Search Results - "Gronenschild, Ed H.B.M."

Decreased gray matter diffusivity: A potential early Alzheimer’s disease biomarker? by Jacobs, Heidi I.L, van Boxtel, Martin P.J, Gronenschild, Ed H.B.M, Uylings, Harry B.M, Jolles, Jelle, Verhey, Frans R.J

“…Abstract Background Gray matter atrophy, an important biomarker for early Alzheimer’s disease, might be due to white matter changes within gray matter. Methods…”
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White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed by Freeze, Whitney M., Jacobs, Heidi I.L., de Jong, Joost J., Verheggen, Inge C.M., Gronenschild, Ed H.B.M., Palm, Walter M., Hoff, Erik I., Wardlaw, Joanna M., Jansen, Jacobus F.A., Verhey, Frans R., Backes, Walter H.

“…Blood-brain barrier (BBB) leakage is considered an important underlying process in both cerebral small vessel disease (cSVD) and Alzheimer's disease (AD). The…”
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Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan: A 7 T imaging study by Riphagen, Joost M., Schmiedek, Lisa, Gronenschild, Ed H. B. M., Yassa, Michael A., Priovoulos, Nikos, Sack, Alexander T., Verhey, Frans R. J., Jacobs, Heidi I. L.

“…Pattern separation (PS) describes the process by which the brain discriminates similar stimuli from previously encoded stimuli. This fundamental process…”
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Relevance of parahippocampal-locus coeruleus connectivity to memory in early dementia by Jacobs, Heidi I.L, Wiese, Svenja, van de Ven, Vincent, Gronenschild, Ed H.B.M, Verhey, Frans R.J, Matthews, Paul M

“…Abstract Neuropathology suggests an important role for the locus coeruleus (LC) in Alzheimer's disease (AD) pathophysiology. Neuropathology and structural…”
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Increased Aortic Pulse Wave Velocity Is Associated With Silent Cerebral Small-Vessel Disease in Hypertensive Patients by Henskens, Léon H.G, Kroon, Abraham A, van Oostenbrugge, Robert J, Gronenschild, Ed H.B.M, Fuss-Lejeune, Monique M.J.J, Hofman, Paul A.M, Lodder, Jan, de Leeuw, Peter W

“…Aortic stiffness predicts an excess risk of stroke, supposedly via cerebral small-vessel disease. White matter hyperintensities, silent lacunar infarcts, and…”
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Can FreeSurfer Compete with Manual Volumetric Measurements in Alzheimer's Disease? by Clerx, Lies, Gronenschild, Ed H B M, Echavarri, Carmen, Verhey, Frans, Aalten, Pauline, Jacobs, Heidi I L

“…Alzheimer's disease-related pathology results in tremendous structural and functional changes in the brain. These morphological changes might lead to a less…”
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Specific cerebellar grey matter volume loss is predictive for episodic memory retrieval deficits in early Alzheimer's disease by Jacobs, Heidi, Gronenschild, Ed H.B.M, Clerx, Lies, Aalten, Pauline, Verhey, Frans R.J

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RELEVANCE OF PARAHIPPOCAMPAL-LOCUS COERULEUS CONNECTIVITY TO MEMORY DYSFUNCTION IN EARLY ALZHEIMER'S DISEASE by Jacobs, Heidi I.L, Wiese, Svenja, van de Ven, Vincent, Gronenschild, Ed H.B.M, Verhey, Frans R.J, Matthews, Paul M

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RELEVANCE OF PARAHIPPOCAMPAL-LOCUS COERULEUS CONNECTIVITY TO MEMORY DYSFUNCTION IN EARLY ALZHEIMER'S DISEASE by Jacobs, Heidi I.L, Wiese, Svenja, van de Ven, Vincent, Gronenschild, Ed H.B.M, Verhey, Frans R.J, Matthews, Paul M

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A time-saving and facilitating approach for segmentation of anatomically defined cortical regions: MRI volumetry by Gronenschild, Ed H.B.M, Burgmans, Saartje, Smeets, Floortje, Vuurman, Eric F.P.M, Uylings, Harry B.M, Jolles, Jelle

“…Abstract In this study, we present an accurate, reliable, robust, and time-efficient technique for a semi-automatic segmentation of neuroanatomically defined…”
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Patterns of gray and white matter changes in individuals at risk for Alzheimer's disease by Jacobs, Heidi I L, van Boxtel, Martin P J, Gronenschild, Ed H B M, Williams, Victoria J, Burgmans, Saartje, Uylings, Harry B M, Jolles, Jelle, Verhey, Frans R J

