Search Results - "Gross, Sarah"

Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis by Almad, Akshata A., Doreswamy, Arpitha, Gross, Sarah K., Richard, Jean-Philippe, Huo, Yuqing, Haughey, Norman, Maragakis, Nicholas J.

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor neurons in the CNS. Astrocytes play a critical…”
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Cx43 hemichannels contribute to astrocyte-mediated toxicity in sporadic and familial ALS by Almad, Akshata A, Taga, Arens, Joseph, Jessica, Gross, Sarah K, Welsh, Connor, Patankar, Aneesh, Richard, Jean-Philippe, Rust, Khalil, Pokharel, Aayush, Plott, Caroline, Lillo, Mauricio, Dastgheyb, Raha, Eggan, Kevin, Haughey, Norman, Contreras, Jorge E, Maragakis, Nicholas J

“…Connexin 43 (Cx43) gap junctions and hemichannels mediate astrocyte intercellular communication in the central nervous system under normal conditions and…”
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Managing family dynamics when caring for older adults by Gross, Sarah J.

“…Caring for older patients with neurocognitive disorders can be challenging, especially when family members disagree regarding optimal care. This article…”
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Role of Human‐Induced Pluripotent Stem Cell‐Derived Spinal Cord Astrocytes in the Functional Maturation of Motor Neurons in a Multielectrode Array System by Taga, Arens, Dastgheyb, Raha, Habela, Christa, Joseph, Jessica, Richard, Jean‐Philippe, Gross, Sarah K., Lauria, Giuseppe, Lee, Gabsang, Haughey, Norman, Maragakis, Nicholas J.

“…The ability to generate human‐induced pluripotent stem cell (hiPSC)‐derived neural cells displaying region‐specific phenotypes is of particular interest for…”
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Focal and dose-dependent neuroprotection in ALS mice following AAV2-neurturin delivery by Gross, Sarah K., Shim, Bo Sung, Bartus, Raymond T., Deaver, Dan, McEachin, Zachary, Bétourné, Alexandre, Boulis, Nicholas M., Maragakis, Nicholas J.

“…Neurotrophic factors as candidates for ALS therapeutics have previously been studied in the context of attempts to slow disease progression. For a variety of…”
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Exploring P2X7 receptor antagonism as a therapeutic target for neuroprotection in an hiPSC motor neuron model by Johns, Alexandra E, Taga, Arens, Charalampopoulou, Andriana, Gross, Sarah K, Rust, Khalil, McCray, Brett A, Sullivan, Jeremy M, Maragakis, Nicholas J

“…ATP is present in negligible concentrations in the interstitium of healthy tissues but accumulates to significantly higher concentrations in an inflammatory…”
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Altered astrocytic expression of TDP-43 does not influence motor neuron survival by Haidet-Phillips, Amanda M., Gross, Sarah K., Williams, Timothy, Tuteja, Alisha, Sherman, Alex, Ko, Myungsung, Jeong, Yun H., Wong, Philip C., Maragakis, Nicholas J.

“…The role of glia as a contributing factor to motor neuron (MN) death in amyotrophic lateral sclerosis (ALS) is becoming increasingly appreciated. However, most…”
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Cingulo-opercular control network and disused motor circuits joined in standby mode by Newbold, Dillan J., Gordon, Evan M., Laumann, Timothy O., Seider, Nicole A., Montez, David F., Gross, Sarah J., Zheng, Annie, Nielsen, Ashley N., Hoyt, Catherine R., Hampton, Jacqueline M., Ortega, Mario, Adeyemo, Babatunde, Miller, Derek B., Van, Andrew N., Marek, Scott, Schlaggar, Bradley L., Carter, Alexandre R., Kay, Benjamin P., Greene, Deanna J., Raichle, Marcus E., Petersen, Steven E., Snyder, Abraham Z., Dosenbach, Nico U. F.

“…Whole-brain resting-state functional MRI (rs-fMRI) during 2 wk of upper-limb casting revealed that disused motor regions became more strongly connected to the…”
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Serial in vivo imaging of transplanted allogeneic neural stem cell survival in a mouse model of amyotrophic lateral sclerosis by Srivastava, Amit K., Gross, Sarah K., Almad, Akshata A., Bulte, Camille A., Maragakis, Nicholas J., Bulte, Jeff W.M.

“…Neural stem cells (NSCs) are being investigated as a possible treatment for amyotrophic lateral sclerosis (ALS) through intraspinal transplantation, but no…”
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Human glial progenitor engraftment and gene expression is independent of the ALS environment by Haidet-Phillips, Amanda M., Doreswamy, Arpitha, Gross, Sarah K., Tang, Xiaopei, Campanelli, James T., Maragakis, Nicholas J.

