Search Results - "Gross, WL"

Netting neutrophils in autoimmune small-vessel vasculitis by Kessenbrock, Kai, Jenne, Dieter E, Krumbholz, Markus, Schönermarck, Ulf, Back, Walter, Gross, Wolfgang L, Werb, Zena, Gröne, Hermann-Josef, Brinkmann, Volker

“…Small-vessel vasculitis (SVV) is a chronic autoinflammatory condition linked to antineutrophil cytoplasm autoantibodies (ANCAs). Here we show that chromatin…”
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Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized trial by de Groot, Kirsten, Harper, Lorraine, Jayne, David R W, Flores Suarez, Luis Felipe, Gregorini, Gina, Gross, Wolfgang L, Luqmani, Rashid, Pusey, Charles D, Rasmussen, Niels, Sinico, Renato A, Tesar, Vladimir, Vanhille, Philippe, Westman, Kerstin, Savage, Caroline O S

“…Current therapies for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis are limited by toxicity. To compare pulse cyclophosphamide with daily…”
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Efficacy of transbronchial biopsy in pulmonary vaculitides by Schnabel, A, Holl-Ulrich, K, Dalhoff, K, Reuter, M, Gross, WL

“…This study was performed to determine the value of transbronchial biopsy (TBB) in patients with antineutrophil cytoplasmic antibody (ANCA)-associated…”
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Effectiveness of TNF‐α blockade with infliximab in refractory Wegener's granulomatosis by Lamprecht, P., Voswinkel, J., Lilienthal, T., Nolle, B., Heller, M., Gross, W. L., Gause, A.

“…Objective. To study the effect of the chimeric monoclonal anti‐tumour necrosis factor α (TNF‐α) antibody infliximab in the induction of remission in six…”
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Proinflammatory Cytokines and Autoimmunity in Churg-Strauss Syndrome by HELLMICH, B., CSERNOK, E., GROSS, W. L.

“…: Churg‐Strauss syndrome (CSS) belongs to the antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitides and is further characterized by severe…”
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Correlation of serum level of high mobility group box 1 with the burden of granulomatous inflammation in granulomatosis with polyangiitis (Wegener's) by Henes, F O, Chen, Y, Bley, T A, Fabel, M, Both, M, Herrmann, K, Csernok, E, Gross, W L, Moosig, F

“…To investigate the correlation of serum levels of high mobility group box 1 (HMGB1) with the extent of granulomatous inflammation in granulomatosis with…”
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Interstitial lung disease in polymyositis and dermatomyositis: Clinical course and response to treatment by Schnabel, Armin, Reuter, Michael, Biederer, Jürgen, Richter, Christiane, Gross, Wolfgang L.

“…Objectives: To assess the prevalence, clinical characteristics, and treatment options of patients with interstitial lung disease (ILD) in polymyositis and…”
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Peripheral Blood and Granuloma CD4 +CD28 − T Cells Are a Major Source of Interferon-γ and Tumor Necrosis Factor-α in Wegener’s Granulomatosis by Komocsi, Andras, Lamprecht, Peter, Csernok, Elena, Mueller, Antje, Holl-Ulrich, Konstanze, Seitzer, Ulrike, Moosig, Frank, Schnabel, Armin, Gross, Wolfgang Ludwig

“…To elucidate whether the fraction of CD28 − T cells within the CD4 + T-cell population is a major source of Th1-like and proinflammatory cytokine production…”
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Maintenance of remission with leflunomide in Wegener's granulomatosis by Metzler, C., Fink, C., Lamprecht, P., Gross, W. L., Reinhold-Keller, E.

