Search Results - "Groshong, Steve"

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium by Seibold, Max A, Smith, Russell W, Urbanek, Cydney, Groshong, Steve D, Cosgrove, Gregory P, Brown, Kevin K, Schwarz, Marvin I, Schwartz, David A, Reynolds, Susan D

“…We previously identified a MUC5B gene promoter-variant that is a risk allele for sporadic and familial Idiopathic Pulmonary Fibrosis/Usual Interstitial…”
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An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals by Matute-Bello, Gustavo, Downey, Gregory, Moore, Bethany B, Groshong, Steve D, Matthay, Michael A, Slutsky, Arthur S, Kuebler, Wolfgang M

“…Acute lung injury (ALI) is well defined in humans, but there is no agreement as to the main features of acute lung injury in animal models. A Committee was…”
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CT Scan Findings of Probable Usual Interstitial Pneumonitis Have a High Predictive Value for Histologic Usual Interstitial Pneumonitis by Chung, Jonathan H., MD, Chawla, Ashish, MD, Peljto, Anna L., PhD, Cool, Carlyne D., MD, Groshong, Steve D., MD, Talbert, Janet L., MS, McKean, David F., BS, Brown, Kevin K., MD, FCCP, Fingerlin, Tasha E., PhD, Schwarz, Marvin I., MD, FCCP, Schwartz, David A., MD, Lynch, David A., MBBS

“…The current usual interstitial pneumonitis (UIP)/idiopathic pulmonary fibrosis CT scan classification system excludes probable UIP as a diagnostic category. We…”
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Modern Age Pathology of Pulmonary Arterial Hypertension by STACHER, Elvira, GRAHAM, Brian B, TUDER, Rubin M, HUNT, James M, GANDJEVA, Aneta, GROSHONG, Steve D, MCLAUGHLIN, Vallerie V, JESSUP, Marsha, GRIZZLE, William E, ALDRED, Michaela A, COOL, Carlyne D

“…The impact of modern treatments of pulmonary arterial hypertension (PAH) on pulmonary vascular pathology remains unknown. To assess the spectrum of pulmonary…”
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Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis by Yang, Ivana V, Coldren, Christopher D, Leach, Sonia M, Seibold, Max A, Murphy, Elissa, Lin, Jia, Rosen, Rachel, Neidermyer, Amanda J, McKean, David F, Groshong, Steve D, Cool, Carlyne, Cosgrove, Gregory P, Lynch, David A, Brown, Kevin K, Schwarz, Marvin I, Fingerlin, Tasha E, Schwartz, David A

“…Idiopathic pulmonary fibrosis (IPF) is an untreatable lung disease with a median survival of only 3-5 years that is diagnosed using a combination of clinical,…”
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A Common MUC5B Promoter Polymorphism and Pulmonary Fibrosis by Seibold, Max A, Wise, Anastasia L, Speer, Marcy C, Steele, Mark P, Brown, Kevin K, Loyd, James E, Fingerlin, Tasha E, Zhang, Weiming, Gudmundsson, Gunnar, Groshong, Steve D, Evans, Christopher M, Garantziotis, Stavros, Adler, Kenneth B, Dickey, Burton F, du Bois, Roland M, Yang, Ivana V, Herron, Aretha, Kervitsky, Dolly, Talbert, Janet L, Markin, Cheryl, Park, Joungjoa, Crews, Anne L, Slifer, Susan H, Auerbach, Scott, Roy, Michelle G, Lin, Jia, Hennessy, Corinne E, Schwarz, Marvin I, Schwartz, David A

