Search Results - "Grosse, Gerrit M."
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Arginine Derivatives in Cerebrovascular Diseases: Mechanisms and Clinical Implications
Published in International journal of molecular sciences (05-03-2020)“…The amino acid L-arginine serves as substrate for the nitric oxide synthase which is crucial in vascular function and disease. Derivatives of arginine, such as…”
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Unraveling Mechanisms of Cryptogenic Stroke at the Genetic Level: A Systematic Literature Review
Published in Journal of the American Heart Association (01-08-2023)“…Background A substantial proportion of ischemic strokes remain cryptogenic, which has important implications for secondary prevention. Identifying genetic…”
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Interplay between driveline infection, vessel wall inflammation, cerebrovascular events and mortality in patients with left ventricular assist device
Published in Scientific reports (29-10-2023)“…In patients with left ventricular assist device (LVAD), infections and thrombotic events represent severe complications. We investigated device-specific local…”
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4
Clinical and paraclinical characteristics of optic neuritis in the context of the McDonald criteria 2017
Published in Scientific reports (27-03-2024)“…Optic neuritis is often an initial symptom in multiple sclerosis (MS) or clinically isolated syndrome (CIS), yet comprehensive studies using the 2017 McDonald…”
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5
Identification of a rare SEPT9 variant in a family with autosomal dominant Charcot-Marie-Tooth disease
Published in BMC medical genetics (02-03-2020)“…Charcot-Marie-Tooth disease (CMT) is one of the most commonly inherited neurological disorders. A growing number of genes, involved in glial and neuronal…”
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Circulating Inflammatory Biomarkers in Early Prediction of Stroke-Associated Infections
Published in International journal of molecular sciences (09-11-2022)“…(1) Background: Patients with acute ischaemic stroke (AIS) are at high risk for stroke-associated infections (SAIs). We hypothesised that increased…”
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Endovascular Treatment of Acute Ischemic Stroke in Clinical Practice: Analysis of Workflow and Outcome in a Tertiary Care Center
Published in Frontiers in neurology (07-06-2021)“…Background and Purpose: Pre- and intra-hospital workflow in mechanical recanalization of large cervicocephalic arteries in patients with acute ischemic stroke…”
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Distinct systemic cytokine networks in symptomatic and asymptomatic carotid stenosis
Published in Scientific reports (15-12-2020)“…Inflammatory processes are crucial in atherosclerosis and atherothrombosis. This study aimed to identify a cytokine-pattern that is associated with…”
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Septal total atrial conduction time for prediction of atrial fibrillation in embolic stroke of unknown source: a pilot study
Published in Clinical research in cardiology (01-02-2020)“…Background Subclinical atrial fibrillation (AF) is the underlying cause in a relevant part of patients with embolic stroke of unknown source (ESUS). This pilot…”
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Insights Into Immunothrombotic Mechanisms in Acute Stroke due to Vaccine-Induced Immune Thrombotic Thrombocytopenia
Published in Frontiers in immunology (10-05-2022)“…During the COVID-19 pandemic, vaccination is the most important countermeasure. Pharmacovigilance concerns however emerged with very rare, but potentially…”
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ADAMTS-13 activity in stroke of known and unknown cause: Relation to vascular risk factor burden
Published in Frontiers in neurology (10-01-2023)“…The identification of the underlying mechanism in ischemic stroke has important implications for secondary prevention. A disintegrin and metalloprotease with a…”
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Plasma Dimethylarginine Levels and Carotid Intima-Media Thickness are related to Atrial Fibrillation in Patients with Embolic Stroke
Published in International journal of molecular sciences (09-02-2019)“…A relevant part of embolic strokes of undetermined source (ESUS) is assumed to be due to non-detected atrial fibrillation (AF). In this study, we aimed to…”
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13
Monocyte Subsets and Related Chemokines in Carotid Artery Stenosis and Ischemic Stroke
Published in International journal of molecular sciences (23-03-2016)“…Carotid stenosis (CS) is an important cause of ischemic stroke. However, reliable markers for the purpose of identification of high-risk, so-called vulnerable…”
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14
Circulating fibroblast activation protein α is reduced in acute ischemic stroke
Published in Frontiers in cardiovascular medicine (07-12-2022)“…Fibroblast activation protein α (FAP), a membrane glycoprotein with dipeptidyl-peptidase and collagenase properties, is expressed in atherosclerotic plaques…”
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15
Circulating microRNAs in Symptomatic and Asymptomatic Carotid Stenosis
Published in Frontiers in neurology (24-11-2021)“…Specific microRNAs (miRs) have been implicated in the pathophysiology of atherosclerosis and may represent interesting diagnostic and therapeutic targets in…”
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Advancement of door-to-needle times in acute stroke treatment after repetitive process analysis: never give up
Published in Therapeutic advances in neurological disorders (2022)“…Background: In acute ischemic stroke, timely treatment is of utmost relevance. Identification of delaying factors and knowledge about challenges concerning…”
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Echocardiographic Parameters to Predict Atrial Fibrillation in Clinical Routine-The EAHsy-AF Risk Score
Published in Frontiers in cardiovascular medicine (08-03-2022)“…Echocardiographic parameters representing impaired left atrial (LA) function and remodeling are of high value to predict atrial fibrillation (AF). This study…”
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Sex-Specific Risk Factors of Nonstenotic Carotid Plaque in Embolic Stroke of Unknown Source: A Case-Control Study
Published in Stroke (1970) (01-02-2024)“…Many ischemic strokes are diagnosed as embolic strokes of undetermined source (ESUS). Recent evidence suggests that nonstenotic carotid plaque (nsCP) may be a…”
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Endogenous Deoxyribonuclease Activity and Cell-Free Deoxyribonucleic Acid in Acute Ischemic Stroke: A Cohort Study
Published in Stroke (1970) (01-04-2022)“…Cell-free DNA (cfDNA) and endogenous deoxyribonuclease activity are opposing mediators and might influence the inflammatory response following acute ischemic…”
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Long‐Term Follow‐Up of Neuropsychiatric Symptoms After Sustained Virological Response to Interferon‐Free and Interferon‐Based Hepatitis C Virus Treatment
Published in Journal of viral hepatitis (06-11-2024)“…ABSTRACT Chronic hepatitis C virus (HCV) infection can be associated with neuropsychiatric symptoms like fatigue and cognitive impairment, independent of the…”
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