Search Results - "Groenen, P."

EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected lymphoproliferations by Langerak, A W, Groenen, P J T A, Brüggemann, M, Beldjord, K, Bellan, C, Bonello, L, Boone, E, Carter, G I, Catherwood, M, Davi, F, Delfau-Larue, M-H, Diss, T, Evans, P A S, Gameiro, P, Garcia Sanz, R, Gonzalez, D, Grand, D, Håkansson, Å, Hummel, M, Liu, H, Lombardia, L, Macintyre, E A, Milner, B J, Montes-Moreno, S, Schuuring, E, Spaargaren, M, Hodges, E, van Dongen, J J M

“…PCR-based immunoglobulin (Ig)/T-cell receptor (TCR) clonality testing in suspected lymphoproliferations has largely been standardized and has consequently…”
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PAX5 P80R-mutated B-cell acute lymphoblastic leukemia with transformation to histiocytic sarcoma: clonal evolution assessment using NGS-based immunoglobulin clonality and mutation analysis by Kroeze, Leonie I., Scheijen, B., Hebeda, K. M., Rijntjes, J., Luijks, J. A. C. W., Evers, D., Hobo, W., Groenen, P. J. T. A., van den Brand, M.

“…Clonality assessment by the detection of immunoglobulin (IG) gene rearrangements is an important method to determine whether two concurrent or subsequent…”
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Serum IL‐5 and IL‐13 consistently serve as the best predictors for the blood eosinophilia phenotype in adult asthmatics by Agache, I., Strasser, D. S., Klenk, A., Agache, C., Farine, H., Ciobanu, C., Groenen, P. M. A., Akdis, C. A.

“…Background Molecular biomarkers that identify the phenotype of blood eosinophilia were evaluated in adult asthmatics, and their relationship with clinically…”
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Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-3936 by BRÜGGEMANN, M, WHITE, H, TIEMANN, M, HERBST, H, LANGERAK, A. W, SPAARGAREN, M, MOREAU, E, GROENEN, P. J. T. A, SAMBADE, C, FORONI, L, CARTER, G. I, HUMMEL, M, GAULARD, P, BASTARD, C, DAVI, F, DELFAU-LARUE, M.-H, KNEBA, M, VAN DONGEN, J. J. M, BELDJORD, K, MOLINA, Tj, GARCIA-SANZ, R, GAMEIRO, P, OESCHGER, S., JASANI, B, OTT, M, DELSOL, G, ORFAO, A

“…Polymerase chain reaction (PCR) assessment of clonal T-cell receptor (TCR) and immunoglobulin (Ig) gene rearrangements is an important diagnostic tool in…”
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Glucosylceramide synthase inhibition with lucerastat lowers globotriaosylceramide and lysosome staining in cultured fibroblasts from Fabry patients with different mutation types by Welford, R W D, Mühlemann, A, Garzotti, M, Rickert, V, Groenen, P M A, Morand, O, Üçeyler, N, Probst, M R

“…Abstract Fabry disease is an X-linked lysosomal storage disorder caused by mutations in the GLA gene coding for α-galactosidase A (α-GalA). The deleterious…”
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Clinicopathological characteristics and outcome of 31 patients with ETV6-NTRK3 fusion gene confirmed (mammary analogue) secretory carcinoma of salivary glands by Boon, E., Valstar, M.H., van der Graaf, W.T.A., Bloemena, E., Willems, S.M., Meeuwis, C.A., Slootweg, P.J., Smit, L.A., Merkx, M.A.W., Takes, R.P., Kaanders, J.H.A.M., Groenen, P.J.T.A., Flucke, U.E., van Herpen, C.M.L.

“…•We evaluated 31 patients with secretory carcinoma of salivary glands.•Clinical outcomes were generally good with 5- and 10-year overall survival of 95%.•One…”
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Significantly improved PCR-based clonality testing in B-cell malignancies by use of multiple immunoglobulin gene targets. Report of the BIOMED-2 Concerted Action BHM4-CT98-3936 by EVANS, P. A. S, POTT, Ch, SCHUURING, E, SPAARJAREN, M, BOONE, E, GONZALEZ, D, MARTINEZ, B, VILLUENDAS, R, GAMEIRO, P, DISS, T. C, MILLS, K, MORGAN, G. J, GROENEN, P. J. T. A, CARTER, G. I, MILNER, B. J, PEARSON, D, HUMMEL, M, JUNG, W, OTT, M, CANIONI, D, BELDJORD, K, BASTARD, C, DELFAU-LARUE, M. H, SALLES, G, VAN DONGEN, J. J. M, MOLINA, T. J, CABEYADAS, J, DAVI, F, BERGER, F, GARCIA, J. F, VAN KRIEKEN, J. H. J. M, PALS, S, KLUIN, Ph

“…Polymerase chain reaction (PCR) assessment of clonal immunoglobulin (Ig) and T-cell receptor (TCR) gene rearrangements is an important diagnostic tool in…”
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Steroid and G Protein Binding Characteristics of the Seatrout and Human Progestin Membrane Receptor α Subtypes and Their Evolutionary Origins by Thomas, Peter, Pang, Y, Dong, J, Groenen, P, Kelder, J, de Vlieg, J, Zhu, Y, Tubbs, C

