blodi, Barbara, Baumal, Caroline R, Li, Xiaoxin, Coscas, Gabriel J, Brucker, Alexander, Singerman, Lawrence, Luthert, Phil, Schmitz-Valckenberg, Steffen, Schmidt-Erfurth, Ursula, Grossniklaus, Hans E, Wilson, David J, Guymer, Robyn, Yannuzzi, Lawrence A, Chew, Emily Y, Csaky, Karl, Monés, Jordi M, Pauleikhoff, Daniel, Tadayoni, Ramin, Fujimoto, James

“…To establish a process to evaluate and standardize a state-of-the-art nomenclature for reporting neovascular age-related macular degeneration (AMD) data…”
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Animal models of choroidal and retinal neovascularization by Grossniklaus, Hans E., Kang, Shin J., Berglin, Lennart

“…There have been numerous types of animal models of choroidal neovascularization (CNV) and retinal neovascularization (RNV). Understanding the pathobiology of…”
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Uveal melanoma by Jager, Martine J., Shields, Carol L., Cebulla, Colleen M., Abdel-Rahman, Mohamed H., Grossniklaus, Hans E., Stern, Marc-Henri, Carvajal, Richard D., Belfort, Rubens N., Jia, Renbing, Shields, Jerry A., Damato, Bertil E.

“…Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. UMs are usually initiated by a mutation in GNAQ or GNA11 , unlike cutaneous…”
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Overrepresentation of human epidermal growth factor receptor 2 positive- and Luminal B breast cancer metastases in the eyes and orbit by Stålhammar, Gustav, Grossniklaus, Hans E.

“…Background Breast cancer is the most common cancer to spread to the choroid and orbit. Depending on a set of prognostic and predictive biomarkers, breast…”
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Therapeutic Options for Retinoblastoma by Mendoza, Pia R, Grossniklaus, Hans E

“…Retinoblastoma is the most common primary intraocular malignancy in children. The management of retinoblastoma is complex and depends on several factors. This…”
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Arylsulfonamide 64B Inhibits Hypoxia/HIF-Induced Expression of c-Met and CXCR4 and Reduces Primary Tumor Growth and Metastasis of Uveal Melanoma by Dong, Lei, You, Shuo, Zhang, Qing, Osuka, Satoru, Devi, Narra S, Kaluz, Stefan, Ferguson, Jalisa H, Yang, Hua, Chen, Guoliang, Wang, Binghe, Grossniklaus, Hans E, Van Meir, Erwin G

“…Uveal melanoma (UM) is the most prevalent and lethal intraocular malignancy in adults. Here, we examined the importance of hypoxia in UM growth and tested the…”
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Estimation of the timing of BAP1 mutation in uveal melanoma progression by Uner, Ogul E., See, Thonnie Rose O., Szalai, Eszter, Grossniklaus, Hans E., Stålhammar, Gustav

“…Uveal melanoma is the most common primary intraocular malignancy. A vast majority of metastasizing tumors have mutations in the BAP1 gene. Here, we investigate…”
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The Biology of Retinoblastoma by Mendoza, Pia R, Grossniklaus, Hans E

“…Retinoblastoma, the most common primary intraocular cancer of childhood, is a malignancy arising in the developing retina. Tumor formation usually begins with…”
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Ophthalmic Pathology: History, Accomplishments, Challenges, and Goals by Grossniklaus, Hans E., MD

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Spontaneous Corneal Clearing after Descemet's Stripping without Endothelial Replacement by Shah, Rupa D., MD, Randleman, J. Bradley, MD, Grossniklaus, Hans E., MD, MBA

“…Purpose To report spontaneous corneal clearing with improved visual acuity and central endothelial cell repopulation after Descemet's stripping without…”
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Multimodal Imaging and Histopathology Features of a Corneal Keloid by Azarcon, Corrina P, Wells, Jill R, Grossniklaus, Hans E

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Orbital Lymphoma—An International Multicenter Retrospective Study by Olsen, Tine Gadegaard, Holm, Frederik, Mikkelsen, Lauge Hjorth, Rasmussen, Peter Kristian, Coupland, Sarah E., Esmaeli, Bita, Finger, Paul T., Graue, Gerardo F., Grossniklaus, Hans E., Honavar, Santosh G., Khong, Jwu Jin, McKelvie, Penelope A., Mulay, Kaustubh, Sjö, Lene Dissing, Vemuganti, Geeta K., Thuro, Bradley A., Heegaard, Steffen

“…To investigate and characterize the clinical features of subtype-specific orbital lymphoma. Retrospective, interventional case series. The study included 7…”
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