Search Results - "Grooms, Michael"

A Biochemical Rationale for the Anticancer Effects of Hsp90 Inhibitors: Slow, Tight Binding Inhibition by Geldanamycin and Its Analogues by Gooljarsingh, Lata T., Fernandes, Christine, Yan, Kang, Zhang, Hong, Grooms, Michael, Johanson, Kyung, Sinnamon, Robert H., Kirkpatrick, Robert B., Kerrigan, John, Lewis, Tia, Arnone, Marc, King, Alastair J., Lai, Zhihong, Copeland, Robert A., Tummino, Peter J.

“…Heat shock protein (Hsp)90 is emerging as an important therapeutic target for the treatment of cancer. Two analogues of the Hsp90 inhibitor geldanamycin are…”
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A Second p53 Binding Site in the Central Domain of Mdm2 Is Essential for p53 Ubiquitination by Ma, Jianhong, Martin, John D, Zhang, Hong, Auger, Kurt R, Ho, Thau F, Kirkpatrick, Robert B, Grooms, Michael H, Johanson, Kyung O, Tummino, Peter J, Lai, Zhihong

“…Mdm2 negatively regulates p53 by inhibiting its transcriptional activity and promoting its degradation by functioning as an E3 ubiquitin ligase. The primary…”
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Caries experience associated with attention-deficit/hyperactivity disorder by Grooms, Michael Todd, Keels, Martha Ann, Roberts, Michael W, McIver, F Thomas

“…The purpose of this cross-sectional study was to examine whether children with attention-deficit/hyperactivity disorder (ADHD) had a total caries experience…”
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Crystal structure and substrate specificity of the β‐ketoacyl‐acyl carrier protein synthase III (FabH) from Staphylococcus aureus by Qiu, Xiayang, Choudhry, Anthony E., Janson, Cheryl A., Grooms, Michael, Daines, Robert A., Lonsdale, John T., Khandekar, Sanjay S.

“…β‐Ketoacyl‐ACP synthase III (FabH), an essential enzyme for bacterial viability, catalyzes the initiation of fatty acid elongation by condensing malonyl‐ACP…”
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Bacterial production of biologically active canine interleukin-1β by seamless SUMO tagging and removal by Kirkpatrick, Robert B., Grooms, Michael, Wang, Feilan, Fenderson, Heather, Feild, John, Pratta, Michael A., Volker, Craig, Scott, Gilbert, Johanson, Kyung

“…Interleukin 1β (IL-1β) is a potent stimulator of extracellular matrix degradation in models of osteoarthritis (OA). In contrast to bovine explant models which…”
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A Second p53 Binding Site in the Central Domain of Mdm2 Is Essential for p53 Ubiquitination by Ma, Jianhong, Martin, John D., Zhang, Hong, Auger, Kurt A., Ho, Thau F., Kirkpatrick, Robert B., Grooms, Michael H., Johanson, Kyung O., Tummino, Peter J., Copeland, Robert A., Lai, Zhihong

“…Mdm2 negatively regulates p53 by inhibiting its transcriptional activity and promoting its degradation by functioning as an E3 ubiquitin ligase. The primary…”
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Bacterial production of biologically active canine interleukin-1beta by seamless SUMO tagging and removal by Kirkpatrick, Robert B, Grooms, Michael, Wang, Feilan, Fenderson, Heather, Feild, John, Pratta, Michael A, Volker, Craig, Scott, Gilbert, Johanson, Kyung

“…Interleukin 1beta (IL-1beta) is a potent stimulator of extracellular matrix degradation in models of osteoarthritis (OA). In contrast to bovine explant models…”
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Rhodobacter capsulatus Contains a Novel cb-Type Cytochrome c Oxidase without a CuA Center by Gray, Kevin A, Grooms, Michael, Myllykallio, Hannu, Moomaw, Carolyn, Slaughter, Clive, Daldal, Fevzi

“…The facultative phototrophic bacterium Rhodobacter capsulatus is capable of growth in a wide range of environmental conditions using a highly branched…”
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