Search Results - "Groenewold, G. J. Mirjam"
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Synthetic methodology towards allylic trans -cyclooctene-ethers enables modification of carbohydrates: bioorthogonal manipulation of the lac repressor
Published in Chemical science (Cambridge) (08-09-2020)“…The inverse electron-demand Diels-Alder (IEDDA) pyridazine elimination is one of the key bioorthogonal bond-breaking reactions. In this reaction -cyclooctene…”
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Methyltetrazine as a small live-cell compatible bioorthogonal handle for imaging enzyme activities in situ
Published in RSC chemical biology (02-11-2022)“…Bioorthogonal chemistry combines well with activity-based protein profiling, as it allows for the introduction of detection tags without significantly…”
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Bioorthogonal protein labelling enables the study of antigen processing of citrullinated and carbamylated auto-antigens
Published in RSC chemical biology (23-02-2021)“…Proteolysis is fundamental to many biological processes. In the immune system, it underpins the activation of the adaptive immune response: degradation of…”
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Methyltetrazine as a small live-cell compatible bioorthogonal handle for imaging enzyme activities
Published in RSC chemical biology (02-11-2022)“…Bioorthogonal chemistry combines well with activity-based protein profiling, as it allows for the introduction of detection tags without significantly…”
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Journal Article -
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Synthetic methodology towards allylic -cyclooctene-ethers enables modification of carbohydrates: bioorthogonal manipulation of the repressor
Published in Chemical science (Cambridge) (30-09-2020)“…The inverse electron-demand Diels-Alder (IEDDA) pyridazine elimination is one of the key bioorthogonal bond-breaking reactions. In this reaction trans…”
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Journal Article