Search Results - "Groopman, J E"

Endocannabinoid‐like N‐arachidonoyl serine is a novel pro‐angiogenic mediator by Zhang, X, Maor, Y, Wang, JF, Kunos, G, Groopman, JE

“…BACKGROUND AND PURPOSE N‐arachidonoyl serine (ARA‐S) is a recently identified endocannabinoid‐like lipid with weak affinity for the fully characterized…”
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Chemotherapy-Induced Anemia in Adults: Incidence and Treatment by Groopman, Jerome E., Itri, Loretta M.

“…Anemia is a common complication of myelosuppressive chemotherapy that results in a decreased functional capacity and quality of life (QOL) for cancer patients…”
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Styryl sulfonyl compounds inhibit translation of cyclin D1 in mantle cell lymphoma cells by Prasad, A, Park, I-W, Allen, H, Zhang, X, Reddy, M V R, Boominathan, R, Reddy, E P, Groopman, J E

“…Mantle cell lymphoma (MCL) is characterized by the uncontrolled overexpression of cyclin D1. Styryl sulfonyl compounds have shown potent antitumor activity…”
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Evaluation of novel cell cycle inhibitors in mantle cell lymphoma by PARK, I.-W, REDDY, M. V. R, REDDY, E. P, GROOPMAN, J. E

“…Signature abnormalities in the cell cycle and apoptotic pathway have been identified in mantle cell lymphoma (MCL), affording the opportunity to develop…”
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Regulation of Platelet Activation In Vitro by the c-Mpl Ligand, Thrombopoietin by Chen, Jichun, Herceg-Harjacek, Lidija, Groopman, Jerome E., Grabarek, Jadwiga

“…Thrombopoietin (TPO) is a recently identified growth factor that regulates megakaryocytopoiesis. Its receptor, c-MpI, is expressed in megakaryocyte…”
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A human serum mannose-binding protein inhibits in vitro infection by the human immunodeficiency virus by EZEKOWITZ, R. A. B, KUHLMAN, M, GROOPMAN, J. E, BYRN, R. A

“…In vitro infection by the human immunodeficiency virus (HIV) of CD4+ H9 lymphoblasts is inhibited by a mannose-binding protein (MBP) purified from human serum…”
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HIV-1 Tat Induces Microvascular Endothelial Apoptosis Through Caspase Activation by Park, In-Woo, Ullrich, Christina K, Schoenberger, Elena, Ganju, Ramesh K, Groopman, Jerome E

“…HIV-1 Tat, in addition to its critical role in viral transcription, is secreted from infected cells and can act as a proto-cytokine. We studied the effects of…”
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The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial by Richman, D D, Fischl, M A, Grieco, M H, Gottlieb, M S, Volberding, P A, Laskin, O L, Leedom, J M, Groopman, J E, Mildvan, D, Hirsch, M S

“…We conducted a double-blind, placebo-controlled trial of oral azidothymidine (AZT) in 282 patients with the acquired immunodeficiency syndrome (AIDS) or…”
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Hematopoietic growth factors. Biology and clinical applications by Groopman, J E, Molina, J M, Scadden, D T

“…The hematopoietic growth factors are potent regulators of blood-cell proliferation and development. The first phase of clinical trials suggests that they may…”
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Impact of Cancer‐Related Fatigue on the Lives of Patients: New Findings From the Fatigue Coalition by Curt, Gregory A., Breitbart, William, Cella, David, Groopman, Jerome E., Horning, Sandra J., Itri, Loretta M., Johnson, David H., Miaskowski, Christine, Scherr, Susan L., Portenoy, Russell K., Vogelzang, Nicholas J.

“…Purpose. This survey was designed to confirm the prevalence and duration of fatigue in the cancer population and to assess its physical, mental, social, and…”
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Production of tumor necrosis factor α and interleukin 1β by monocytic cells infected with human immunodeficiency virus by MOLINA, J.-M, SCADDEN, D. T, BYRN, R, DINARELLO, C. A, GROOPMAN, J. E

“…The production of tumor necrosis factor alpha (TNF alpha) and IL-1 beta by the monocytic cell line THP-1, productively infected with HIV-1, was investigated…”
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The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial by Fischl, M A, Richman, D D, Grieco, M H, Gottlieb, M S, Volberding, P A, Laskin, O L, Leedom, J M, Groopman, J E, Mildvan, D, Schooley, R T

“…We conducted a double-blind, placebo-controlled trial of the efficacy of oral azidothymidine (AZT) in 282 patients with the acquired immunodeficiency syndrome…”
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Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells by AVRAHAM, H, VANNIER, E, COWLEY, S, SHUXIAN JIANG, SHERI CHI, DINARELLO, C. A, ZSEBO, K. M, GROOPMAN, J. E

“…The kit ligand (KL), also termed stem cell factor (SCF), is a recently discovered hematopoietic growth factor that augments response of early progenitor cells…”
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β-Chemokine Receptor CCR5 Signals through SHP1, SHP2, and Syk by Ganju, Ramesh K., Brubaker, Stephanie A., Chernock, Rebecca D., Avraham, Shalom, Groopman, Jerome E.

“…The β-chemokine receptor CCR5 has been shown to modulate cell migration, proliferation, and immune functions and to serve as a co-receptor for the human…”
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Modulation of Megakaryocytopoiesis by Thrombopoietin: The c-Mpl Ligand by Banu, Naheed, Wang, JianFeng, Deng, Bijia, Groopman, Jerome E., Avraham, Hava

“…We have further characterized the biological activities, mechanism of action, and target cell populations of recombinant human and murine thrombopoietin (rhTPO…”
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Identification and characterization of a novel tyrosine kinase from megakaryocytes by Bennett, B D, Cowley, S, Jiang, S, London, R, Deng, B, Grabarek, J, Groopman, J E, Goeddel, D V, Avraham, H

“…Protein-tyrosine kinases play pivotal roles in cell signal transduction. We have isolated a cDNA clone encoding a novel human intracytoplasmic tyrosine kinase,…”
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Characterization of adhesive interactions between human endothelial cells and megakaryocytes by HAVA AVRAHAM, COWLEY, S, CHI, S. Y, SHUXIAN JIANG, GROOPMAN, J. E

“…Cell-cell adhesion is essential for many immunological functions and is believed to be important in the regulation of hematopoiesis. Adhesive interactions…”
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Effect of recombinant human granulocyte-macrophage colony-stimulating factor on myelopoiesis in the acquired immunodeficiency syndrome by Groopman, J E, Mitsuyasu, R T, DeLeo, M J, Oette, D H, Golde, D W

“…We administered recombinant (biosynthetic) human granulocyte-macrophage colony-stimulating factor (GM-CSF) to 16 patients with the acquired immunodeficiency…”
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Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily by BENNETT, B. D, ZHENGYU WANG, WUN-JING KUANG, ANLAI WANG, GROOPMAN, J. E, GOEDDEL, D. V, SCADDEN, D. T

“…Using a polymerase chain reaction based strategy, we identified a novel transmembrane tyrosine kinase in CD34+ human bone marrow cells and a human…”
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Recombinant Human Erythropoietin for Patients with AIDS Treated with Zidovudine by Fischl, Margaret, Galpin, Jeffrey E, Levine, James D, Groopman, Jerome E, Henry, David H, Kennedy, Peter, Miles, Steven, Robbins, William, Starrett, Barbara, Zalusky, Ralph, Abels, Robert I, Tsai, Huei C, Rudnick, Seth A

“…Bone marrow suppression and anemia are frequent side effects of treatment of the acquired immunodeficiency syndrome (AIDS) with zidovudine (formerly…”
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