“…Structural brain changes precede cognitive and clinical symptoms in Alzheimer's disease (AD). We aimed to examine the gray and white matter tissue changes in…”
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IC-P1-032: The parietal and prefrontal lobe are characterized by dissimilar age-related atrophy patterns by Jacobs, Heidi I.L, Van Boxtel, Martin P.J, Gronenschild, Ed H.B.M, Smeets, Floortje, Burgmans, Saartje, Uylings, Harry B.M, Verhey, Frans R.J, Jolles, Jelle

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The effects of FreeSurfer version, workstation type, and Macintosh operating system version on anatomical volume and cortical thickness measurements by Gronenschild, Ed H B M, Habets, Petra, Jacobs, Heidi I L, Mengelers, Ron, Rozendaal, Nico, van Os, Jim, Marcelis, Machteld

“…FreeSurfer is a popular software package to measure cortical thickness and volume of neuroanatomical structures. However, little if any is known about…”
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Increase in blood–brain barrier leakage in healthy, older adults by Verheggen, Inge C. M., de Jong, Joost J. A., van Boxtel, Martin P. J., Gronenschild, Ed H. B. M., Palm, Walter M., Postma, Alida A., Jansen, Jacobus F. A., Verhey, Frans R. J., Backes, Walter H.

“…Blood–brain barrier (BBB) breakdown can disrupt nutrient supply and waste removal, which affects neuronal functioning. Currently, dynamic contrast-enhanced…”
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Microvascular Phenotyping in the Maastricht Study: Design and Main Findings, 2010–2018 by Li, Wenjie, Schram, Miranda T, Sörensen, Ben M, van Agtmaal, Marnix J M, Berendschot, Tos T J M, Webers, Carroll A B, Jansen, Jacobus F A, Backes, Walter H, Gronenschild, Ed H B M, Schalkwijk, Casper G, Stehouwer, Coen D A, Houben, Alfons J H M

“…Abstract Microvascular dysfunction (MVD) is a common pathophysiological change that occurs in various diseases, such as type 2 diabetes mellitus (T2DM), heart…”
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Associations of increased interstitial fluid with vascular and neurodegenerative abnormalities in a memory clinic sample by van der Thiel, Merel M., Freeze, Whitney M., Verheggen, Inge C.M., Wong, Sau May, de Jong, Joost J.A., Postma, Alida A., Hoff, Erik I., Gronenschild, Ed H.B.M., Verhey, Frans R., Jacobs, Heidi I.L., Ramakers, Inez H.G.B., Backes, Walter H., Jansen, Jacobus F.A.

“…The vascular and neurodegenerative processes related to clinical dementia cause cell loss which induces, amongst others, an increase in interstitial fluid…”
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Capillary Rarefaction Associates with Albuminuria: The Maastricht Study by Martens, Remy J H, Henry, Ronald M A, Houben, Alfons J H M, van der Kallen, Carla J H, Kroon, Abraham A, Schalkwijk, Casper G, Schram, Miranda T, Sep, Simone J S, Schaper, Nicolaas C, Dagnelie, Pieter C, Muris, Dennis M J, Gronenschild, Ed H B M, van der Sande, Frank M, Leunissen, Karel M L, Kooman, Jeroen P, Stehouwer, Coen D A

“…Albuminuria may be a biomarker of generalized (i.e., microvascular and macrovascular) endothelial dysfunction. According to this concept, endothelial…”
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Shades of white: diffusion properties of T1- and FLAIR-defined white matter signal abnormalities differ in stages from cognitively normal to dementia by Riphagen, Joost M., Gronenschild, Ed H.B.M., Salat, David H., Freeze, Whitney M., Ivanov, Dimo, Clerx, Lies, Verhey, Frans R.J., Aalten, Pauline, Jacobs, Heidi I.L.

“…The underlying pathology of white matter signal abnormalities (WMSAs) is heterogeneous and may vary dependent on the magnetic resonance imaging contrast used…”
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Contributions of Cerebro-Cerebellar Default Mode Connectivity Patterns to Memory Performance in Mild Cognitive Impairment by Pagen, Linda H G, van de Ven, Vincent G, Gronenschild, Ed H B M, Priovoulos, Nikos, Verhey, Frans R J, Jacobs, Heidi I L

“…The cerebral default mode network (DMN) can be mapped onto specific regions in the cerebellum, which are specifically vulnerable to atrophy in Alzheimer's…”
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Default mode network connectivity as a function of familial and environmental risk for psychotic disorder by Peeters, Sanne C T, van de Ven, Vincent, Gronenschild, Ed H B M, Patel, Ameera X, Habets, Petra, Goebel, Rainer, van Os, Jim, Marcelis, Machteld

“…Research suggests that altered interregional connectivity in specific networks, such as the default mode network (DMN), is associated with cognitive and…”
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