Search Results - "Groothoff, Jaap"

Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1 by Garrelfs, Sander F, Frishberg, Yaacov, Hulton, Sally A, Koren, Michael J, O’Riordan, William D, Cochat, Pierre, Deschênes, Georges, Shasha-Lavsky, Hadas, Saland, Jeffrey M, van’t Hoff, William G, Fuster, Daniel G, Magen, Daniella, Moochhala, Shabbir H, Schalk, Gesa, Simkova, Eva, Groothoff, Jaap W, Sas, David J, Meliambro, Kristin A, Lu, Jiandong, Sweetser, Marianne T, Garg, Pushkal P, Vaishnaw, Akshay K, Gansner, John M, McGregor, Tracy L, Lieske, John C

“…Primary hyperoxaluria type 1 is caused by hepatic overproduction of oxalate, leading to kidney stones, nephrocalcinosis, kidney failure, and systemic oxalosis…”
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20-Year Follow-up of Statins in Children with Familial Hypercholesterolemia by Luirink, Ilse K, Wiegman, Albert, Kusters, D. Meeike, Hof, Michel H, Groothoff, Jaap W, de Groot, Eric, Kastelein, John J.P, Hutten, Barbara A

“…Familial hypercholesterolemia is marked by very elevated low-density lipoprotein cholesterol levels and premature cardiovascular disease. This 20-year…”
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Clinical practice recommendations for primary hyperoxaluria: an expert consensus statement from ERKNet and OxalEurope by Groothoff, Jaap W., Metry, Ella, Deesker, Lisa, Garrelfs, Sander, Acquaviva, Cecile, Almardini, Reham, Beck, Bodo B., Boyer, Olivia, Cerkauskiene, Rimante, Ferraro, Pietro Manuel, Groen, Luitzen A., Gupta, Asheeta, Knebelmann, Bertrand, Mandrile, Giorgia, Moochhala, Shabbir S., Prytula, Agnieszka, Putnik, Jovana, Rumsby, Gill, Soliman, Neveen A., Somani, Bhaskar, Bacchetta, Justine

“…Primary hyperoxaluria (PH) is an inherited disorder that results from the overproduction of endogenous oxalate, leading to recurrent kidney stones,…”
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Safety, pharmacodynamics, and exposure-response modeling results from a first-in-human phase 1 study of nedosiran (PHYOX1) in primary hyperoxaluria by Hoppe, Bernd, Koch, Annelize, Cochat, Pierre, Garrelfs, Sander F, Baum, Michelle A, Groothoff, Jaap W, Lipkin, Graham, Coenen, Martin, Schalk, Gesa, Amrite, Aniruddha, McDougall, David, Barrios, Kelly, Langman, Craig B

“…Primary hyperoxaluria (PH) is a family of ultra-rare autosomal recessive inherited disorders of hepatic glyoxylate metabolism characterized by oxalate…”
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ESPN2021: Interactive hybrid—the future of medical congresses? by Bökenkamp, Arend, Schreuder, Michiel, Groothoff, Jaap

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Health-related quality of life in patients with pediatric onset of end-stage renal disease: state of the art and recommendations for clinical practice by Tjaden, Lidwien A., Grootenhuis, Martha A., Noordzij, Marlies, Groothoff, Jaap W.

“…Health-related quality of life (HRQoL) is increasingly recognized as a key outcome in both clinical and research settings in the pediatric population with…”
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Long-term consequences of renal insufficiency in children: lessons learned from the Dutch LERIC study by Groothoff, Jaap W, Offringa, Martin, Grootenhuis, Martha, Jager, Kitty J

“…Few data exist on the prospects in adulthood for children on chronic renal replacement therapy (RRT). This article summarizes the results of a comprehensive…”
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Racial Disparities in Access to and Outcomes of Kidney Transplantation in Children, Adolescents, and Young Adults: Results From the ESPN/ERA-EDTA (European Society of Pediatric Nephrology/European Renal Association−European Dialysis and Transplant Association) Registry by Tjaden, Lidwien A., MD, Noordzij, Marlies, PhD, van Stralen, Karlijn J., PhD, Kuehni, Claudia E., MD, Raes, Ann, MD, PhD, Cornelissen, Elisabeth A.M., MD, PhD, O’Brien, Catherine, MD, PhD, Papachristou, Fotios, MD, PhD, Schaefer, Franz, MD, PhD, Groothoff, Jaap W., MD, PhD, Jager, Kitty J., MD, PhD

