Search Results - "Grossi, Giancarlo"

Small Molecule Tyrosine Kinase Inhibitors (TKIs) for Glioblastoma Treatment by Frumento, Davide, Grossi, Giancarlo, Falesiedi, Marta, Musumeci, Francesca, Carbone, Anna, Schenone, Silvia

“…In the last decade, many small molecules, usually characterized by heterocyclic scaffolds, have been designed and synthesized as tyrosine kinase inhibitors…”
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Synthetic Heterocyclic Derivatives as Kinase Inhibitors Tested for the Treatment of Neuroblastoma by Musumeci, Francesca, Cianciusi, Annarita, D'Agostino, Ilaria, Grossi, Giancarlo, Carbone, Anna, Schenone, Silvia

“…In the last few years, small molecules endowed with different heterocyclic scaffolds have been developed as kinase inhibitors. Some of them are being tested at…”
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Insights into RNA-dependent RNA Polymerase Inhibitors as Antiinfluenza Virus Agents by Giacchello, Ilaria, Musumeci, Francesca, D'Agostino, Ilaria, Greco, Chiara, Grossi, Giancarlo, Schenone, Silvia

“…Influenza is a seasonal disease that affects millions of people every year and has a significant economic impact. Vaccines are the best strategy to fight this…”
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Discovery of a Novel Chemo-Type for TAAR1 Agonism via Molecular Modeling by Grossi, Giancarlo, Scarano, Naomi, Musumeci, Francesca, Tonelli, Michele, Kanov, Evgeny, Carbone, Anna, Fossa, Paola, Gainetdinov, Raul R, Cichero, Elena, Schenone, Silvia

“…The search for novel effective TAAR1 ligands continues to draw great attention due to the wide range of pharmacological applications related to TAAR1…”
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An Update on JAK Inhibitors by Musumeci, Francesca, Greco, Chiara, Giacchello, Ilaria, Fallacara, Anna Lucia, Ibrahim, Munjed M, Grossi, Giancarlo, Brullo, Chiara, Schenone, Silvia

“…Janus kinases (JAKs) are a family of non-receptor tyrosine kinases, composed by four members, JAK1, JAK2, JAK3 and TYK2. JAKs are involved in different…”
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Pyrrolo[2,3-d]Pyrimidines as Kinase Inhibitors by Musumeci, Francesca, Sanna, Monica, Grossi, Giancarlo, Brullo, Chiara, Fallacara, Anna Lucia, Schenone, Silvia

“…The pyrrolo[2,3-d]pyrimidine nucleus is a deaza-isostere of adenine, the nitrogenous base of ATP, and is present in many ATP-competitive inhibitors of…”
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Anti-Survival Effect of SI306 and Its Derivatives on Human Glioblastoma Cells by Monteleone, Lorenzo, Marengo, Barbara, Musumeci, Francesca, Grossi, Giancarlo, Carbone, Anna, Valenti, Giulia E., Domenicotti, Cinzia, Schenone, Silvia

“…Glioblastoma (GBM) is the most common adult brain tumor and, although many efforts have been made to find valid therapies, the onset of resistance is the main…”
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Synthesis and in vitro inhibitory activity on human platelet aggregation of novel properly substituted 4-(1-piperazinyl)coumarins by Di Braccio, Mario, Grossi, Giancarlo, Roma, Giorgio, Grazia Signorello, Maria, Leoncini, Giuliana

“…Pursuing our chemical and biological studies in this field, we described the multistep preparation of the new 5-, 6-, or 7-alkoxy and 7-alkoxy-8-methyl…”
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Dreamlike Environments: “Story-living” in Virtual Reality Installations by Giancarlo Grossi

“…This article examines the narrative identity of a new emerging medium, the virtual reality installation. In order to do so, the representation of dream states…”
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Recent Studies on Ponatinib in Cancers Other Than Chronic Myeloid Leukemia by Musumeci, Francesca, Greco, Chiara, Grossi, Giancarlo, Molinari, Alessio, Schenone, Silvia

“…Ponatinib is a third line drug for the treatment of chronic myeloid leukemia patients, especially those that develop the gatekeeper mutation T315I, which is…”
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Pyrazole[3,4-d]pyrimidine derivatives loaded into halloysite as potential CDK inhibitors by Massaro, Marina, Barone, Giampaolo, Barra, Viviana, Cancemi, Patrizia, Di Leonardo, Aldo, Grossi, Giancarlo, Lo Celso, Fabrizio, Schenone, Silvia, Viseras Iborra, Cesar, Riela, Serena

