Search Results - "Gross, Lisa K"

Shiga Toxin 2 Affects the Central Nervous System through Receptor Globotriaosylceramide Localized to Neurons by Obata, Fumiko, Tohyama, Koujiro, Bonev, Adrian D., Kolling, Glynis L., Keepers, Tiffany R., Gross, Lisa K., Nelson, Mark T., Sato, Shigehiro, Obrig, Tom G.

“…Affinity-purified Shiga toxin (Stx) 2 given intraperitoneally to mice caused weight loss and hind-limb paralysis followed by death. Globotriaosylceramide…”
Get full text

Monocyte Chemoattractant Protein 1, Macrophage Inflammatory Protein 1α, and RANTES Recruit Macrophages to the Kidney in a Mouse Model of Hemolytic-Uremic Syndrome by Keepers, Tiffany R, Gross, Lisa K, Obrig, Tom G

“…The macrophage has previously been implicated in contributing to the renal inflammation associated with hemolytic-uremic syndrome (HUS). However, there is…”
Get full text

Shiga Toxin 2 Targets the Murine Renal Collecting Duct Epithelium by Psotka, Mitchell A, Obata, Fumiko, Kolling, Glynis L, Gross, Lisa K, Saleem, Moin A, Satchell, Simon C, Mathieson, Peter W, Obrig, Tom G

“…Hemolytic-uremic syndrome (HUS) caused by Shiga toxin-producing Escherichia coli infection is a leading cause of pediatric acute renal failure. Bacterial…”
Get full text

CXCL1/KC and CXCL2/MIP-2 Are Critical Effectors and Potential Targets for Therapy of Escherichia coli O157:H7-Associated Renal Inflammation by Roche, James K, Keepers, Tiffany R, Gross, Lisa K, Seaner, Regina M, Obrig, Tom G

“…Neutrophilia is a characteristic of hemolytic uremic syndrome caused by Shiga toxin (Stx2)-producing Escherichia coli . However, the role of neutrophils in the…”
Get full text

Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model by Roche, James K, Stone, Matthew K, Gross, Lisa K, Lindner, Matthew, Seaner, Regina, Pincus, Seth H, Obrig, Tom G

“…Effects in the liver of fatal intoxication with the binary toxin ricin are unclear. We report a robust neutrophil influx into the liver of C57BL/6 mice after…”
Get full text

A murine model of HUS : Shiga toxin with lipopolysaccharide mimics the renal damage and physiologic response of human disease by KEEPERS, Tiffany R, PSOTKA, Mitchell A, GROSS, Lisa K, OBRIG, Tom G

“…Hemolytic uremic syndrome (HUS), which is caused by Shiga toxin-producing Escherichia coli infection, is the leading cause of acute renal failure in children…”
Get full text

Immunohistologic techniques for detecting the glycolipid Gb(3) in the mouse kidney and nervous system by Kolling, Glynis L, Obata, Fumiko, Gross, Lisa K, Obrig, Tom G

“…Shiga toxin-producing Escherichia coli causes hemolytic uremic syndrome, a constellation of disorders that includes kidney failure and central nervous system…”
Get full text

Immunohistologic techniques for detecting the glycolipid Gb3 in the mouse kidney and nervous system by Kolling, Glynis L., Obata, Fumiko, Gross, Lisa K., Obrig, Tom G.

“…Shiga toxin-producing Escherichia coli causes hemolytic uremic syndrome, a constellation of disorders that includes kidney failure and central nervous system…”
Get full text

CXCL 1/KC and CXCL2/MIP-2 are critical effectors and potential targets for therapy of Escherichia coli O157:H7-associated renal inflammation by ROCHE, James K, KEEPERS, Tiffany R, GROSS, Lisa K, SEANER, Regina M, OBRIG, Tom G

Get full text

Shiga Toxin 2 Affects the Central Nervous System Through Receptor Gb3 Localized to Neurons by Obata, Fumiko, Tohyama, Koujiro, Bonev, Adrian D., Kolling, Glynis L., Keepers, Tiffany R., Gross, Lisa K., Nelson, Mark T., Sato, Shigehiro, Obrig, Tom G.

“…Affinity purified Shiga toxin 2 (Stx2) i.p. to mice caused weight loss and hind limb paralysis followed by death. Globotriaosylceramide (Gb 3 ), the receptor…”
Get full text