Search Results - "Groot, A J"

Diagnostic and prognostic prediction models by Hendriksen, J. M. T., Geersing, G. J., Moons, K. G. M., Groot, J. A. H.

“…Summary Risk prediction models can be used to estimate the probability of either having (diagnostic model) or developing a particular disease or outcome…”
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The genomic landscape of compensatory evolution by Szamecz, Béla, Boross, Gábor, Kalapis, Dorottya, Kovács, Károly, Fekete, Gergely, Farkas, Zoltán, Lázár, Viktória, Hrtyan, Mónika, Kemmeren, Patrick, Groot Koerkamp, Marian J A, Rutkai, Edit, Holstege, Frank C P, Papp, Balázs, Pál, Csaba

“…Adaptive evolution is generally assumed to progress through the accumulation of beneficial mutations. However, as deleterious mutations are common in natural…”
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EBV MicroRNA BART16 Suppresses Type I IFN Signaling by Hooykaas, Marjolein J G, van Gent, Michiel, Soppe, Jasper A, Kruse, Elisabeth, Boer, Ingrid G J, van Leenen, Dik, Groot Koerkamp, Marian J A, Holstege, Frank C P, Ressing, Maaike E, Wiertz, Emmanuel J H J, Lebbink, Robert Jan

“…Type I IFNs play critical roles in orchestrating the antiviral defense by inducing direct antiviral activities and shaping the adaptive immune response…”
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Antibacterial Behavior of Additively Manufactured Porous Titanium with Nanotubular Surfaces Releasing Silver Ions by Amin Yavari, S, Loozen, L, Paganelli, F. L, Bakhshandeh, S, Lietaert, K, Groot, J. A, Fluit, A. C, Boel, C. H. E, Alblas, J, Vogely, H. C, Weinans, H, Zadpoor, A. A

“…Additive manufacturing (3D printing) has enabled fabrication of geometrically complex and fully interconnected porous biomaterials with huge surface areas that…”
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An endometrial gene expression signature accurately predicts recurrent implantation failure after IVF by Koot, Yvonne E. M., van Hooff, Sander R., Boomsma, Carolien M., van Leenen, Dik, Groot Koerkamp, Marian J. A., Goddijn, Mariëtte, Eijkemans, Marinus J. C., Fauser, Bart C. J. M., Holstege, Frank C. P., Macklon, Nick S.

“…The primary limiting factor for effective IVF treatment is successful embryo implantation. Recurrent implantation failure (RIF) is a condition whereby couples…”
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Single-cell transcriptomics reveals immune suppression and cell states predictive of patient outcomes in rhabdomyosarcoma by DeMartino, Jeff, Meister, Michael T., Visser, Lindy L., Brok, Mariël, Groot Koerkamp, Marian J. A., Wezenaar, Amber K. L., Hiemcke-Jiwa, Laura S., de Souza, Terezinha, Merks, Johannes H. M., Rios, Anne C., Holstege, Frank C. P., Margaritis, Thanasis, Drost, Jarno

“…Paediatric rhabdomyosarcoma (RMS) is a soft tissue malignancy of mesenchymal origin that is thought to arise as a consequence of derailed myogenic…”
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Modulation of glutamine metabolism by the PI(3)K–PKB–FOXO network regulates autophagy by van der Vos, Kristan E., Eliasson, Pernilla, Proikas-Cezanne, Tassula, Vervoort, Stephin J., van Boxtel, Ruben, Putker, Marrit, van Zutphen, Iris J., Mauthe, Mario, Zellmer, Sebastian, Pals, Cornelieke, Verhagen, Liesbeth P., Groot Koerkamp, Marian J. A., Braat, A. Koen, Dansen, Tobias B., Holstege, Frank C., Gebhardt, Rolf, Burgering, Boudewijn M., Coffer, Paul J.

“…The PI(3)K–PKB–FOXO signalling network provides a major intracellular hub for the regulation of cell proliferation, survival and stress resistance. Here we…”
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Cell cycle population effects in perturbation studies by O'Duibhir, Eoghan, Lijnzaad, Philip, Benschop, Joris J, Lenstra, Tineke L, van Leenen, Dik, Groot Koerkamp, Marian JA, Margaritis, Thanasis, Brok, Mariel O, Kemmeren, Patrick, Holstege, Frank CP

“…Growth condition perturbation or gene function disruption are commonly used strategies to study cellular systems. Although it is widely appreciated that such…”
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Characterization of bovine embryos cultured under conditions appropriate for sustaining human naïve pluripotency by Brinkhof, Bas, van Tol, Helena T A, Groot Koerkamp, Marian J A, Wubbolts, Richard W, Haagsman, Henk P, Roelen, Bernard A J

“…In mammalian preimplantation development, pluripotent cells are set aside from cells that contribute to extra-embryonic tissues. Although the pluripotent cell…”
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Web-based personalised information and support for patients with a neuroendocrine tumour: randomised controlled trial by de Hosson, L D, Bouma, G, Stelwagen, J, van Essen, H, de Bock, G H, de Groot, D J A, de Vries, E G E, Walenkamp, A M E

“…Patients with a neuroendocrine tumour (NET) frequently have physical and psychosocial complaints. Aim of this study is to determine whether a web-based,…”
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Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies by Raaben, Matthijs, Groot Koerkamp, Marian J. A., Rottier, Peter J. M., De Haan, Cornelis A. M.

