Search Results - "Grossel, Martha J."

A Firefly Luciferase Dual Color Bioluminescence Reporter Assay Using Two Substrates To Simultaneously Monitor Two Gene Expression Events by Branchini, Bruce R., Southworth, Tara L., Fontaine, Danielle M., Kohrt, Dawn, Florentine, Catherine M., Grossel, Martha J.

“…Effective methods for monitoring eukaryotic gene expression and regulation based on bioluminescence - the emission of light by living organisms - are well…”
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An enhanced chimeric firefly luciferase-inspired enzyme for ATP detection and bioluminescence reporter and imaging applications by Branchini, Bruce R., Southworth, Tara L., Fontaine, Danielle M., Kohrt, Dawn, Talukder, Munya, Michelini, Elisa, Cevenini, Luca, Roda, Aldo, Grossel, Martha J.

“…Firefly luciferases, which emit visible light in a highly specific ATP-dependent process, have been adapted for a variety of applications, including gene…”
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Red-emitting chimeric firefly luciferase for in vivo imaging in low ATP cellular environments by Branchini, Bruce R., Southworth, Tara L., Fontaine, Danielle M., Kohrt, Dawn, Welcome, Franceine S., Florentine, Catherine M., Henricks, Emma R., DeBartolo, Demetria B., Michelini, Elisa, Cevenini, Luca, Roda, Aldo, Grossel, Martha J.

“…Beetle luciferases have been adapted for live cell imaging where bioluminescence is dependent on the cellular availability of ATP, O2, and added luciferin…”
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Beyond the cell cycle: A new role for Cdk6 in differentiation by Grossel, Martha J., Hinds, Philip W.

“…Over 10 years ago, cdk6 was identified as a new member in a family of vertebrate cdc‐2 related kinases. This novel kinase was found to partner with the D‐type…”
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From Cell Cycle to Differentiation: An Expanding Role for Cdk6 by Grossel, Martha J., Hinds, Philip W.

“…Over ten years ago, cdk6 was identified as a new member in a family of vertebrate cdc-2 related kinases. This novel kinase was found to partner with the D-type…”
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Distinct subcellular distribution of cyclin dependent kinase 6 by Kohrt, Dawn, Crary, Jennifer, Gocheva, Vasilena, Hinds, Philip W., Grossel, Martha J.

“…Several studies have recently reported that the cyclin dependent kinase (cdk) 6 oncogene plays a role in differentiation of a variety of cell types. This novel…”
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CDK6 binds and promotes the degradation of the EYA2 protein by Kohrt, Dawn, Crary, Jennifer, Zimmer, Marc, Patrick, Aaron, Ford, Heide, Hinds, Philip W., Grossel, Martha J.

“…Cyclin-dependent kinase 6 (Cdk6) is a D-Cyclin-activated kinase that is directly involved in driving the cell cycle through inactivation of pRB in G 1 phase…”
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Using the Two-Hybrid Screen in the Classroom Laboratory by Odom, Daniel P, Grossel, Martha J

“…Describes a two-hybrid research project incorporated into a molecular biology course that contains both a lecture section and a laboratory section. (Author/KHR)…”
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Changes in motility, gene expression and actin dynamics: Cdk6-induced cytoskeletal changes associated with differentiation in mouse astrocytes by Slomiany, Peter, Baker, Thomas, Elliott, Emily R., Grossel, Martha J.

“…Cyclin dependent kinase (cdk) 4 and cdk6 have historically been understood to be D‐cyclin kinases that phosphorylate pRb in the nucleus to regulate G1 phase of…”
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Science in the News: A Study of Reporting Genomics by Kua, Eunice, Reder, Michael, Grossel, Martha J.

“…Scientists and academicians in the field of science writing agree that context and method are important components of research to be reported. This ideal is…”
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Expression of cyclin-dependent kinase 6, but not cyclin-dependent kinase 4, alters morphology of cultured mouse astrocytes by ERICSON, Karen K, KRULL, David, SLOMIANY, Peter, GROSSEL, Martha J

“…Disruption of the pRb pathway is a common mechanism in tumor formation. The D-cyclin-associated kinases, cyclin-dependent kinase (cdk) 4 and cdk6, are…”
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cdk6 Can Shorten G1 Phase Dependent upon the N-terminal INK4 Interaction Domain by Grossel, Martha J., Baker, Gregory L., Hinds, Philip W.

“…Deregulated activity of cdk4 or cdk6 can lead to inappropriate cellular proliferation and tumorigenesis accompanied by unchecked inactivation of the…”
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Drosophila Krüppel protein is a transcriptional represser by Licht, Jonathan D, Grossel, Martha J, Figge, James, Hansen, Ulla M

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A yeast two-hybrid system for discerning differential interactions using multiple baits by Hinds, Philip W, Grossel, Martha J, Wang, Hongmei, Gadea, Bedrick, Yeung, Wilbert

“…The yeast two-hybrid system is a powerful genetic technique designed to identify novel protein-protein interactions that were previously limited to detection…”
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Abstract A58: Cdk6 association with a transcriptional coactivator indicates a potential role for this cyclin dependent kinase in regulating differentiation by Crary, Jennifer I., Grossel, Martha J., Hinds, Phil W.

“…Abstract Cdk6 is a well characterized cyclin dependent kinase that regulates the transition from G1 phase to S phase during the cell cycle with the assistance…”
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Expression of Cyclin-Dependent Kinase 6, but not Cyclin-Dependent Kinase 4, Alters Morphology of Cultured Mouse Astrocytes11NSF under CAREER grant #9984454 to Martha J. Grossel by Karen K. Ericson, David Krull, Peter Slomiany, Martha J. Grossel

“…Disruption of the pRb pathway is a common mechanism in tumor formation. The D-cyclin-associated kinases, cyclin-dependent kinase (cdk) 4 and cdk6, are…”
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Functional interaction of a novel cellular protein with the papillomavirus E2 transactivation domain by Breiding, David E., Sverdrup, Francis, Grossel, Martha J., Moscufo, Nicola, Boonchai, Waranya, Androphy, Elliot J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Drosophila Kruppel protein is a transcriptional repressor by Licht, J.D, Grossel, M.J, Figge, J, Hansen, U.M

“…KRUPPEL (Kr), one of the zygotically active Drosophila segmentation genes, is expressed in a restricted domain during the blastoderm stage of embryogenesis and…”
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Genetic Analysis of the Bovine Papillomavirus E2 Transcriptional Activation Domain by Breiding, David E., Grossel, Martha J., Androphy, Elliot J.

“…The bovine papillomavirus type 1 E2 transactivator has a large amino-terminal 215-residue transcriptional activation domain (TAD) that is active…”
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Transcriptional activation function is not required for stimulation of DNA replication by bovine papillomavirus type 1 E2 by Grossel, M.J. (Tufts University, Boston, MA.), Sverdrup, F, Breiding, D.E, Androphy, E.J

“…Bovine papillomavirus type 1 replication was previously shown to require both the E1 initiator protein and the E2 transactivator protein. We show here that E1,…”
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