“…Background Racial disparities in kidney transplantation in children have been found in the United States, but have not been studied before in Europe. Study…”
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A report from the European Hyperoxaluria Consortium (OxalEurope) Registry on a large cohort of patients with primary hyperoxaluria type 3 by Martin-Higueras, Cristina, Garrelfs, Sander F, Groothoff, Jaap W, Jacob, Dorrit E, Moochhala, Shabbir H, Bacchetta, Justine, Acquaviva, Cecile, Zaniew, Marcin, Sikora, Przymyslaw, Beck, Bodo B, Hoppe, Bernd

“…Outcome data in primary hyperoxaluria type 3 (PH3), described as a less severe form of the PH's with a low risk of chronic kidney disease, are scarce. To…”
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Lumasiran for Advanced Primary Hyperoxaluria Type 1: Phase 3 ILLUMINATE-C Trial by Michael, Mini, Groothoff, Jaap W., Shasha-Lavsky, Hadas, Lieske, John C., Frishberg, Yaacov, Simkova, Eva, Sellier-Leclerc, Anne-Laure, Devresse, Arnaud, Guebre-Egziabher, Fitsum, Bakkaloglu, Sevcan A., Mourani, Chebl, Saqan, Rola, Singer, Richard, Willey, Richard, Habtemariam, Bahru, Gansner, John M., Bhan, Ishir, McGregor, Tracy, Magen, Daniella

“…Lumasiran reduces urinary and plasma oxalate (POx) in patients with primary hyperoxaluria type 1 (PH1) and relatively preserved kidney function. ILLUMINATE-C…”
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Phase 1/2 Study of Lumasiran for Treatment of Primary Hyperoxaluria Type 1: A Placebo-Controlled Randomized Clinical Trial by Frishberg, Yaacov, Deschênes, Georges, Groothoff, Jaap W, Hulton, Sally-Anne, Magen, Daniella, Harambat, Jérôme, Van't Hoff, William G, Lorch, Ulrike, Milliner, Dawn S, Lieske, John C, Haslett, Patrick, Garg, Pushkal P, Vaishnaw, Akshay K, Talamudupula, Sandeep, Lu, Jiandong, Habtemariam, Bahru A, Erbe, David V, McGregor, Tracy L, Cochat, Pierre

“…In the rare disease primary hyperoxaluria type 1, overproduction of oxalate by the liver causes kidney stones, nephrocalcinosis, kidney failure, and systemic…”
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Practice of lipoprotein apheresis and short-term efficacy in children with homozygous familial hypercholesterolemia: Data from an international registry by Luirink, Ilse K., Hutten, Barbara A., Greber-Platzer, Susanne, Kolovou, Genovefa D., Dann, Eldad J., de Ferranti, Sarah D., Taylan, Christina, Bruckert, Eric, Saheb, Samir, Oh, Jun, Driemeyer, Joenna, Farnier, Michel, Pape, Lars, Schmitt, Claus P., Novoa, Francisco J., Maeser, Martin, Masana, Luis, Shahrani, Awad, Wiegman, Albert, Groothoff, Jaap W.

“…Homozygous familial hypercholesterolemia (hoFH) may cause life-threatening atherosclerotic cardiovascular disease in childhood. Lipoprotein apheresis (LA) is…”
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Marked plaque regression in homozygous familial hypercholesterolemia by Reeskamp, Laurens F., Nurmohamed, Nick S., Bom, Michiel J., Planken, R. Nils, Driessen, Roel S., van Diemen, Pepijn A., Luirink, Ilse K., Groothoff, Jaap W., Kuipers, Irene M., Knaapen, Paul, Stroes, Erik S.G., Wiegman, Albert, Hovingh, G. Kees

“…Both plasma low-density lipoprotein (LDL) cholesterol levels and risk for premature cardiovascular disease are extremely elevated in patients with homozygous…”
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Mortality risk disparities in children receiving chronic renal replacement therapy for the treatment of end-stage renal disease across Europe: an ESPN-ERA/EDTA registry analysis by Chesnaye, Nicholas C, MSc, Schaefer, Franz, Prof, Bonthuis, Marjolein, PhD, Holman, Rebecca, PhD, Baiko, Sergey, PhD, Baskın, Esra, MD, Bjerre, Anna, PhD, Cloarec, Sylvie, MD, Cornelissen, Elisabeth A M, PhD, Espinosa, Laura, MD, Heaf, James, DMSc, Stone, Rosário, MD, Shtiza, Diamant, PhD, Zagozdzon, Ilona, PhD, Harambat, Jérôme, Prof, Jager, Kitty J, Prof, Groothoff, Jaap W, MD, van Stralen, Karlijn J, PhD

