Search Results - "Grondin, Jensine A"
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Mucins in Intestinal Mucosal Defense and Inflammation: Learning From Clinical and Experimental Studies
Published in Frontiers in immunology (04-09-2020)“…Throughout the gastrointestinal (GI) tract, a distinct mucus layer composed of highly glycosylated proteins called mucins plays an essential role in providing…”
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Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice
Published in Nature communications (20-12-2022)“…Chemicals in food are widely used leading to significant human exposure. Allura Red AC (AR) is a highly common synthetic colorant; however, little is known…”
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Interaction between Intestinal Parasites and the Gut Microbiota: Implications for the Intestinal Immune Response and Host Defence
Published in Pathogens (Basel) (23-07-2024)“…Intestinal parasites, including helminths and protozoa, account for a significant portion of the global health burden. The gastrointestinal (GI) tract not only…”
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Tryptophan‐derived serotonin‐kynurenine balance in immune activation and intestinal inflammation
Published in The FASEB journal (01-10-2021)“…Endogenous tryptophan metabolism pathways lead to the production of serotonin (5‐hydroxytryptamine; 5‐HT), kynurenine, and several downstream metabolites which…”
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Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis
Published in Nature immunology (01-12-2022)“…Aside from centrally induced trained immunity in the bone marrow (BM) and peripheral blood by parenteral vaccination or infection, evidence indicates that…”
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Emerging Roles of Gut Serotonin in Regulation of Immune Response, Microbiota Composition and Intestinal Inflammation
Published in Journal of the Canadian Association of Gastroenterology (01-02-2024)“…Abstract Although the exact etiology of inflammatory bowel diseases (IBD) is unknown, studies have shown that dysregulated immune responses, genetic factors,…”
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Novel 5-HT 7 receptor antagonists modulate intestinal immune responses and reduce severity of colitis
Published in American journal of physiology: Gastrointestinal and liver physiology (01-07-2024)“…Inflammatory bowel disease (IBD) encompasses several debilitating chronic gastrointestinal (GI) inflammatory disorders, including Crohn's disease and…”
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Author Correction: Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis
Published in Nature immunology (01-06-2023)Get full text
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