Search Results - "Groger, Harald"

Where Chemocatalysis Meets Biocatalysis: In Water by Gröger, Harald, Gallou, Fabrice, Lipshutz, Bruce H.

“…Chemoenzymatic catalysis, by definition, involves the merging of sequential reactions using both chemocatalysis and biocatalysis, typically in a single…”
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Combining the ‘two worlds’ of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media by Gröger, Harald, Hummel, Werner

“…•Combining the “two worlds” biocatalysis and chemocatalysis towards one-pot syntheses in aqueous media is a promising concept for the development of both…”
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Cooperative Catalysis of Noncompatible Catalysts through Compartmentalization: Wacker Oxidation and Enzymatic Reduction in a One-Pot Process in Aqueous Media by Sato, Hirofumi, Hummel, Werner, Gröger, Harald

“…A Wacker oxidation using CuCl/PdCl2 as a catalyst system was successfully combined with an enzymatic ketone reduction to convert styrene enantioselectively…”
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Catalytic Enantioselective Strecker Reactions and Analogous Syntheses by Groger, Harald

“…The Strecker reaction which was reported already in 1850 is the oldest known synthesis of alpha-amino acids. This reaction comprises a condensation of an…”
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Cyanide-Free Enantioselective Catalytic Strategies for the Synthesis of Chiral Nitriles by Gröger, Harald, Asano, Yasuhisa

“…The development of enantioselective syntheses of nitriles gained increasing interest due to, e.g., an increasing demand for chiral nitriles for drug synthesis…”
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Strategies for regeneration of nicotinamide coenzymes emphasizing self-sufficient closed-loop recycling systems by Hummel, Werner, Gröger, Harald

“…•Different strategies to regenerate the reduced coenzymes NAD(P)H are presented.•Besides two standard methods this contribution focusses on a further method…”
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The function of the oxylipin 12-oxophytodienoic acid in cell signaling, stress acclimation, and development by Maynard, Daniel, Gröger, Harald, Dierks, Thomas, Dietz, Karl-Josef

“…We review recent progress on the similar biochemical characteristics and biological roles of the bioactive cyclopentenones, oxophytodienoic acid in plants and…”
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Vanadium in Asymmetric Synthesis: Emerging Concepts in Catalyst Design and Applications by Takizawa, Shinobu, Gröger, Harald, Sasai, Hiroaki

“…In recent years vanadium catalysis has been extended to a range of different and even complementary directions in asymmetric synthesis. Inspired by nature’s…”
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Front Cover: Shibasaki Catalysts and Their Use for Asymmetric Synthetic Applications by the Chemical Industry (Eur. J. Org. Chem. 24/2016) by Groger, Harald

“…The cover picture shows a range of chiral bifunctional catalysts developed by the group of Shibasaki. These catalysts are a unique, highly efficient, and…”
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Effect of Particle Wettability and Particle Concentration on the Enzymatic Dehydration of n‐Octanaloxime in Pickering Emulsions by Bago Rodriguez, Ana Maria, Schober, Lukas, Hinzmann, Alessa, Gröger, Harald, Binks, Bernard P.

“…Pickering emulsion systems have emerged as platforms for the synthesis of organic molecules in biphasic biocatalysis. Herein, the catalytic performance was…”
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Cyanide‐Free and Broadly Applicable Enantioselective Synthetic Platform for Chiral Nitriles through a Biocatalytic Approach by Betke, Tobias, Rommelmann, Philipp, Oike, Keiko, Asano, Yasuhisa, Gröger, Harald

“…A cyanide‐free platform technology for the synthesis of chiral nitriles by biocatalytic enantioselective dehydration of a wide range of aldoximes is reported…”
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Enzymatic Synthesis of Aliphatic Nitriles at a Substrate Loading of up to 1.4 kg/L: A Biocatalytic Record Achieved with a Heme Protein by Hinzmann, Alessa, Glinski, Sylvia, Worm, Marion, Gröger, Harald

“…A biocatalytic approach toward linear aliphatic nitriles being widely used as industrial bulk chemicals has been developed that runs at high substrate loadings…”
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Asymmetric Synthesis of 1‑Phenylethylamine from Styrene via Combined Wacker Oxidation and Enzymatic Reductive Amination by Uthoff, Florian, Gröger, Harald

“…An enantioselective chemoenzymatic two-step one-pot transformation of styrene to 1-phenylethylamine has been developed based on combining an initial…”
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Chemoenzymatic Cascades toward Aliphatic Nitriles Starting from Biorenewable Feedstocks by Hinzmann, Alessa, Stricker, Michael, Gröger, Harald

“…A modern concept of producing nitriles involves aldoxime dehydratases, which are capable of dehydrating aldoximes to the corresponding nitriles without need of…”
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Hydroxy Functionalization of Non-Activated CH and CC Bonds: New Perspectives for the Synthesis of Alcohols through Biocatalytic Processes by Groger, Harald

“…New perspectives through enzymes: Recent breakthroughs have been achieved in the selective hydroxy functionalization of non‐activated CH and CC bonds…”
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Process Development for the Sustainable and Economic Production of Biobased and Biodegradable High-Performance Lubricants by Guntermann, Alina, Koch, Luisa, Gröger, Harald

“…In this contribution, we present a process development for an easy, efficient, and sustainable synthesis of recently developed biobased and biodegradable…”
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Enantioselective Synthesis of Thiomorpholines through Biocatalytic Reduction of 3,6-Dihydro‑2H‑1,4-thiazines Using Imine Reductases by Nonnhoff, Jannis, Stammler, Hans-Georg, Gröger, Harald

“…In this work, an enantioselective biocatalytic synthesis of chiral thiomorpholines using imine reductases (IREDs) is described. As substrates, four prochiral…”
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Reconstitution of Myoglobin with Iron Porphycene Generates an Artificial Aldoxime Dehydratase with Expanded Catalytic Activities by Kato, Shunsuke, Abe, Miteki, Gröger, Harald, Hayashi, Takashi

“…Biocatalytic aldoxime dehydration is one of the most efficient methods used for the synthesis of nitriles under ambient reaction conditions without the use of…”
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Rationalizing the Unprecedented Stereochemistry of an Enzymatic Nitrile Synthesis through a Combined Computational and Experimental Approach by Yavuzer, Hilmi, Asano, Yasuhisa, Gröger, Harald

“…In this contribution, the unique and unprecedented stereochemical phenomenon of an aldoxime dehydratase‐catalyzed enantioselective dehydration of racemic E‐…”
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Combination of Asymmetric Organo- and Biocatalytic Reactions in Organic Media Using Immobilized Catalysts in Different Compartments by Heidlindemann, Marcel, Rulli, Giuseppe, Berkessel, Albrecht, Hummel, Werner, Gröger, Harald

“…A proof of concept for the combination of an asymmetric organocatalytic reaction with a biotransformation toward a “one-pot like” process for 1,3-diols based…”
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