“…Summary Background We explored the variation in country mortality rates in the paediatric population receiving renal replacement therapy across Europe, and…”
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Growth Patterns After Kidney Transplantation in European Children Over the Past 25 Years: An ESPN/ERA-EDTA Registry Study by Bonthuis, Marjolein, Groothoff, Jaap W., Ariceta, Gema, Baiko, Sergey, Battelino, Nina, Bjerre, Anna, Cransberg, Karlien, Kolvek, Gabriel, Maxwell, Heather, Miteva, Polina, Molchanova, Maria S., Neuhaus, Thomas J., Pape, Lars, Reusz, Gyorgy, Rousset-Rouviere, Caroline, Sandes, Ana Rita, Topaloglu, Rezan, Van Dyck, Maria, Ylinen, Elisa, Zagozdzon, Ilona, Jager, Kitty J., Harambat, Jérôme

“…BACKGROUND.Improved management of growth impairment might have resulted in less growth retardation after pediatric kidney transplantation (KT) over time. We…”
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Mortality risk in European children with end-stage renal disease on dialysis by Chesnaye, Nicholas C, Schaefer, Franz, Groothoff, Jaap W, Bonthuis, Marjolein, Reusz, György, Heaf, James G, Lewis, Malcolm, Maurer, Elisabeth, Paripović, Dušan, Zagozdzon, Ilona, van Stralen, Karlijn J, Jager, Kitty J

“…We aimed to describe survival in European pediatric dialysis patients and compare the differential mortality risk between patients starting on hemodialysis…”
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Efficacy and safety of lipoprotein apheresis in children with homozygous familial hypercholesterolemia: A systematic review by Luirink, Ilse K., Determeijer, Jim, Hutten, Barbara A., Wiegman, Albert, Bruckert, Eric, Schmitt, Claus P., Groothoff, Jaap W.

“…Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder that may cause life-threatening cardiovascular disease (CVD) at childhood. Marginal…”
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Children on dialysis as well as renal transplanted children report severely impaired health-related quality of life by Splinter, Anouck, Tjaden, Lidwien A., Haverman, Lotte, Adams, Brigitte, Collard, Laure, Cransberg, Karlien, van Dyck, Maria, Van Hoeck, Koen J., Hoppe, Bernd, Koster-Kamphuis, Linda, Lilien, Marc R., Raes, Ann, Taylan, Christina, Grootenhuis, Martha A., Groothoff, Jaap W.

“…Objectives To assess health-related quality of life (HRQoL) across three renal replacement therapy modalities (preemptive transplant, non-preemptive…”
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Glycolate oxidase inhibition by lumasiran varies between patients with primary hyperoxaluria type 1 by Garrelfs, Sander F, Metry, Elisabeth L, van Harskamp, Dewi, Vaz, Frederic M, van den Akker, Chris H P, Schierbeek, Henk, Groothoff, Jaap W, Oosterveld, Michiel J S

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The European Rare Kidney Disease Registry (ERKReg): objectives, design and initial results by Bassanese, Giulia, Wlodkowski, Tanja, Servais, Aude, Heidet, Laurence, Roccatello, Dario, Emma, Francesco, Levtchenko, Elena, Ariceta, Gema, Bacchetta, Justine, Capasso, Giovambattista, Jankauskiene, Augustina, Miglinas, Marius, Ferraro, Pietro Manuel, Montini, Giovanni, Oh, Jun, Decramer, Stephane, Levart, Tanja Kersnik, Wetzels, Jack, Cornelissen, Elisabeth, Devuyst, Olivier, Zurowska, Aleksandra, Pape, Lars, Buescher, Anja, Haffner, Dieter, Marcun Varda, Natasa, Ghiggeri, Gian Marco, Remuzzi, Giuseppe, Konrad, Martin, Longo, Germana, Bockenhauer, Detlef, Awan, Atif, Andersone, Ilze, Groothoff, Jaap W, Schaefer, Franz

“…Abstract Background The European Rare Kidney Disease Reference Network (ERKNet) recently established ERKReg, a Web-based registry for all patients with rare…”
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