Search Results - "Groopman, Jerome"

Physician Burnout, Interrupted by Hartzband, Pamela, Groopman, Jerome

“…The burnout problem won’t be solved without addressing the issues of autonomy, competence, and relatedness. During the Covid-19 pandemic, a sense of altruism…”
Get full text

Medical Taylorism by Hartzband, Pamela, Groopman, Jerome

“…Under economic pressure, medicine is increasingly being subjected to the efficiency principles of “Taylorism.” But applying standardization to certain vital…”
Get full text

Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy by Shrivastava, Ashutosh, Kuzontkoski, Paula M, Groopman, Jerome E, Prasad, Anil

“…Cannabidiol (CBD), a major nonpsychoactive constituent of cannabis, is considered an antineoplastic agent on the basis of its in vitro and in vivo activity…”
Get full text

The Power of Regret by Groopman, Jerome, Hartzband, Pamela

“…Despite the centrality of regret in medicine, studies have largely failed to capture its complexity and consequences. Many proposed instruments for measuring…”
Get full text

Methamphetamine Enhances HIV-1 Replication in CD4 + T-Cells via a Novel IL-1β Auto-Regulatory Loop by Lawson, Kaycie S, Prasad, Anil, Groopman, Jerome E

“…Methamphetamine (Meth) abuse is a worldwide public health problem and contributes to HIV-1 pathobiology and poor adherence to anti-retroviral therapies…”
Get full text

Correction: Activation of the Connective Tissue Growth Factor (CTGF)-Transforming Growth Factor β 1 (TGF-β 1) Axis in Hepatitis C Virus-Expressing Hepatocytes by Nagaraja, Tirumuru, Chen, Li, Balasubramanian, Anuradha, Groopman, Jerome E, Ghoshal, Kalpana, Jacob, Samson T, Leask, Andrew, Brigstock, David R, Anand, Appakkudal R, Ganju, Ramesh K

Get full text

There Is More to Life Than Death by Hartzband, Pamela, Groopman, Jerome

“…In classic medical decision analysis, when outcomes are uncertain and risk is involved, the “best” choice is the one with the “highest expected utility.” The…”
Get full text

The New Language of Medicine by Hartzband, Pamela, Groopman, Jerome

“…In the new language of medicine, patients are “customers” or “consumers”; doctors and nurses are “providers.” The words we use to explain our roles set…”
Get full text

Methamphetamine functions as a novel CD4+ T-cell activator via the sigma-1 receptor to enhance HIV-1 infection by Prasad, Anil, Kulkarni, Rutuja, Shrivastava, Ashutosh, Jiang, Shuxian, Lawson, Kaycie, Groopman, Jerome E.

“…Methamphetamine (Meth) exacerbates HIV-1 pathobiology by increasing virus transmission and replication and accelerating clinical progression to AIDS. Meth has…”
Get full text

Cocaine Enhances DC to T-cell HIV-1 Transmission by Activating DC-SIGN/LARG/LSP1 Complex and Facilitating Infectious Synapse Formation by Prasad, Anil, Kulkarni, Rutuja, Jiang, Shuxian, Groopman, Jerome E.

“…DC-SIGN is a dendritic cell surface structure which participates in binding and transmission of HIV-1. Here, for the first time we demonstrate that cocaine…”
Get full text

Activation of the connective tissue growth factor (CTGF)-transforming growth factor β 1 (TGF-β 1) axis in hepatitis C virus-expressing hepatocytes by Nagaraja, Tirumuru, Chen, Li, Balasubramanian, Anuradha, Groopman, Jerome E, Ghoshal, Kalpana, Jacob, Samson T, Leask, Andrew, Brigstock, David R, Anand, Appakkudal R, Ganju, Ramesh K

“…The pro-fibrogenic cytokine connective tissue growth factor (CTGF) plays an important role in the development and progression of fibrosis in many organ…”
Get full text

Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis by Preet, Anju, Qamri, Zahida, Nasser, Mohd W, Prasad, Anil, Shilo, Konstantin, Zou, Xianghong, Groopman, Jerome E, Ganju, Ramesh K

“…Non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths worldwide; however, only limited therapeutic treatments are available. Hence, we…”
Get full text

Slit2N/Robo1 inhibit HIV-gp120-induced migration and podosome formation in immature dendritic cells by sequestering LSP1 and WASp by Prasad, Anil, Kuzontkoski, Paula M, Shrivastava, Ashutosh, Zhu, Weiquan, Li, Dean Y, Groopman, Jerome E

“…Cell-mediated transmission and dissemination of sexually-acquired human immunodeficiency virus 1 (HIV-1) in the host involves the migration of immature…”
Get full text

Slit2N Inhibits Transmission of HIV-1 from Dendritic Cells to T-cells by Modulating Novel Cytoskeletal Elements by Shrivastava, Ashutosh, Prasad, Anil, Kuzontkoski, Paula M., Yu, Jinlong, Groopman, Jerome E.

“…Dendritic cells are among the first cells to encounter sexually acquired human immunodeficiency virus (HIV-1), in the mucosa and they can transmit HIV-1 to CD4…”
Get full text

Slit2/Robo4 signaling modulates HIV-1 gp120-induced lymphatic hyperpermeability by Zhang, Xuefeng, Yu, Jinlong, Kuzontkoski, Paula M, Zhu, Weiquan, Li, Dean Y, Groopman, Jerome E

“…Dissemination of HIV in the host involves transit of the virus and virus-infected cells across the lymphatic endothelium. HIV may alter lymphatic endothelial…”
Get full text

Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathway by Yu, Jinlong, Zhang, Xuefeng, Kuzontkoski, Paula M, Jiang, Shuxian, Zhu, Weiquan, Li, Dean Y, Groopman, Jerome E

“…Signaling through vascular endothelial growth factor C (VEGF–C) and VEGF receptor 3 (VEGFR-3) plays a central role in lymphangiogenesis and the metastasis of…”
Get full text

Much progress, still many challenges by Groopman, Jerome E

“…The arc of laboratory and clinical research on HIV/AIDS began at ground zero in the epidemic, with no knowledge of the etiological agent or rational strategy…”
Get full text

Public Health Crisis in Gaza by Groopman, Jerome

Get full text

Impact of Cancer‐Related Fatigue on the Lives of Patients: New Findings From the Fatigue Coalition by Curt, Gregory A., Breitbart, William, Cella, David, Groopman, Jerome E., Horning, Sandra J., Itri, Loretta M., Johnson, David H., Miaskowski, Christine, Scherr, Susan L., Portenoy, Russell K., Vogelzang, Nicholas J.

“…Purpose. This survey was designed to confirm the prevalence and duration of fatigue in the cancer population and to assess its physical, mental, social, and…”
Get full text

Signal Transducer and Activator of Transcription Factor 1 Mediates Apoptosis Induced by Hepatitis C Virus and HIV Envelope Proteins in Hepatocytes by Balasubramanian, Anuradha, Ganju, Ramesh K., Groopman, Jerome E.

“…Patients coinfected with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) have progressive liver disease that frequently leads to cirrhosis and…”
Get full text