Search Results - "Gronowitz, Simon"

Circulating Tumor M2 Pyruvate Kinase and Thymidine Kinase 1 Are Potential Predictors for Disease Recurrence in Renal Cell Carcinoma After Nephrectomy by Nisman, Benjamin, Yutkin, Vladimir, Nechushtan, Hovav, Gofrit, Ofer N, Peretz, Tamar, Gronowitz, Simon, Pode, Dov

“…Objectives Pyruvate kinase type M2 (TuM2-PK) and thymidine kinase 1 (TK1) are the key enzymes involved in tumor cells metabolism and proliferation. We explored…”
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Analysis of thymidine kinase serum levels by novel method DiviTum in multiple myeloma and monoclonal gammopathy of undetermined significance - comparison with imaging methods 99mTc-MIBI scintigraphy and 18F-FDG PET/CT by Bacovsky, Jaroslav, Myslivecek, Miroslav, Minarik, Jiri, Scudla, Vlastimil, Pika, Tomas, Zapletalova, Jana, Petrova, Pavla, Bartkova, Margita, Adam, Tomas, Gronowitz, Simon J

“…The study aimed at comparing two methods for evaluating thymidinekinase TK in serum - an older RIA method and novel DiviTum - in patients with MM and MGUS, and…”
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Comparison of Two Human Immunodeficiency Virus (HIV) RNA Surrogate Assays to the Standard HIV RNA Assay by Jennings, Cheryl, Fiscus, Susan A, Crowe, Suzanne M, Danilovic, Aleksandra D, Morack, Ralph J, Scianna, Salvatore, Cachafeiro, Ada, Brambilla, Donald J, Schupbach, Jorg, Stevens, Wendy, Respess, Richard, Varnier, Oliviero E, Corrigan, Gary E, Gronowitz, J. Simon, Ussery, Michael A, Bremer, James W

“…Human immunodeficiency virus (HIV) RNA testing is the gold standard for monitoring antiretroviral therapy in HIV-infected patients. However, equipment and…”
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Serum thymidine kinase 1 activity in the prognosis and monitoring of chemotherapy in lung cancer patients: a brief report by Nisman, Benjamin, Nechushtan, Hovav, Biran, Haim, Gantz-Sorotsky, Hadas, Peled, Nir, Gronowitz, Simon, Peretz, Tamar

“…Thymidine kinase 1 (TK1) is a metabolic enzyme involved in DNA synthesis. Most standard treatment protocols for lung cancer (LC) include cytotoxic agents,…”
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Alternative approach to blood screening using the ExaVir reverse transcriptase activity assay by Seyoum, Elizabeth, Wolday, Dawit, Mekonen, Teferi, Girma, Mulu, Meselle, Tsehaynesh, Källander, Clas, Gronowitz, Simon, Britton, Sven

“…408 non-selected samples were obtained from healthy, adult individuals donating blood at the Ethiopian Red Cross Society-National Blood Transfusion Service…”
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Preoperative Serum Thymidine Kinase Activity as Novel Monitoring, Prognostic, and Predictive Biomarker in Pancreatic Cancer by Felix, Klaus, Hinz, Ulf, Dobiasch, Sophie, Hackert, Thilo, Bergmann, Frank, Neumüller, Magnus, Gronowitz, Simon, Bergqvist, Mattias, Strobel, Oliver

“…The aim of the study was to investigate serum thymidine kinase 1 (S-TK) activity as a diagnostic and prognostic marker for patients with pancreatic ductal…”
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Comparison of diagnostic and prognostic performance of two assays measuring thymidine kinase 1 activity in serum of breast cancer patients by Nisman, Benjamin, Allweis, Tanir, Kadouri, Luna, Mali, Bela, Hamburger, Tamar, Baras, Mario, Gronowitz, Simon, Peretz, Tamar

“…We compared two recently developed immunoassays for serum thymidine kinase 1 (TK1) activity: one manual assay (DiviTum, Biovica(®)) and one fully automated…”
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Increased Proliferative Background in Healthy Women with BRCA1/2 Haploinsufficiency Is Associated with High Risk for Breast Cancer by NISMAN, Benjamin, KADOURI, Luna, ALLWEIS, Tanir, MALY, Bella, HAMBURGER, Tamar, GRONOWITZ, Simon, PERETZ, Tamar