“…The pathobiology of idiopathic pulmonary fibrosis remains largely unknown. In this study, a variety of genetic techniques were used to implicate variants in…”
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Utility of a Molecular Classifier as a Complement to High-Resolution Computed Tomography to Identify Usual Interstitial Pneumonia by Richeldi, Luca, Scholand, Mary Beth, Lynch, David A, Colby, Thomas V, Myers, Jeffrey L, Groshong, Steve D, Chung, Jonathan H, Benzaquen, Sadia, Nathan, Steven D, Davis, J Russell, Schmidt, Shelley L, Hagmeyer, Lars, Sonetti, David, Hetzel, Jurgen, Criner, Gerard J, Case, Amy H, Ramaswamy, Murali, Calero, Karel, Gauhar, Umair A, Patel, Nina M, Lancaster, Lisa, Choi, Yoonha, Pankratz, Daniel G, Walsh, P Sean, Lofaro, Lori R, Huang, Jing, Bhorade, Sangeeta M, Kennedy, Giulia C, Martinez, Fernando J, Raghu, Ganesh

“…Usual interstitial pneumonia (UIP) is the defining morphology of idiopathic pulmonary fibrosis (IPF). Guidelines for IPF diagnosis conditionally recommend…”
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Lymphangioleiomyomatosis and Other Cystic Lung Diseases by Koslow, Matthew, Lynch, David A., Cool, Carlyne D., Groshong, Steve D., Downey, Gregory P.

“…Cysts and cavities in the lung are commonly encountered on chest imaging. It is necessary to distinguish thin-walled lung cysts (≤2 mm) from cavities and…”
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Usual Interstitial Pneumonia Can Be Detected in Transbronchial Biopsies Using Machine Learning by Pankratz, Daniel G, Choi, Yoonha, Imtiaz, Urooj, Fedorowicz, Grażyna M, Anderson, Jessica D, Colby, Thomas V, Myers, Jeffrey L, Lynch, David A, Brown, Kevin K, Flaherty, Kevin R, Steele, Mark P, Groshong, Steve D, Raghu, Ganesh, Barth, Neil M, Walsh, P Sean, Huang, Jing, Kennedy, Giulia C, Martinez, Fernando J

“…Usual interstitial pneumonia (UIP) is the histopathologic hallmark of idiopathic pulmonary fibrosis. Although UIP can be detected by high-resolution computed…”
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Photodynamic therapy via navigational bronchoscopy for peripheral lung cancer in dogs by Musani, Ali I., Veir, Julia K., Huang, Zheng, Lei, Tim, Groshong, Steve, Worley, Deanna

“…Objective In the setting of lung cancer, photodynamic therapy (PDT) is typically used to treat centrally located endobronchial tumors. The development of…”
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Serum amyloid A regulates granulomatous inflammation in sarcoidosis through Toll-like receptor-2 by Chen, Edward S, Song, Zhimin, Willett, Matthew H, Heine, Shannon, Yung, Rex C, Liu, Mark C, Groshong, Steve D, Zhang, Ying, Tuder, Rubin M, Moller, David R

“…The critical innate immune mechanisms that regulate granulomatous inflammation in sarcoidosis are unknown. Because the granuloma-inducing component of…”
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Lung disease with anti-CCP antibodies but not rheumatoid arthritis or connective tissue disease by Fischer, Aryeh, Solomon, Joshua J, du Bois, Roland M, Deane, Kevin D, Olson, Amy L, Fernandez-Perez, Evans R, Huie, Tristan J, Stevens, Allen D, Gill, Mary B, Rabinovitch, Avi M, Lynch, David A, Burns, David A, Pineiro, Isabel S, Groshong, Steve D, Duarte Achcar, Rosane D, Brown, Kevin K, Martin, Richard J, Swigris, Jeffrey J

“…Summary Objective We sought to characterize a novel cohort of patients with lung disease, anti-cyclic citrullinated peptide (CCP) antibody positivity, without…”
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Protein Tyrosine Phosphatase-N13 Promotes Myofibroblast Resistance to Apoptosis in Idiopathic Pulmonary Fibrosis by Bamberg, Alison, Redente, Elizabeth F, Groshong, Steve D, Tuder, Rubin M, Cool, Carlyne D, Keith, Rebecca C, Edelman, Benjamin L, Black, Bart P, Cosgrove, Gregory P, Wynes, Murry W, Curran-Everett, Douglas, De Langhe, Stijn, Ortiz, Luis A, Thorburn, Andrew, Riches, David W H