“…A novel progestin receptor (mPR) with seven-transmembrane domains was recently discovered in spotted seatrout and homologous genes were identified in other…”
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Improved reliability of lymphoma diagnostics via PCR-based clonality testing: - Report of the BIOMED-2 Concerted Action BHM4-CT98-3936 by VAN KRIEKEN, J. H. J. M, LANGERAK, A. W, GAULARD, P, JASANI, B, GARCIA, J. F, OTT, M, HANNSMANN, M. L, BERGER, F, HUMMEL, M, DAVI, F, BRÜGGEMANN, M, LAVENDER, F. L, MACINTYRE, E. A, SCHUURING, E, EVANS, P. A. S, WHITE, H, SALLES, G, GROENEN, P. J. T. A, GAMEIRO, P, POTT, Ch, VAN DONGEN, J. J. M, KNEBA, M, HODGES, E, GARCIA SANZ, R, MORGAN, G. J, PARREIRA, A, MOLINA, T. J, CABECADAS, J

“…The diagnosis of malignant lymphoma is a recognized difficult area in histopathology. Therefore, detection of clonality in a suspected lymphoproliferation is a…”
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Independent development of lymphoid and histiocytic malignancies from a shared early precursor by Waanders, E, Hebeda, K M, Kamping, E J, Groenen, P J T A, Simons, A, Hoischen, A, Jongmans, M C J, Hoogerbrugge, P M, van Leeuwen, F N, Kuiper, R P, te Loo, D M W M

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Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis—a review by Löwik, M. M., Groenen, P. J., Levtchenko, E. N., Monnens, L. A., van den Heuvel, L. P.

“…This review deals with podocyte proteins that play a significant role in the structure and function of the glomerular filter. Genetic linkage studies has…”
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Focal segmental glomerulosclerosis in a patient homozygous for a CD2AP mutation by Löwik, M.M., Groenen, P.J.T.A., Pronk, I., Lilien, M.R., Goldschmeding, R., Dijkman, H.B., Levtchenko, E.N., Monnens, L.A., van den Heuvel, L.P.

“…Focal segmental glomerulosclerosis (FSGS) is a histologic diagnosis in several kidney diseases characterized by proteinuria and a severe decrease in kidney…”
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Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond by Rosenquist, Richard, Rosenwald, Andreas, Du, Ming-Qing, Gaidano, Gianluca, Groenen, Patricia, Wotherspoon, Andrew, Ghia, Paolo, Gaulard, Philippe, Campo, Elias, Stamatopoulos, Kostas

“…Similar to the inherent clinical heterogeneity of most, if not all, lymphoma entities, the genetic landscape of these tumors is markedly complex in the…”
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Prognostic significance of NAB2–STAT6 fusion variants and TERT promotor mutations in solitary fibrous tumors/hemangiopericytomas of the CNS: not (yet) clear by Vogels, Rob, Macagno, Nicolas, Griewank, Klaus, Groenen, Patricia, Verdijk, Marian, Fonville, Judy, Kusters, Benno, Figarella-Branger, Dominique, Wesseling, Pieter, Bouvier, Corinne, Flucke, Uta

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Bilateral vs. unilateral repetitive transcranial magnetic stimulation to treat neuropathic orofacial pain: A pilot study by Henssen, D.J.H.A., Hoefsloot, W., Groenen, P.S.M., Van Cappellen van Walsum, A.M., Kurt, E., Kozicz, T., van Dongen, R., Schutter, D.J.L.G., Bartels, R.H.M.A.

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Azathioprine and prednisone combination therapy in refractory coeliac disease by Goerres, M. S., Meijer, J. W. R., Wahab, P. J., Kerckhaert, J. A. M., Groenen, P. J. T. A., Van Krieken, J. H. J. M., Mulder, C. J. J.

“…Summary Introduction:  Refractory coeliac disease (RCD) is a rare syndrome with a poor prognosis, defined by malabsorption due to gluten‐related enteropathy…”
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Insulin-like growth factors and insulin-like growth factor-binding proteins in relation to disease status and incidence of hypoglycaemia in patients with a gastrointestinal stromal tumour by Rikhof, B., van Doorn, J., Suurmeijer, A.J.H., Rautenberg, M.W., Groenen, P.J.T.A., Verdijk, M.A.J., Jager, P.L., de Jong, S., Gietema, J.A., van der Graaf, W.T.A.

“…Patients with a gastrointestinal stromal tumour (GIST) suffering from non-islet cell tumour-induced hypoglycaemia (NICTH), being associated with increased…”
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Current Practices for DNA Sample Collection and Storage in the Pharmaceutical Industry, and Potential Areas for Harmonization: Perspective of the I-PWG by Franc, MA, Warner, AW, Cohen, N, Shaw, PM, Groenen, P, Snapir, A

“…Collection and storage of DNA samples in clinical drug development programs are an important investment for the pharmaceutical industry to allow efficient…”
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Area Biplots by Gower, J. C., Groenen, P. J. F., van de Velden, M.

“…Classical multivariate analysis techniques such as principal components analysis and correspondence analysis use inner products to approximate data values…”
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Coding of DNA Samples and Data in the Pharmaceutical Industry: Current Practices and Future Directions-Perspective of the I-PWG by Franc, MA, Cohen, N, Warner, AW, Shaw, PM, Groenen, P, Snapir, A

“…DNA samples collected in clinical trials and stored for future research are valuable to pharmaceutical drug development. Given the perceived higher risk…”
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