“…[Display omitted] •Nanocomposites based on HNTs/pyrazolo[3,4-d]pyrimidine derivatives were developed.•Kinetic release was performed in physiological pH…”
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Introduction: the image between presence and absence by Grossi, Giancarlo, Pinotti, Andrea

“…Dream images, anticipations of the future, memories of the past, perceptual distortions, delusional hallucinations, cognitions intoxicated by alcohol and drugs…”
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Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma by Musumeci, Francesca, Fallacara, Anna Lucia, Brullo, Chiara, Grossi, Giancarlo, Botta, Lorenzo, Calandro, Pierpaolo, Chiariello, Mario, Kissova, Miroslava, Crespan, Emmanuele, Maga, Giovanni, Schenone, Silvia

“…In the last few years, several pyrrolo-pyrimidine derivatives have been either approved by the US FDA and in other countries for the treatment of different…”
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Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction by D'Agostino, Ilaria, Giacchello, Ilaria, Nannetti, Giulio, Fallacara, Anna Lucia, Deodato, Davide, Musumeci, Francesca, Grossi, Giancarlo, Palù, Giorgio, Cau, Ylenia, Trist, Iuni Margaret, Loregian, Arianna, Schenone, Silvia, Botta, Maurizio

“…The limited treatment options against influenza virus along with the growing public health concerns regarding the continuous emergence of drug-resistant…”
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Exploring An-Icons, Between Media Archaeology, Cultural History, Memory Studies and Contemporary Applications by Ilaria Ampollini, Fabrizia Bandi, Federica Cavaletti, Pietro Conte, Margherita Fontana, Giancarlo Grossi, Andrea Pinotti, Sofia Pirandello, Ilaria Terrenghi

“…The ERC Advanced Grant AN-ICON, coordinated by Andrea Pinotti and hosted by the Department of Philosophy Piero Martinetti of the University of Milan, is…”
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Analogs, formulations and derivatives of imatinib: a patent review by Musumeci, Francesca, Schenone, Silvia, Grossi, Giancarlo, Brullo, Chiara, Sanna, Monica

“…The Bcr-Abl inhibitor imatinib was approved in 2001 for chronic myeloid leukemia therapy, and dramatically changed the lives of patients affected by this…”
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Fine molecular tuning at position 4 of 2H-chromen-2-one derivatives in the search of potent and selective monoamine oxidase B inhibitors by Pisani, Leonardo, Catto, Marco, Nicolotti, Orazio, Grossi, Giancarlo, Di Braccio, Mario, Soto-Otero, Ramon, Mendez-Alvarez, Estefania, Stefanachi, Angela, Gadaleta, Domenico, Carotti, Angelo

“…The effects on the inhibition potencies of monoamine oxidase isoforms A (MAO-A) and B (MAO-B) depending upon changes in the physicochemical properties (size,…”
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1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10H-pyrimido[1,2-a][1,8]naphthyridine-6-carboxamide derivative by Di Braccio, Mario, Grossi, Giancarlo, Alfei, Silvana, Ballabeni, Vigilio, Tognolini, Massimiliano, Flammini, Lisa, Giorgio, Carmine, Bertoni, Simona, Barocelli, Elisabetta

“…A new group of 5-(alkylamino)-9-isopropyl[1,2,4]triazolo[4,3-a][1,8]naphthyridine derivatives bearing a CONHR group at the 6-position (1c–g), designed to…”
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Halloysite Nanotube-Based Delivery of Pyrazolo[3,4-d]pyrimidine Derivatives for Prostate and Bladder Cancer Treatment by Massaro, Marina, Ciani, Rebecca, Grossi, Giancarlo, Cavallaro, Gianfranco, de Melo Barbosa, Raquel, Falesiedi, Marta, Fortuna, Cosimo G., Carbone, Anna, Schenone, Silvia, Sánchez-Espejo, Rita, Viseras, César, Vago, Riccardo, Riela, Serena

“…Background/Objectives: The development of therapies targeting unregulated Src signaling through selective kinase inhibition using small-molecule inhibitors…”
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Introduzione. Fenomeni di generazione e media nell'età contemporanea by Giancarlo Grossi, Myriam Mereu

“…Introduction to the special issue…”
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