Search Results - "Grootendorst, Jeannette"
-
1
Severe learning deficits in apolipoprotein E-knockout mice in a water maze task
Published in Brain research (28-03-1997)“…Recent studies on apolipoprotein E (apoE) have stressed the importance of this protein in neuronal viability, especially in the hippocampal area. In the…”
Get full text
Journal Article -
2
Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks
Published in Behavioural brain research (21-11-2008)“…Apolipoprotein (apo) E4, one of three human apoE (h-apoE) isoforms, has been identified as a major genetic risk factor for Alzheimer's disease and for…”
Get full text
Journal Article -
3
Human apoE targeted replacement mouse lines: h-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior
Published in Behavioural brain research (15-04-2005)“…Apolipoprotein E4 (apoE4), one of the three most common human apoE (h-apoE) isoforms, is a major genetic risk factor for Alzheimer's disease and for cognitive…”
Get full text
Journal Article -
4
Quantification of swim patterns in the Morris water maze
Published in Behavior research methods, instruments, & computers (01-02-2000)“…Spatial learning and memory in rodents is most often assessed in the Morris water maze. Neurobiologists have to distinguish behavioral patterns to unravel…”
Get full text
Journal Article -
5
Increased corticosterone secretion and early-onset of cognitive decline in female apolipoprotein E-knockout mice
Published in Behavioural brain research (05-01-2004)“…In the present study, the interaction of age and apolipoprotein E (apoE)-genetic background on cognitive abilities was investigated in young (5–6 months) and…”
Get full text
Journal Article -
6
Gene x environment interaction and cognitive performance: Animal studies on the role of corticosterone
Published in Neurobiology of learning and memory (01-11-2002)“…A fundamental question in the neurobiology of cognition is how stress and glucocorticoids modify learning and memory processes. Why some individuals develop…”
Get full text
Conference Proceeding Journal Article -
7
Presence of apolipoprotein E immunoreactivity in degenerating neurones of mice is dependent on the severity of kainic acid-induced lesion
Published in Brain research (23-06-2000)“…Apolipoprotein E (apoE) is a major apolipoprotein in the central nervous system (CNS) that may play a role in various CNS disorders. ApoE is primarily…”
Get full text
Journal Article -
8
Gene × Environment Interaction and Cognitive Performance: Animal Studies on the Role of Corticosterone
Published in Neurobiology of learning and memory (01-11-2002)“…A fundamental question in the neurobiology of cognition is how stress and glucocorticoids modify learning and memory processes. Why some individuals develop…”
Get full text
Journal Article