Search Results - "Groome, NP"

Activin A and inhibin A as possible endocrine markers for pre-eclampsia by Muttukrishna, S, Knight, P G, Groome, N P, Redman, C W, Ledger, W L

“…Inhibin A and activin A are produced by the placenta during human pregnancy. This study aimed to measure circulating concentrations of inhibin A, pro alpha…”
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Ovarian follicle development in the laying hen is accompanied by divergent changes in inhibin A, inhibin B, activin A and follistatin production in granulosa and theca layers by Lovell, TM, Gladwell, RT, Groome, NP, Knight, PG

“…To study the potential involvement of inhibin A (inhA), inhibin B (inhB), activin A (actA) and follistatin (FS) in the recruitment of follicles into the…”
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Development and validation of a new monoclonal antibody to mammalian aromatase by Turner, KJ, Macpherson, S, Millar, MR, McNeilly, AS, Williams, K, Cranfield, M, Groome, NP, Sharpe, RM, Fraser, HM, Saunders, PT

“…The biosynthesis of oestrogens from androgens is catalysed by the aromatase complex, an essential component of which is the aromatase cytochrome P450 (P450…”
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Anti-Müllerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment by Weenen, Christien, Laven, Joop S E, Von Bergh, Anne R M, Cranfield, Mark, Groome, Nigel P, Visser, Jenny A, Kramer, Piet, Fauser, Bart C J M, Themmen, Axel P N

“…Anti-Müllerian hormone (AMH) is a member of the transforming growth factor-beta superfamily, which plays an important role in both ovarian primordial follicle…”
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Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin by Evans, LW, Muttukrishna, S, Groome, NP

“…Recent studies have found follistatin to be an important regulator of activin bioactivity. Whilst a number of assay formats have been described, all are of…”
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Increased maternal serum activin A but not follistatin levels in pregnant women with hypertensive disorders by D'Antona, D, Reis, FM, Benedetto, C, Evans, LW, Groome, NP, de Kretser, DM, Wallace, EM, Petraglia, F

“…Activin A levels are elevated in maternal serum of pregnant women with hypertensive disturbances. Because follistatin is a circulating binding protein for…”
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Myostatin Inhibits Myogenesis and Promotes Adipogenesis in C3H 10T(1/2) Mesenchymal Multipotent Cells by Artaza, Jorge N, Bhasin, Shalender, Magee, Thomas R, Reisz-Porszasz, Suzanne, Shen, Ruoquin, Groome, Nigel P, Fareez, Meerasaluh M, Gonzalez-Cadavid, Nestor F

“…Inactivating mutations of the mammalian myostatin gene are associated with increased muscle mass and decreased fat mass; conversely, myostatin transgenic mice…”
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Temporal and hormonal regulation of inhibin protein and subunit mRNA expression by post-natal and immature rat ovaries by Drummond, AE, Dyson, M, Thean, E, Groome, NP, Robertson, DM, Findlay, JK

“…The contribution of specific follicle populations to dimeric inhibin production and inhibin subunit mRNA expression by the rat ovary has been investigated in…”
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Anti-Müllerian Hormone Protein Expression Is Reduced during the Initial Stages of Follicle Development in Human Polycystic Ovaries by Stubbs, Sharron A, Hardy, Kate, Da Silva-Buttkus, Patricia, Stark, Jaroslav, Webber, Lisa J, Flanagan, Adrienne M, Themmen, Axel P. N, Visser, Jenny A, Groome, Nigel P, Franks, Stephen

“…CONTEXT:Polycystic ovary syndrome, the most common cause of anovulatory infertility, is characterized by disordered folliculogenesis, notably increased…”
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Steroid Receptor Expression in Uterine Natural Killer Cells by Henderson, Teresa A., Saunders, Philippa T. K., Moffett-King, Ashley, Groome, Nigel P., Critchley, Hilary O. D.

