Search Results - "Gronbach, Leonie"

Primary Extracellular Matrix Enables Long-Term Cultivation of Human Tumor Oral Mucosa Models by Gronbach, Leonie, Jurmeister, Philipp, Schäfer-Korting, Monika, Keilholz, Ulrich, Tinhofer, Ingeborg, Zoschke, Christian

“…3D tumor models clearly outperform 2D cell cultures in recapitulating tissue architecture and drug response. However, their potential in understanding…”
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Automated Real-Time Tumor Pharmacokinetic Profiling in 3D Models: A Novel Approach for Personalized Medicine by Joseph, Jan F, Gronbach, Leonie, García-Miller, Jill, Cruz, Leticia M, Wuest, Bernhard, Keilholz, Ulrich, Zoschke, Christian, Parr, Maria K

“…Cancer treatment often lacks individual dose adaptation, contributing to insufficient efficacy and severe side effects. Thus, personalized approaches are…”
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Organotypic Head and Neck Cancer Models for Advanced Preclinical Drug Testing by Gronbach, Leonie

“…Epidemiology Head and neck cancer is the seventh most common cancer type and the seventh most frequent cause of death from cancer with 890,000 new cases and…”
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A multilayered epithelial mucosa model of head neck squamous cell carcinoma for analysis of tumor-microenvironment interactions and drug development by Gronbach, Leonie, Wolff, Christopher, Klinghammer, Konrad, Stellmacher, Johannes, Jurmeister, Philipp, Alexiev, Ulrike, Schäfer-Korting, Monika, Tinhofer, Ingeborg, Keilholz, Ulrich, Zoschke, Christian

“…Pharmacotherapy of head and neck squamous cell carcinoma (HNSCC) often fails due to the development of chemoresistance and severe systemic side effects of…”
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