Search Results - "Gross, Mitchell E"
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Impact of resistance training on body composition and metabolic syndrome variables during androgen deprivation therapy for prostate cancer: a pilot randomized controlled trial
Published in BMC cancer (03-04-2018)“…Prostate cancer patients on androgen deprivation therapy (ADT) experience adverse effects such as lean mass loss, known as sarcopenia, fat gain, and changes in…”
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2
Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells
Published in PloS one (01-08-2014)“…Timely characterization of a cancer's evolution is required to predict treatment efficacy and to detect resistance early. High content analysis of single…”
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3
Detection of Androgen Receptor Mutations in Circulating Tumor Cells in Castration-Resistant Prostate Cancer
Published in Clinical chemistry (Baltimore, Md.) (01-09-2010)“…Coding mutations in the AR (androgen receptor) gene have been identified in tissue samples from patients with advanced prostate cancer and represent a possible…”
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4
Monitoring dynamic cytotoxic chemotherapy response in castration-resistant prostate cancer using plasma cell-free DNA (cfDNA)
Published in BMC research notes (15-05-2019)“…Cell-free DNA (cfDNA) is an attractive cancer biomarker, as it is thought to reflect a component of the underlying genetic makeup of the tumor and is readily…”
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5
Prospective Evaluation of 18F-NaF and 18F-FDG PET/CT in Detection of Occult Metastatic Disease in Biochemical Recurrence of Prostate Cancer
Published in Clinical nuclear medicine (01-07-2012)“…PURPOSEThis study aimed to perform a prospective evaluation of F-NaF and F-FDG PET/CT in the detection of occult metastatic disease in men with prostate cancer…”
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6
Automated analysis of co-localized protein expression in histologic sections of prostate cancer
Published in PloS one (26-05-2017)“…An automated approach based on routinely-processed, whole-slide immunohistochemistry (IHC) was implemented to study co-localized protein expression in tissue…”
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7
Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression
Published in PloS one (18-02-2015)“…Prostate cancer (PCa) is the second-leading cause of cancer-related mortality, after lung cancer, in men from developed countries. In its early stages, primary…”
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8
Effect of Periodized Resistance Training on Skeletal Muscle During Androgen Deprivation Therapy for Prostate Cancer: A Pilot Randomized Trial
Published in Integrative cancer therapies (2021)“…Purpose: Prostate cancer survivors (PCS) receive androgen deprivation therapy (ADT) as treatment for recurrent cancer, yet ADT is associated with loss of…”
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9
Immune biomarkers associated with COVID-19 disease severity in an urban, hospitalized population
Published in Practical laboratory medicine (01-08-2023)“…We sought to identify immune biomarkers associated with severe Coronavirus disease 2019 (COVID-19) in patients admitted to a large urban hospital during the…”
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10
Salvage ablative therapy in prostate cancer: International multidisciplinary consensus on trial design
Published in Urologic oncology (01-11-2015)“…Abstract Introduction Salvage ablative therapy (SAT) has been developed as a form of localized treatment for localized recurrence of prostate cancers following…”
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11
CCR2-targeted micelles for anti-cancer peptide delivery and immune stimulation
Published in Journal of controlled release (10-01-2021)“…Signaling between the CC chemokine receptor 2 (CCR2) with its ligand, monocyte chemoattractant protein-1 (MCP-1) promotes cancer progression by directly…”
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12
Effect of Monoamine oxidase A (MAOA) inhibitors on androgen‐sensitive and castration‐resistant prostate cancer cells
Published in The Prostate (01-05-2019)“…Background Monoamine oxidase A (MAOA) is best known for its role in neuro‐transmitter regulation. Monoamine oxidase inhibitors are used to treat atypical…”
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13
Focal Cryotherapy for Clinically Unilateral, Low-Intermediate Risk Prostate Cancer in 73 Men with a Median Follow-Up of 3.7 Years
Published in European urology (01-07-2012)“…Abstract Background Evolution of cryotherapy for prostate cancer is likely to result in parenchyma-sparing modifications adjacent to the urethra and…”
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14
Loss of MAOA in epithelia inhibits adenocarcinoma development, cell proliferation and cancer stem cells in prostate
Published in Oncogene (01-09-2018)“…Monoamine oxidase A (MAOA) is a mitochondrial enzyme, which degrades monoamine neurotransmitters and dietary amines and produces H 2 O 2 . Recent studies have…”
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15
Blood-based gene expression profiling in castrate-resistant prostate cancer
Published in BMC medicine (14-09-2015)“…Castrate-resistant prostate cancer (CRPC), the most life-threatening form of prostate cancer, has recently been the focus of many successful new treatments…”
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16
Androgen receptor in cancer-associated fibroblasts influences stemness in cancer cells
Published in Endocrine-related cancer (01-04-2017)“…Androgen receptor (AR) regulation pathways are essential for supporting the growth and survival of prostate cancer cells. Recently, sub-populations of prostate…”
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Phase 2 trial of monoamine oxidase inhibitor phenelzine in biochemical recurrent prostate cancer
Published in Prostate cancer and prostatic diseases (01-03-2021)“…Purpose Monoamine oxidase A (MAOA) influences prostate cancer growth and metastasis in pre-clinical models. We examined effects of phenelzine (a monoamine…”
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18
Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis
Published in Oncogene (01-04-2019)“…Anterior gradient 2 (AGR2) is a member of the protein disulfide isomerase (PDI) family, which plays a role in the regulation of protein homeostasis and the…”
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19
Synthesis and anti-cancer potential of potent peripheral MAOA inhibitors designed to limit blood:brain penetration
Published in Bioorganic & medicinal chemistry (07-09-2023)“…[Display omitted] •Clorgyline is an irreversible monoamine oxidase A inhibitor used clinically as an antidepressant.•Previous studies show that clorgyline and…”
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Intolerance of uncertainty, cognitive complaints, and cancer-related distress in prostate cancer survivors
Published in Psycho-oncology (Chichester, England) (01-02-2015)“…Objective Prostate cancer survivors have reported cognitive complaints following treatment, and these difficulties may be associated with survivors' ongoing…”
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