Search Results - "Gross, Mackensie"
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The human malaria parasite Plasmodium falciparum can sense environmental changes and respond by antigenic switching
Published in Proceedings of the National Academy of Sciences - PNAS (25-04-2023)“…The primary antigenic and virulence determinant of the human malaria parasite is a variant surface protein called PfEMP1. Different forms of PfEMP1 are encoded…”
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A coordinated transcriptional switching network mediates antigenic variation of human malaria parasites
Published in eLife (14-12-2022)“…Malaria parasites avoid immune clearance through their ability to systematically alter antigens exposed on the surface of infected red blood cells. This is…”
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Evolution of transcriptional control of antigenic variation and virulence in human and ape malaria parasites
Published in BMC ecology and evolution (08-07-2021)“…The most severe form of human malaria is caused by the protozoan parasite Plasmodium falciparum. This unicellular organism is a member of a subgenus of…”
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The Role of the Histone Methyltransferase PfSET10 in Antigenic Variation by Malaria Parasites: a Cautionary Tale
Published in mSphere (03-02-2021)“…The virulence of the malaria parasite is due in large part to its ability to avoid immune destruction through antigenic variation. This results from changes in…”
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Prenatal Immunization to Prevent Viral Disease Outcomes During Pregnancy and Early Life
Published in Frontiers in virology (online) (19-05-2022)“…Pregnancy significantly elevates the risk of developing severe viral diseases, which can have a detrimental effect on fetal development and increases maternal…”
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SARS-CoV-2 Vaccine-Elicited Antibody Responses in Breastmilk
Published in The Journal of immunology (1950) (01-05-2023)“…SARS-CoV-2 mRNA-LNP immunizations significantly reduce severe COVID19. However, our understanding of the immune response within the context of pregnancy and…”
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SARS-CoV-2 Vaccine Elicited Antibody Responses in Human Milk
Published in Journal of the Pediatric Infectious Diseases Society (06-09-2024)Get full text
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