“…Previous studies indicated that BRCA haploinsufficiency was associated with activation of the EGF receptor (EGFR) signaling pathway and increased proliferative…”
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Significance of amino acid substitutions in the thymidine kinase gene of herpes simplex virus type 1 for resistance by Sauerbrei, Andreas, Liermann, Kristin, Bohn, Kathrin, Henke, Andreas, Zell, Roland, Gronowitz, Simon, Wutzler, Peter

“…► Report of methods to clarify significance of amino acid changes in HSV-1 TK gene. ► Recombinant proteins were synthesized after cloning and site-directed…”
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Total Cell Division The Ultimate Biomarker for Personalized Medicine in Cancer? Updated Technology and Novel Clinical Results by Gronowitz, S.J., Nisman, B., Peretz-Yablonski, T.

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Use of HIV-1 reverse transcriptase recovered from human plasma for phenotypic drug susceptibility testing by Shao, Xing-Wu, Malmsten, A, Lennerstrand, J, Soennerborg, A, Unge, T, Simon Gronowitz, J, Kaellander, CFR

“…To demonstrate the use of HIV-1 reverse transcriptase (RT) recovered directly from plasma for phenotypic drug susceptibility testing. Plasma from HIV-1…”
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Screening of herpes simplex virus type 1 isolates for acyclovir resistance using DiviTum® assay by Sauerbrei, Andreas, Vödisch, Susanne, Bohn, Kathrin, Schacke, Michael, Gronowitz, Simon

“…Rapid alternative methods are required to evaluate easily acyclovir (ACV) sensitivity of clinical herpes simplex virus (HSV) isolates. The objective of this…”
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Total body cell division the ultimate biomarker for personalized medicine in cancer? by Gronowitz, Simon, Nisman, B., Peretz, Tamar

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HIV-1 viral load determination based on reverse transcriptase activity recovered from human plasma by Malmsten, Anders, Shao, Xing-Wu, Aperia, Kajsa, Corrigan, Gary E., Sandström, Eric, Källander, Clas F.R., Leitner, Thomas, Gronowitz, J. Simon

“…We describe a procedure (ExaVir™ Load) to carry out human immunodeficiency virus‐1 (HIV‐1) viral load testing using reverse transcriptase (RT) recovered from…”
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Reverse transcriptase activity for quantitation of HIV-1 subtype C in plasma: Relation to RNA copy number and CD4 T-cell count by Seyoum, Elizabeth, Wolday, Dawit, Girma, Mulu, Malmsten, Anders, Meselle, Tsehaynesh, Gronowitz, J. Simon, Britton, Sven

“…The present study monitored the changes in human immunodeficiency virus (HIV) viral load using a reverse transcriptase (RT) assay and an HIV‐1 RNA based assay,…”
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Improved HIV-1 viral load determination based on reverse transcriptase activity recovered from human plasma by Malmsten, Anders, Shao, Xing-Wu, Sjödahl, Staffan, Fredriksson, Eva-Lena, Pettersson, Ingvar, Leitner, Thomas, Källander, Clas F.R., Sandström, Eric, Gronowitz, J. Simon

“…A more sensitive version of ExaVir Load, a test that utilizes reverse transcriptase (RT) activity from virions in plasma to determine HIV‐1 viral load, is…”
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Serum thymidine kinase 1 activity in breast cancer by Nisman, Benjamin, Allweis, Tanir, Kaduri, Luna, Maly, Bella, Gronowitz, Simon, Hamburger, Tamar, Peretz, Tamar

“…Thymidine kinase 1 (TK1) is an enzyme involved in DNA synthesis and an important proliferation marker. We explored the association of preoperative serum TK1…”
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Evaluation of thymidine kinase 1 activity in the serum of lung cancer (LC) patients by Nisman, B., Nechushtan, H., Biran, H., Gronowitz, Simon, Peretz, T.

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Use of HIV-1 reverse transcriptase recovered from human plasma for phenotypic drug susceptibility testing by SHAO, Xing-Wu, MALMSTEN, Anders, LENNERSTRAND, Johan, SÖNNERBORG, Anders, UNGEE, Torsten, GRONOWITZ, J. Simon, KÄLLANDER, Clas F. R

“…To demonstrate the use of HIV-1 reverse transcriptase (RT) recovered directly from plasma for phenotypic drug susceptibility testing. Plasma from HIV-1…”
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Proliferative background in healthy women carriers of BRCA1/2 mutation by Nisman, B., Kadouri, L., Allweis, T., Hamburger, T., Gronowitz, Simon, Peretz, T.

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