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, fibrotic interstitial lung disease characterized by (myo)fibroblast accumulation and collagen deposition…”
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Refractory Asthma: Importance of Bronchoscopy to Identify Phenotypes and Direct Therapy by GOOD, James T, KOLAKOWSKI, Christena A, GROSHONG, Steve D, MURPHY, James R, MARTIN, Richard J

“…The pathophysiology of refractory asthma is not well understood; thus, treatment modalities are not targeted to specific phenotypes but rather to a broad-based…”
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Fibroblast Foci Are Not Discrete Sites of Lung Injury or Repair: The Fibroblast Reticulum by Cool, Carlyne D, Groshong, Steve D, Rai, Pradeep R, Henson, Peter M, Stewart, J. Scott, Brown, Kevin K

“…Usual interstitial pneumonia (UIP), the pathologic correlate of idiopathic pulmonary fibrosis, contains characteristic discrete areas of fibroblasts,…”
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Protein tyrosine phosphatase-α amplifies transforming growth factor-β-dependent profibrotic signaling in lung fibroblasts by Aschner, Yael, Nelson, Meghan, Brenner, Matthew, Roybal, Helen, Beke, Keriann, Meador, Carly, Foster, Daniel, Correll, Kelly A, Reynolds, Paul R, Anderson, Kelsey, Redente, Elizabeth F, Matsuda, Jennifer, Riches, David W H, Groshong, Steve D, Pozzi, Ambra, Sap, Jan, Wang, Qin, Rajshankar, Dhaarmini, McCulloch, Christopher A G, Zemans, Rachel L, Downey, Gregory P

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, often fatal, fibrosing lung disease for which treatment remains suboptimal. Fibrogenic cytokines,…”
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Molecular phenotypes distinguish patients with relatively stable from progressive idiopathic pulmonary fibrosis (IPF) by Boon, Kathy, Bailey, Nathaniel W, Yang, Jun, Steel, Mark P, Groshong, Steve, Kervitsky, Dolly, Brown, Kevin K, Schwarz, Marvin I, Schwartz, David A

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic interstitial lung disease that is unresponsive to current therapy and often leads to death…”
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The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis by Okamoto, Tsukasa, Mathai, Susan K, Hennessy, Corinne E, Hancock, Laura A, Walts, Avram D, Stefanski, Adrianne L, Brown, Kevin K, Lynch, David A, Cosgrove, Gregory P, Groshong, Steve D, Cool, Carlyne D, Schwarz, Marvin I, Banda, Nirmal K, Thurman, Joshua M, Yang, Ivana V, Holers, V Michael, Schwartz, David A

“…The common gain-of-function MUC5B promoter variant ( rs35705950 ) is the strongest risk factor for the development of idiopathic pulmonary fibrosis (IPF)…”
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Pulmonary Manifestations of Common Variable Immunodeficiency by Bang, Tami J, Richards, John Caleb, Olson, Amy L, Groshong, Steve D, Gelfand, Erwin W, Lynch, David A

“…Common variable immunodeficiency (CVID) is associated with significant chronic lung disease. The purpose of this paper was to describe the clinical,…”
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Gastrin-releasing peptide receptor expression in lung cancer by Mattei, Jane, Achcar, Rosane D, Cano, Carlos H, Macedo, Bruno R, Meurer, Luise, Batlle, Brenda S, Groshong, Steve D, Kulczynski, Jane M, Roesler, Rafael, Dal Lago, Lissandra, Brunetto, Andre T, Schwartsmann, Gilberto

“…Gastrin-releasing peptide receptors (GRPRs) activate mitogen-activated protein kinase signaling pathway primarily through epidermal growth factor receptor…”
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