“…Objective. To investigate the safety and efficacy of leflunomide plus low-dose prednisolone for the maintenance of remission in Wegener's granulomatosis (WG)…”
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Association of UCP2 −866 G A polymorphism with chronic inflammatory diseases by Yu, X, Wieczorek, S, Franke, A, Yin, H, Pierer, M, Sina, C, Karlsen, T H, Boberg, K M, Bergquist, A, Kunz, M, Witte, T, Gross, W L, Epplen, J T, Alarcón-Riquelme, M E, Schreiber, S, Ibrahim, S M

“…We reported earlier that two mitochondrial gene polymorphisms, UCP2 –866 G/A (rs659366) and mtDNA nt13708 G/A (rs28359178), are associated with multiple…”
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Successful treatment of refractory anterior scleritis in primary Sjögren’s syndrome with rituximab by Ahmadi-Simab, K, Lamprecht, P, Nölle, B, Ai, M, Gross, W L

“…DISCUSSION Killing of CD20 positive cells mediated by rituximab is caused by several mechanisms, including complement dependent cytotoxicity, antibody…”
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Churg-Strauss syndrome: update on recent developments by Gross, W L

“…Churg-Strauss syndrome (CSS) is a form of primary vasculitis characterized by allergy and angiitis. In the organ systems involved (lung, heart, peripheral…”
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New genomic region for Wegener's granulomatosis as revealed by an extended association screen with 202 apoptosis-related genes by JAGIELLO, Peter, GENCIK, Martin, ARNING, Larissa, WIECZOREK, Stefan, KUNSTMANN, Erdmute, CSERNOK, Elena, GROSS, Wolfgang L, EPPLEN, Joerg T

“…Wegener's granulomatosis (WG) is a systemic disease with complex genetic background. It is characterized by necrotizing granulomatous inflammation of the upper…”
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Rituximab induces remission in refractory HCV associated cryoglobulinaemic vasculitis by Lamprecht, P, Lerin-Lozano, C, Merz, H, Dennin, R H, Gause, A, Voswinkel, J, Peters, S O, Gutzeit, O, Arlt, A C, Solbach, W, Gross, W L

“…Objectives: To report the successful induction of remission with the monoclonal anti-CD20 antibody rituximab in a patient with hepatitis C virus (HCV)…”
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High white blood cell count in patients with giant cell arteritis predicts an increased risk of stenosis in upper extremity arteries by Both, M, Schulte, K, Moosig, F, Fritzer, E, Gross, Wl, Heller, M, Biederer, J

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Advances in the therapy of Wegenerʼs granulomatosis by Hellmich, Bernhard, Lamprecht, Peter, Gross, Wolfgang L

“…PURPOSE OF REVIEWIn the past, recommendations for the treatment of Wegenerʼs granulomatosis were primarily based on findings reported from open-label clinical…”
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Nomenclature of systemic vasculitides. Proposal of an international consensus conference by Jennette, J C, Falk, R J, Andrassy, K, Bacon, P A, Churg, J, Gross, W L, Hagen, E C, Hoffman, G S, Hunder, G G, Kallenberg, C G

“…The following are some of the conclusions and proposals made at the Chapel Hill Consensus Conference on the Nomenclature of Systemic Vasculitis. 1. Although…”
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Churg Strauss syndrome--successful induction of remission with methotrexate and unexpected high cardiac and pulmonary relapse ratio during maintenance treatment by Metzler, C, Hellmich, B, Gause, A, Gross, W L, de Groot, K

“…To examine the safety and efficacy of methotrexate (MTX) plus low-dose prednisolone for induction of remission in non life- or organ-threatening courses and…”
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Interferon-α treatment of Four patients with the Churg-Strauss syndrome by TATSIS, E, SCHNABEL, A, GROSS, W. L

“…Interferon-alpha is reported to have a beneficial effect on patients with the idiopathic hypereosinophilic syndrome. To study the effect of interferon-alpha on…”
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Correlation between HRCT findings, pulmonary function tests and bronchoalveolar lavage cytology in interstitial lung disease associated with rheumatoid arthritis by Biederer, J, Schnabel, A, Muhle, C, Gross, W L, Heller, M, Reuter, M

“…A prospective study correlating high-resolution computed tomography (HRCT), lung function tests (PFT) and bronchoalveolar lavage (BAL) cytology in patients…”
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