“…Although Amyotrophic Lateral Sclerosis (ALS) is a motor neuron disease, basic research studies have highlighted that astrocytes contribute to the disease…”
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Quercetin reduces illness but not immune perturbations after intensive exercise by NIEMAN, David C, HENSON, Dru A, MCANULTY, Lisa S, MAYER, Eugene P, GROSS, Sarah J, JENKINS, David P, DAVIS, J. Mark, MURPHY, E. Angela, CARMICHAEL, Martin D, DUMKE, Charles L, UTTER, Alan C, MCANULTY, Steven R

“…To investigate the effects of quercetin supplementation on incidence of upper respiratory tract infections (URTI) and exercise-induced changes in immune…”
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Quercetin's influence on exercise-induced changes in plasma cytokines and muscle and leukocyte cytokine mRNA by Nieman, David C, Henson, Dru A, Davis, J. Mark, Angela Murphy, E, Jenkins, David P, Gross, Sarah J, Carmichael, Martin D, Quindry, John C, Dumke, Charles L, Utter, Alan C, McAnulty, Steven R, McAnulty, Lisa S, Triplett, N. Travis, Mayer, Eugene P

“…1 Departments of Health, Leisure, and Exercise Science, and Biology, Appalachian State University, Boone, North Carolina; and 2 Department of Exercise Science,…”
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Gene Profiling of Human Induced Pluripotent Stem Cell‐Derived Astrocyte Progenitors Following Spinal Cord Engraftment by Haidet-Phillips, Amanda M., Roybon, Laurent, Gross, Sarah K., Tuteja, Alisha, Donnelly, Christopher J., Richard, Jean-Philippe, Ko, Myungsung, Sherman, Alex, Eggan, Kevin, Henderson, Christopher E., Maragakis, Nicholas J.

“…This study investigated whether human induced pluripotent stem cell (hiPSC)‐derived astrocyte progenitors could be engrafted to the rodent spinal cord and how…”
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Muscle damage is linked to cytokine changes following a 160-km race by Nieman, David C., Dumke, Charles L., Henson, Dru A., McAnulty, Steven R., Gross, Sarah J., Lind, Robert H.

“…Muscle damage and perceived soreness following the 160-km Western States Endurance Run were related to changes in plasma cytokines and use of nonsteroidal…”
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β-Glucan, Immune Function, and Upper Respiratory Tract Infections in Athletes by NIEMAN, David C, HENSON, Dru A, MCMAHON, Mary, WRIEDEN, Jenna L, DAVIS, J. Mark, MURPHY, E. Angela, GROSS, Sarah J, MCANULTY, Lisa S, DUMKE, Charles L

“…This study investigated the effects of oat beta-glucan (BG) supplementation on chronic resting immunity, exercise-induced changes in immune function, and…”
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Empirical basis of the Questionnaire for Crying, Feeding and Sleeping by Gross, Sarah, Reck, Corinna, Thiel-Bonney, Consolata, Cierpka, Manfred

“…The Questionnaire for Crying, Feeding and Sleeping of an infant, constructed based on theory and factor analysis, is assessed for internal consistency,…”
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Perfluorocarbon Labeling of Human Glial‐Restricted Progenitors for 19F Magnetic Resonance Imaging by Richard, Jean‐Philippe, Hussain, Uzma, Gross, Sarah, Taga, Arens, Kouser, Mehreen, Almad, Akshata, Campanelli, James T., Bulte, Jeff W.M., Maragakis, Nicholas J.

“…One of the fundamental limitations in assessing potential efficacy in Central Nervous System (CNS) transplantation of stem cells is the capacity for monitoring…”
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Feasibility and Impact Assessment of a Food Insecurity Protocol in a Large Urban Pediatric Primary Care Network by Kim, Noah, Fischer, Laura, Gross, Sarah Haley, Weissman, Mark, Essel, Kofi

“…In 2022, 1 in 6 households with children experienced food insecurity (FI) in the United States. The negative impact of FI on child health is well documented…”
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Successive bouts of cycling stimulates genes associated with mitochondrial biogenesis by Dumke, Charles L., Mark Davis, J., Angela Murphy, E., Nieman, David C., Carmichael, Martin D., Quindry, John C., Travis Triplett, N., Utter, Alan C., Gross Gowin, Sarah J., Henson, Dru A., McAnulty, Steven R., McAnulty, Lisa S.

“…Exercise increases mRNA for genes involved in mitochondrial biogenesis and oxidative enzyme capacity. However, little is known about how these genes respond to…”
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Muscle cytokine mRNA changes after 2.5 h of cycling : Influence of carbohydrate by NIEMAN, David C, DAVIS, J. Mark, MCANULTY, Lisa S, TRIPLETT, N. Travis, HENSON, Dru A, GROSS, Sarah J, DUMKE, Charles L, UTTER, Alan C, VINCI, Debra M, CARSON, James A, BROWN, Adrienne, MCANULTY, Steve R

“…To study the effect of carbohydrate compared to placebo ingestion on plasma cytokines and muscle cytokine mRNA following 2.5 h of intensive cycling in 15…”
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