Search Results - "Gross, J D"
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HP1 reshapes nucleosome core to promote phase separation of heterochromatin
Published in Nature (London) (01-11-2019)“…Heterochromatin affects genome function at many levels. It enables heritable gene repression, maintains chromosome integrity and provides mechanical rigidity…”
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In Vivo Pulp Temperature Changes During Class V Cavity Preparation and Resin Composite Restoration in Premolars
Published in Operative dentistry (01-07-2021)“…This in vivo study evaluated the influence of the sequence of all restorative steps during Class V preparation and restoration in human premolars on pulp…”
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Reduction of GPSM3 expression akin to the arthritis-protective SNP rs204989 differentially affects migration in a neutrophil model
Published in Genes and immunity (01-09-2016)“…G Protein Signaling Modulator-3 (GPSM3) is a leukocyte-specific regulator of G protein-coupled receptors (GPCRs), which binds inactivated Gα i ·GDP subunits…”
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Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes
Published in Diabetes (New York, N.Y.) (01-04-1999)“…Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. M Y Donath , D J Gross , E Cerasi and N…”
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Impaired beta-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose
Published in Diabetes (New York, N.Y.) (01-06-1999)“…Impaired beta-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose. S Marshak , G Leibowitz , F Bertuzzi , C Socci ,…”
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Genetic variations in GPSM3 associated with protection from rheumatoid arthritis affect its transcript abundance
Published in Genes and immunity (01-03-2016)“…G protein signaling modulator 3 (GPSM3) is a regulator of G protein-coupled receptor signaling, with expression restricted to leukocytes and lymphoid organs…”
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Efficacy of everolimus plus octreotide LAR in patients with advanced neuroendocrine tumor and carcinoid syndrome: final overall survival from the randomized, placebo-controlled phase 3 RADIANT-2 study
Published in Annals of oncology (01-07-2017)“…In the phase 3 RADIANT-2 study, everolimus plus octreotide long-acting repeatable (LAR) showed improvement of 5.1months in median progression-free survival…”
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Site-Resolved Determination of Peptide Torsion Angle φ from the Relative Orientations of Backbone N−H and C−H Bonds by Solid-State NMR
Published in The journal of physical chemistry. B (24-07-1997)“…We describe a method for determining the torsion angle φ in peptides. The technique is based on the measurement of the relative orientation of the N−HN and…”
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Obesity and surgical complications of pancreaticoduodenectomy: An observation study utilizing ACS NSQIP
Published in The American journal of surgery (01-07-2020)“…An estimated 38% of US adults are obese. Obesity is associated with socioeconomic disparities and increased rates of comorbidities, and is a known risk factor…”
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The Role of Symmetry in Fundamental Physics
Published in Proceedings of the National Academy of Sciences - PNAS (10-12-1996)“…The role of symmetry in fundamental physics is reviewed…”
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Developmental decisions in Dictyostelium discoideum
Published in Microbiological reviews (01-09-1994)“…A few hours after the onset of starvation, amoebae of Dictyostelium discoideum start to form multicellular aggregates by chemotaxis to centers that emit…”
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Discovery of a functionally selective ghrelin receptor (GHSR 1a ) ligand for modulating brain dopamine
Published in Proceedings of the National Academy of Sciences - PNAS (08-03-2022)“…SignificanceThe modulation of growth hormone secretagogue receptor-1a (GHSR ) signaling is a promising strategy for treating brain conditions of metabolism,…”
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Function of a genetically modified human liver cell line that stores, processes and secretes insulin
Published in Gene therapy (01-03-2003)“…An alternative approach to the treatment of type I diabetes is the use of genetically altered neoplastic liver cells to synthesize, store and secrete insulin…”
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Proinsulin processing in the diabetic Goto-Kakizaki rat
Published in Journal of endocrinology (01-12-2002)“…The biosynthesis and processing of proinsulin was investigated in the diabetic Goto-Kakizaki (GK) rat. Immunofluorescence microscopy comparing GK and Wistar…”
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Novel and evolving therapies in the treatment of malignant phaeochromocytoma: experience with the mTOR inhibitor everolimus (RAD001)
Published in Hormone and metabolic research (01-09-2009)“…Phaeochromocytoma and paraganglioma are rare neuroendocrine tumours (NETS). They may be benign or malignant but the pathological distinction is mainly made…”
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The role of hepatic trans-arterial chemoembolization in metastatic medullary thyroid carcinoma: a specialist center experience and review of the literature
Published in European journal of endocrinology (01-04-2017)“…Background Liver metastases are relatively common in patients with metastatic medullary thyroid carcinoma (MTC), carrying a negative impact on disease…”
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Hepatic intra-arterial therapies in metastatic neuroendocrine tumors: lessons from clinical practice
Published in Endocrine (01-06-2018)“…Background Liver metastases are common in patients with neuroendocrine tumors (NETs), having a negative impact on disease prognosis. The options for selective…”
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Everolimus therapy for progressive adrenocortical cancer
Published in Endocrine (01-08-2013)“…Patients with advanced adrenocortical carcinoma (ACC) have limited treatment options after failure of chemotherapy. Tumor IGF2 expression has been shown to be…”
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Morphological study of the anatomical variations of anterior belly of digastric muscle in Brazilian cadavers
Published in Folia morphologica (01-01-2023)“…BACKGROUND: Cases of variations in anterior belly of the digastric muscle must becarefully identified to avoid misinterpretations and assist in the correct…”
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