“…Summary Many viruses, including coronaviruses, induce host translational shutoff, while maintaining synthesis of their own gene products. In this study we…”
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Gene expression profiling of histiocytic sarcomas in a canine model: the predisposed flatcoated retriever dog by Boerkamp, Kim M, van der Kooij, Marieke, van Steenbeek, Frank G, van Wolferen, Monique E, Groot Koerkamp, Marian J A, van Leenen, Dik, Grinwis, Guy C M, Penning, Louis C, Wiemer, Erik A C, Rutteman, Gerard R

“…The determination of altered expression of genes in specific tumor types and their effect upon cellular processes may create insight in tumorigenesis and help…”
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Neoadjuvant chemotherapy followed by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal cancer: a feasibility and safety study by Leimkühler, M, Hemmer, P H J, Reyners, A K L, de Groot, D J A, van Ginkel, R J, Been, L B, de Bock, G H, van Leeuwen, B L

“…Standard treatment for colorectal peritoneal carcinomatosis typically involves cytoreductive surgery, hyperthermic intraperitoneal chemotherapy (HIPEC), and if…”
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A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions by Sameith, Katrin, Amini, Saman, Groot Koerkamp, Marian J A, van Leenen, Dik, Brok, Mariel, Brabers, Nathalie, Lijnzaad, Philip, van Hooff, Sander R, Benschop, Joris J, Lenstra, Tineke L, Apweiler, Eva, van Wageningen, Sake, Snel, Berend, Holstege, Frank C P, Kemmeren, Patrick

“…Genetic interactions, or non-additive effects between genes, play a crucial role in many cellular processes and disease. Which mechanisms underlie these…”
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Quality improvement strategies for organizational change: a multiphase observational study to increase insight into nonparticipating organizations by de Groot, Jeanny J A, Timmermans, Maite, Maessen, José M C, Winkens, Bjorn, Dirksen, Carmen D, Slangen, Brigitte F M, van der Weijden, Trudy

“…The scope of implementation research is often restricted to the analysis of organizations that participate voluntarily in implementation interventions. The…”
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Expression Profiling after Prolonged Experimental Febrile Seizures in Mice Suggests Structural Remodeling in the Hippocampus by Jongbloets, Bart C, van Gassen, Koen L I, Kan, Anne A, Olde Engberink, Anneke H O, de Wit, Marina, Wolterink-Donselaar, Inge G, Groot Koerkamp, Marian J A, van Nieuwenhuizen, Onno, Holstege, Frank C P, de Graan, Pierre N E

“…Febrile seizures are the most prevalent type of seizures among children up to 5 years of age (2-4% of Western-European children). Complex febrile seizures are…”
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The two main forms of histiocytic sarcoma in the predisposed Flatcoated retriever dog display variation in gene expression by Boerkamp, Kim M, van Steenbeek, Frank G, Penning, Louis C, Groot Koerkamp, Marian J A, van Leenen, Dik, Vos-Loohuis, Manon, Grinwis, Guy C M, Rutteman, Gerard R

“…Examination of gene functions in specific tumor types improves insight in tumorigenesis and helps design better treatments. Due to the rarity of…”
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A mRNA landscape of bovine embryos after standard and MAPK-inhibited culture conditions: a comparative analysis by Brinkhof, Bas, van Tol, Helena T A, Groot Koerkamp, Marian J A, Riemers, Frank M, IJzer, Sascha G, Mashayekhi, Kaveh, Haagsman, Henk P, Roelen, Bernard A J

“…Genes and signalling pathways involved in pluripotency have been studied extensively in mouse and human pre-implantation embryos and embryonic stem (ES) cells…”
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Magnetization dynamics in an exchange-coupled NiFe/CoFe bilayer studied by x-ray detected ferromagnetic resonance by Stenning, G B G, Shelford, L R, Cavill, S A, Hoffmann, F, Haertinger, M, Hesjedal, T, Woltersdorf, G, Bowden, G J, Gregory, S A, Back, C H, Groot, P A J de, Laan, G van der

“…Exchange-coupled hard and soft magnetic layers find extensive use in data storage applications, for which their dynamical response has great importance. With…”
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The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2α by Gort, E H, van Haaften, G, Verlaan, I, Groot, A J, Plasterk, R H A, Shvarts, A, Suijkerbuijk, K P M, van Laar, T, van der Wall, E, Raman, V, van Diest, P J, Tijsterman, M, Vooijs, M

“…Hypoxia-inducible factors (HIFs) are highly conserved transcription factors that play a crucial role in oxygen homeostasis. Intratumoral hypoxia and genetic…”
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