“…The endometrium contains a unique subset of uterine-specific natural killer (uNK) cells, the proposed functions of which include a role in decidualization,…”
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Growth Differentiation Factor 9 and Bone Morphogenetic Protein 15 Are Essential for Ovarian Follicular Development in Sheep by JUENGEL, Jennifer L, HUDSON, Norma L, RITVOS, Olli, MCNATTY, Kenneth P, HEATH, Derek A, SMITH, Peter, READER, Karen L, LAWRENCE, Steve B, O'CONNELL, Anne R, LAITINEN, Mika P. E, CRANFIELD, Mark, GROOME, Nigel P

“…The aim of this study was to test the hypothesis that both growth differential factor 9 (GDF9) and bone morphogenetic protein (BMP15; also known as GDF9B) are…”
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Comparative effects of neonatal exposure of male rats to potent and weak (environmental) estrogens on spermatogenesis at puberty and the relationship to adult testis size and fertility: evidence for stimulatory effects of low estrogen levels by Atanassova, N, McKinnell, C, Turner, K J, Walker, M, Fisher, J S, Morley, M, Millar, M R, Groome, N P, Sharpe, R M

“…This study investigated whether neonatal exposure of male rats to estrogenic compounds altered pubertal spermatogenesis (days 18 and 25) and whether the…”
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Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function in ruminants by McNatty, Kenneth P, Juengel, Jennifer L, Reader, Karen L, Lun, Stan, Myllymaa, Samu, Lawrence, Steve B, Western, Andrea, Meerasahib, Mohamed F, Mottershead, David G, Groome, Nigel P, Ritvos, Olli, Laitinen, Mika P E

“…The oocyte-secreted polypeptide growth factors, growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15, also known as GDF9B) have both…”
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Oocyte-expressed genes affecting ovulation rate by McNatty, K.P., Smith, P., Moore, L.G., Reader, K., Lun, S., Hanrahan, J.P., Groome, N.P., Laitinen, M., Ritvos, O., Juengel, J.L.

“…From examination of inherited patterns of ovulation rate in sheep, several breeds have been identified with point mutations in two growth factor genes (BMP15…”
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Modulatory effects of gonadotrophins and insulin-like growth factor on the secretion of inhibin A and progesterone by granulosa cells from chicken preovulatory (F1-F3) follicles by Lovell, TM, Gladwell, RT, Groome, NP, Knight, PG

“…The aim of this study was to compare the actions and interactions of gonadotrophins (LH and FSH) and an analogue of insulin-like growth factor I (LR3-IGF-I) on…”
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Relationship between male reproductive hormones, sperm DNA damage and markers of oxidative stress in infertility by Appasamy, M, Muttukrishna, S, Pizzey, AR, Ozturk, O, Groome, NP, Serhal, P, Jauniaux, E

“…Abstract This study investigated the relationship between male reproductive hormones and sperm DNA damage and markers of oxidative stress in men undergoing…”
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Measurement of dimeric inhibin B throughout the human menstrual cycle by Groome, N P, Illingworth, P J, O'Brien, M, Pai, R, Rodger, F E, Mather, J P, McNeilly, A S

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Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function by McNatty, Kenneth P, Juengel, Jennifer L, Reader, Karen L, Lun, Stan, Myllymaa, Samu, Lawrence, Steve B, Western, Andrea, Meerasahib, Mohamed F, Mottershead, David G, Groome, Nigel P, Ritvos, Olli, Laitinen, Mika P E

“…The oocyte-secreted polypeptide growth factors, growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15, also known as GDF9B) have both…”
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Development of a sensitive enzyme immunoassay for anti-Müllerian hormone and the evaluation of potential clinical applications in males and females by Al-Qahtani, A., Muttukrishna, S., Appasamy, M., Johns, J., Cranfield, M., Visser, J. A., Themmen, A. P. N., Groome, N. P.

“…Summary Background and objective  Recent studies have found anti‐Müllerian hormone (AMH) to be a potentially important marker for the assessment of ovarian…”
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Permanent effects of neonatal estrogen exposure in rats on reproductive hormone levels, Sertoli cell number, and the efficiency of spermatogenesis in adulthood by Atanassova, N, McKinnell, C, Walker, M, Turner, K J, Fisher, J S, Morley, M, Millar, M R, Groome, N P, Sharpe, R M

“…This study aimed to identify the mechanism(s) for impairment of spermatogenesis in adulthood in rats treated neonatally with estrogens. Rats were treated (days…”
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