Search Results - "Gromme, Monique"

Multicenter study to evaluate a new enumeration method for hematopoietic stem cell collection management by Grommé, Monique, Russcher, Henk, Braakman, Eric, Klinkspoor, J. Henriëtte, Dobber, Johan A., de Greef, Inge, de Wit, Norbert C.J.

“…BACKGROUND CD34 flow cytometry is the gold standard for stem cell enumeration in peripheral blood at the mobilization stage and in the final apheresis product…”
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The major substrates for TAP in vivo are derived from newly synthesized proteins by Reits, Eric A. J, Vos, Jan C, Grommé, Monique, Neefjes, Jacques

“…The transporter associated with antigen processing (TAP) is a member of the family of ABC transporters that translocate a large variety of substrates across…”
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Recycling MHC Class I Molecules and Endosomal Peptide Loading by Gromme, Monique, Fons G. C. M. Uytdehaag, Janssen, Hans, Calafat, Jero, Van Binnendijk, Robert S., Marcel J. H. Kenter, Tulp, Abraham, Verwoerd, Desiree, Neefjes, Jacques

“…MHC class I molecules usually present peptides derived from endogenous antigens that are bound in the endoplasmic reticulum. Loading of exogenous antigens on…”
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Allelic Differences in the Relationship Between Proteasome Activity and MHC Class I Peptide Loading by Benham, Adam M, Gromme, Monique, Neefjes, Jacques

“…MHC class I molecules are cell surface glycoproteins that play a pivotal role in the response to intracellular pathogens. The loading of MHC class I molecules…”
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Antigen degradation or presentation by MHC class I molecules via classical and non-classical pathways by Grommé, Monique, Neefjes, Jacques

“…Major histocompatibility complex (MHC) class I molecules usually present endogenous peptides at the cell surface. This is the result of a cascade of events…”
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Recycling MHC class 1 molecules and endosomal peptide loading by Gromme, Monique, Uytdehaag, Fons G C M, Janssen, Hans, Calafat, Jero

“…MHC class I molecules usually present peptides derived from endogenous antigens that are bound in the endoplasmic reticulum. Loading of exogenous antigens on…”
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Differential effects of Viscum album extract IscadorQu on cell cycle progression and apoptosis in cancer cells by Harmsma, Marjan, Grommé, Monique, Ummelen, Monique, Dignef, Wendy, Tusenius, Karel Jan, Ramaekers, Frans C S

“…Extracts from European mistletoe or Viscum album L. have been reported to exert cytotoxic and immunomodulatory effects in vitro and in vivo. The mechanism of…”
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Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling by Roelse, J, Grommé, M, Momburg, F, Hämmerling, G, Neefjes, J

“…Cytosolic peptides are translocated to the endoplasmic reticulum (ER) lumen by the transporters associated with antigen processing (TAP), where major…”
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Analysis of the fine specificity of rat, mouse and human TAP peptide transporters by Neefjes, J, Gottfried, E, Roelse, J, Grommé, M, Obst, R, Hämmerling, G J, Momburg, F

“…Prior to their association with major histocompatibility complex (MHC) class I molecules, peptides generated from cytosolic antigens need to be translocated by…”
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The rational design of TAP inhibitors using peptide substrate modifications and peptidomimetics by Grommé, M, van der Valk, R, Sliedregt, K, Vernie, L, Liskamp, R, Hämmerling, G, Koopmann, J O, Momburg, F, Neefjes, J

“…The major histocompatibility complex (MHC)-encoded transporter associated with antigen processing (TAP) translocates peptides from the cytosol into the lumen…”
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