Search Results - "Groft, Sarah Grace"
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Tpl2 Signaling Regulates Dendritic Cell Activation and Responding T Cell Differentiation Following Mycobacterium tuberculosis Infection
Published in The Journal of immunology (1950) (01-05-2021)“…Abstract Mycobacterium tuberculosis (Mtb) utilizes a number of immune evasion mechanisms in order to persist inside of host antigen-presenting cells. Dendritic…”
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Journal Article -
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TLR2-Tpl2-dependent ERK Signaling Drives Opposite IL-12 Regulation in Dendritic Cells and Macrophages
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract This study investigated responses to TLR2-driven ERK signaling in dendritic cells versus macrophages. TLR2 signaling was induced with Pam3Cys, and the…”
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Journal Article -
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Outcomes of ERK Signaling Differ in Macrophages and Dendritic Cells
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Stimulation of dendritic cells and macrophages by pathogen-related products activates a variety of immune responses. Pathogen-induced cell signaling…”
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Journal Article -
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Tpl2-Dependent Signaling Regulates Dendritic Cell Maturation and Immune Function
Published 01-01-2022“…Pattern recognition receptors (PRRs) such as toll-like receptors (TLRs) on macrophages and dendritic cells (DCs) play important roles in innate and adaptive…”
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Dissertation