Search Results - "Grosbois, Bernard"
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Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99–06): a randomised trial
Published in The Lancet (British edition) (06-10-2007)“…Summary Background In multiple myeloma, combination chemotherapy with melphalan plus prednisone is still regarded as the standard of care in elderly patients…”
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Achievement of VGPR to induction therapy is an important prognostic factor for longer PFS in the IFM 2005-01 trial
Published in Blood (17-03-2011)“…In the 2005-01 trial, we have demonstrated that bortezomib-dexamethasone as induction therapy before autologous stem cell transplantation was superior to…”
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The French Gaucher's disease registry: clinical characteristics, complications and treatment of 562 patients
Published in Orphanet journal of rare diseases (09-10-2012)“…Clinical features, complications and treatments of Gaucher's disease (GD), a rare autosomal-recessive disorder due to a confirmed lysosomal enzyme…”
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Gastrointestinal manifestations in mastocytosis: A study of 83 patients
Published in Journal of allergy and clinical immunology (01-10-2013)“…Background Mastocytosis is a heterogeneous disease characterized by mast cell accumulation in 1 or more organs. Gastrointestinal manifestations of systemic…”
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Altered innate function of plasmacytoid dendritic cells restored by enzyme replacement therapy in Gaucher disease
Published in Blood cells, molecules, & diseases (01-04-2013)“…Gaucher disease (GD) is caused by an autosomal-recessive deficiency of β-glucocerebrosidase leading to an accumulation of glucosylceramide in…”
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Autoimmune and inflammatory manifestations occur frequently in patients with primary immunodeficiencies
Published in Journal of allergy and clinical immunology (01-11-2017)“…Primary immunodeficiencies (PIDs) are inherited diseases associated with a considerable increase in susceptibility to infections. It is known that PIDs can…”
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Clinical picture and treatment of 2212 patients with common variable immunodeficiency
Published in Journal of allergy and clinical immunology (01-07-2014)“…Background Common variable immunodeficiency (CVID) is an antibody deficiency with an equal sex distribution and a high variability in clinical presentation…”
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Long-term efficacy and safety of cladribine (2-CdA) in adult patients with mastocytosis
Published in Blood (20-08-2015)“…Mastocytosis (M) is a clonal myeloid-disabling disorder for which no curative therapy is currently available. Cladribine (2-chlorodeoxyadenosine [2-CdA]) is a…”
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Anti-HMGCR Autoantibodies in European Patients With Autoimmune Necrotizing Myopathies: Inconstant Exposure to Statin
Published in Medicine (Baltimore) (01-05-2014)“…Necrotizing autoimmune myopathy (NAM) is a group of acquired myopathies characterized by prominent myofiber necrosis with little or no muscle inflammation…”
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Mature plasma cells as indicator of better prognosis in multiple myeloma. New methodology for the assessment of plasma cell morphology
Published in Leukemia research (01-12-1999)“…The relationship between plasmablastic cells and outcome in multiple myeloma (MM) has been established for nearly 15 years. But the assessment of these cells…”
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Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome
Published in Blood (15-04-2007)“…Acquired genomic aberrations have been shown to significantly impact survival in several hematologic malignancies. We analyzed the prognostic value of the most…”
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Dermatomyositis With or Without Anti-Melanoma Differentiation-Associated Gene 5 Antibodies: Common Interferon Signature but Distinct NOS2 Expression
Published in The American journal of pathology (01-03-2016)“…The anti-melanoma differentiation-associated gene 5 (MDA5) autoantibody is specifically associated with dermatomyositis (DM). Nevertheless,…”
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Prognostic value of high-sensitivity measurable residual disease assessment after front-line chemoimmunotherapy in chronic lymphocytic leukemia
Published in Leukemia (01-06-2021)“…Measurable residual disease (MRD) status is widely adopted in clinical trials in patients with chronic lymphocytic leukemia (CLL). Findings from FILO group…”
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Mast cells' involvement in inflammation pathways linked to depression: evidence in mastocytosis
Published in Molecular psychiatry (01-11-2016)“…Converging sources of evidence point to a role for inflammation in the development of depression, fatigue and cognitive dysfunction. More precisely, the…”
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An appraisal of the frequency and severity of noninfectious manifestations in primary immunodeficiencies: A study of a national retrospective cohort of 1375 patients over 10 years
Published in Journal of allergy and clinical immunology (01-06-2022)“…Noninfectious manifestations—allergy, autoimmunity/inflammation, lymphoproliferation, and malignancies—are known to exist in many primary immunodeficiency…”
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Single versus Double Autologous Stem-Cell Transplantation for Multiple Myeloma
Published in The New England journal of medicine (25-12-2003)“…This investigation of the treatment of multiple myeloma compared one cycle of high-dose chemotherapy plus a single autologous stem-cell transplantation with…”
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Long-term effectiveness and safety of interleukin-1 receptor antagonist (anakinra) in Schnitzler's syndrome: A french multicenter study
Published in Autoimmunity reviews (01-10-2014)“…Abstract The aim of this study is to assess the long-term effectiveness and safety of IL1Ra in Schnitzler syndrome (SchS). Between 2010 and 2012, we performed…”
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Genetic diagnosis of primary immunodeficiencies: A survey of the French national registry
Published in Journal of allergy and clinical immunology (01-04-2019)“…[...]the (genetic) diagnostic delay was long for many patients (see below). [...]we looked at whether the patients' region of residence within France (which…”
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Long‐term outcome of monoclonal (type 1) cryoglobulinemia
Published in American journal of hematology (01-02-2014)“…The aim of this study is to investigate long‐term outcome of symptomatic type 1 cryoglobulinemia (CG) and its determinants. Retrospective cohort study was…”
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