Search Results - "Groeters, S."

Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma by Mattes, W., Davis, K., Fabian, E., Greenhaw, J., Herold, M., Looser, R., Mellert, W., Groeters, S., Marxfeld, H., Moeller, N., Montoya-Parra, G., Prokoudine, A., van Ravenzwaay, B., Strauss, V., Walk, T., Kamp, H.

“…While conventional parameters used to detect hepatotoxicity in drug safety assessment studies are generally informative, the need remains for parameters that…”
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Application of in vivo metabolomics to preclinical/toxicological studies: case study on phenytoin-induced systemic toxicity by Kamp, H, Fabian, E, Groeters, S, Herold, M, Krennrich, G, Looser, R, Mattes, W, Mellert, W, Prokoudine, A, Ruiz-Noppinger, P, Strauss, V, Walk, T, Wiemer, J, van Ravenzwaay, B

“…BASF and Metanomics have built-up the database MetaMap(®)-Tox containing rat plasma metabolome data for more than 500 reference compounds. Phenytoin was…”
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P09-11 Historical control data on pathology and neuropathology collected in OECD TG 443 or OECD TG 426 studies by Marxfeld, H., Melching-Kollmuss, S., Dammann, M., Stinchcombe, S., Gatto, V., Groeters, S.

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Non-cytocidal infection of keratinocytes by canine distemper virus in the so-called hard pad disease of canine distemper by Gröne, A., Groeters, S., Koutinas, A., Saridomichelakis, M., Baumgärtner, W.

“…A late, but not uncommon sequel to canine distemper virus (CDV) infection of dogs is thickening of footpads and nasal planum, the so-called hard pad disease,…”
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Safety assessment of [3S, 3′S]-astaxanthin – Subchronic toxicity study in rats by Buesen, R., Schulte, S., Strauss, V., Treumann, S., Becker, M., Gröters, S., Carvalho, S., van Ravenzwaay, B.

“…•Synthetic astaxanthin was investigated in a guideline conforming oral subchronic toxicity study in rats.•The examinations included clinical and…”
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Characterizing Adversity of Lysosomal Accumulation in Nonclinical Toxicity Studies: Results from the 5th ESTP International Expert Workshop by Lenz, B., Braendli-Baiocco, A., Engelhardt, J., Fant, P., Fischer, H., Francke, S., Fukuda, R., Gröters, S., Harada, T., Harleman, H., Kaufmann, W., Kustermann, S., Nolte, T., Palazzi, X., Pohlmeyer-Esch, G., Popp, A., Romeike, A., Schulte, A., Lima, B. Silva, Tomlinson, L., Willard, J., Wood, C. E., Yoshida, M.

“…Lysosomes have a central role in cellular catabolism, trafficking, and processing of foreign particles. Accumulation of endogenous and exogenous materials in…”
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Canine distemper virus--an agent looking for new hosts by Baumgärtner, W, Alldinger, S, Beineke, A, Gröters, S, Herden, C, Kaim, U, Müller, G, Seeliger, F, Van Moll, P, Wohlsein, P

“…Canine distemper is caused by the canine distemper virus (CDV), a RNA virus belonging to the genus Morbillivirus of the family Paramyxoviridae. The genus…”
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