Search Results - "Gromadski, Kirill B"

Kinetic Determinants of High-Fidelity tRNA Discrimination on the Ribosome by Gromadski, Kirill B., Rodnina, Marina V.

“…The ribosome selects aminoacyl-tRNA (aa-tRNA) matching to the mRNA codon from the bulk of nonmatching aa-tRNAs in two consecutive selection steps, initial…”
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A Uniform Response to Mismatches in Codon-Anticodon Complexes Ensures Ribosomal Fidelity by Gromadski, Kirill B., Daviter, Tina, Rodnina, Marina V.

“…Ribosomes take an active part in aminoacyl-tRNA selection by distinguishing correct and incorrect codon-anticodon pairs. Correct codon-anticodon complexes are…”
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Recognition and selection of tRNA in translation by Rodnina, Marina V., Gromadski, Kirill B., Kothe, Ute, Wieden, Hans-Joachim

“…Aminoacyl-tRNA (aa-tRNA) is delivered to the ribosome in a ternary complex with elongation factor Tu (EF-Tu) and GTP. The stepwise movement of aa-tRNA from…”
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Kinetic Mechanism of Elongation Factor Ts-Catalyzed Nucleotide Exchange in Elongation Factor Tu by Gromadski, Kirill B, Wieden, Hans-Joachim, Rodnina, Marina V

“…The interaction of Escherichia coli elongation factor Tu (EF-Tu) with elongation factor Ts (EF-Ts) and guanine nucleotides was studied by the stopped-flow…”
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Mechanism of EF-Ts-Catalyzed Guanine Nucleotide Exchange in EF-Tu:  Contribution of Interactions Mediated by Helix B of EF-Tu by Schümmer, Tobias, Gromadski, Kirill B, Rodnina, Marina V

“…Elongation factor Tu (EF-Tu) belongs to the family of GTP-binding proteins and requires elongation factor Ts (EF-Ts) for nucleotide exchange. Crystal…”
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Streptomycin interferes with conformational coupling between codon recognition and GTPase activation on the ribosome by Rodnina, Marina V, Gromadski, Kirill B

“…Aminoacyl-tRNAs (aa-tRNAs) are selected by the ribosome through a kinetically controlled induced fit mechanism. Cognate codon recognition induces a…”
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Kinetics of the Interactions between Yeast Elongation Factors 1A and 1Bα, Guanine Nucleotides, and Aminoacyl-tRNA by Gromadski, Kirill B., Schümmer, Tobias, Strømgaard, Anne, Knudsen, Charlotte R., Kinzy, Terri Goss, Rodnina, Marina V.

“…The interactions of elongation factor 1A (eEF1A) from Saccharomyces cerevisiae with elongation factor 1Bα (eEF1Bα), guanine nucleotides, and aminoacyl-tRNA…”
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Towards understanding selenocysteine incorporation into bacterial proteins by Fischer, Niels, Paleskava, Alena, Gromadski, Kirill B, Konevega, Andrey L, Wahl, Markus C, Stark, Holger, Rodnina, Marina V

“…In bacteria, UGA stop codons can be recoded to direct the incorporation of selenocysteine into proteins on the ribosome. Recoding requires a selenocysteine…”
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Kinetics of the interactions between yeast elongation factors 1A and 1Balpha, guanine nucleotides, and aminoacyl-tRNA by Gromadski, Kirill B, Schümmer, Tobias, Strømgaard, Anne, Knudsen, Charlotte R, Kinzy, Terri Goss, Rodnina, Marina V

“…The interactions of elongation factor 1A (eEF1A) from Saccharomyces cerevisiae with elongation factor 1Balpha (eEF1Balpha), guanine nucleotides, and…”
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Kinetics of the Interactions between Yeast Elongation Factors 1A and 1Bα, Guanine Nucleotides, and Aminoacyl-tRNA by Kirill B. Gromadski, Tobias Schümmer, Anne Strømgaard, Charlotte R. Knudsen, Terri Goss Kinzy, Marina V. Rodnina

“…The interactions of elongation factor 1A (eEF1A) from Saccharomyces cerevisiae with elongation factor 1Bα (eEF1Bα), guanine nucleotides, and aminoacyl-tRNA…”
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Substrate Selection and Peptide Bond Formation by the Ribosome by Rodnina, Marina V., Kothe, Ute, Beringer, Malte, Gromadski, Kirill B., Bieling, Peter

“…The ribosome recognizes aminoacyl‐tRNA through shape discrimination of the codon‐anticodon duplex and regulates the rates of GTP hydrolysis by EF‐Tu and…”
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