Search Results - "Grodzki, Cristina"

Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells by Proskocil, Becky J, Grodzki, Ana Cristina G, Jacoby, David B, Lein, Pamela J, Fryer, Allison D

“…Epidemiologic studies link organophosphorus pesticides (OPs) to increased incidence of asthma. In guinea pigs, OP-induced airway hyperreactivity requires…”
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Antibody purification: affinity chromatography - protein A and protein G Sepharose by Grodzki, Ana Cristina, Berenstein, Elsa

“…Affinity chromatography relies on the reversible interaction between a protein and a specific ligand immobilized in a chromatographic matrix. The sample is…”
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Oxygen tension modulates differentiation and primary macrophage functions in the human monocytic THP-1 cell line by Grodzki, Ana Cristina G, Giulivi, Cecilia, Lein, Pamela J

“…The human THP-1 cell line is widely used as an in vitro model system for studying macrophage differentiation and function. Conventional culture conditions for…”
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Antibody purification: ammonium sulfate fractionation or gel filtration by Grodzki, Ana Cristina, Berenstein, Elsa

“…Antibodies can be purified by a variety of methods based on their unique physical and chemical properties such as size, solubility, charge, hydrophobicity and…”
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Mis-trafficking of endosomal urokinase proteins triggers drug-induced glioma nonapoptotic cell death by Pasupuleti, Nagarekha, Grodzki, Ana Cristina, Gorin, Fredric

“…5-Benzylglycinyl-amiloride (UCD38B) is the parent molecule of a class of anticancer small molecules that kill proliferative and nonproliferative high-grade…”
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Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex by Stamou, Marianna, Grodzki, Ana Cristina, van Oostrum, Marc, Wollscheid, Bernd, Lein, Pamela J

“…Exposure of the developing brain to immune mediators, including antibodies, is postulated to increase risk for neurodevelopmental disorders and…”
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Identification and characterization of undifferentiated mast cells in mouse bone marrow by Jamur, Maria Célia, Grodzki, Ana Cristina G., Berenstein, Elsa H., Hamawy, Majed M., Siraganian, Reuben P., Oliver, Constance

“…Sequential immunomagnetic isolation with 2 monoclonal antibodies was used to purify and characterize an undifferentiated mast cell in adult mouse bone marrow…”
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Oxidized linoleic acid metabolites regulate neuronal morphogenesis in vitro by da Costa Souza, Felipe, Grodzki, Ana Cristina G., Morgan, Rhianna K., Zhang, Zhichao, Taha, Ameer Y., Lein, Pamela J.

“…Linoleic acid (LA, 18:2n-6) is an essential nutrient for optimal infant growth and brain development. The effects of LA in the brain are thought to be mediated…”
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Transient Stimulation with Psychoplastogens Is Sufficient to Initiate Neuronal Growth by Ly, Calvin, Greb, Alexandra C, Vargas, Maxemiliano V, Duim, Whitney C, Grodzki, Ana Cristina G, Lein, Pamela J, Olson, David E

“…Cortical neuron atrophy is a hallmark of depression and includes neurite retraction, dendritic spine loss, and decreased synaptic density. Psychoplastogens,…”
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Phospholipase D1 regulates high-affinity IgE receptor-induced mast cell degranulation by Hitomi, Tomohiro, Zhang, Juan, Nicoletti, Liliana M., Grodzki, Ana Cristina G., Jamur, Maria C., Oliver, Constance, Siraganian, Reuben P.

“…To investigate the role of phospholipase D (PLD) in FcϵRI signaling, the wild-type or the catalytically inactive forms of PLD1 or PLD2 were stably…”
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A novel carboline derivative inhibits nitric oxide formation in macrophages independent of effects on tumor necrosis factor α and interleukin-1β expression by Grodzki, Ana Cristina G, Poola, Bhaskar, Pasupuleti, Nagarekha, Nantz, Michael H, Lein, Pamela J, Gorin, Fredric

“…Neuropathic pain is a maladaptive immune response to peripheral nerve injury that causes a chronic painful condition refractory to most analgesics. Nitric…”
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Organophosphorus Pesticides Promote Cytokine Production in Human Macrophages by Grodzki, Cristina, Fryer, Allison, Lein, Pamela

“…Abstract only Macrophages are sentinel immune cells that reside in most if not all tissues and play a critical role in innate immunity. We previously…”
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FcɛRI-induced activation by low antigen concentrations results in nuclear signals in the absence of degranulation by Grodzki, Ana Cristina G., Moon, Kyungduk D., Berenstein, Elsa H., Siraganian, Reuben P.

“…High affinity IgE receptor (FcɛRI)-induced activation of mast cells results in degranulation and generation of leukotrienes and cytokines. FcɛRI-induced mast…”
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The low affinity IgG receptor FcγRIIB contributes to the binding of the mast cell specific antibody, mAb BGD6 by Guiraldelli, Michel F., Berenstein, Elsa H., Grodzki, Ana Cristina G., Siraganian, Reuben P., Jamur, Maria Celia, Oliver, Constance

“…The mast cell specific monoclonal antibody, mAb BGD6, is a mast cell lineage marker [Jamur, M.C., Grodzki, A.C., Berenstein, E.H., Hamawy, M.M., Siraganian,…”
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Mast cell repopulation of the peritoneal cavity: contribution of mast cell progenitors versus bone marrow derived committed mast cell precursors by Jamur, Maria Célia, Moreno, Andréa N, Mello, Luciana Fc, Souza Júnior, Devandir A, Campos, Maria Rita C, Pastor, Maria Verônica D, Grodzki, Ana Cristina G, Silva, Deise C, Oliver, Constance

“…Mast cells have recently gained new importance as immunoregulatory cells that are involved in numerous pathological processes. One result of these processes is…”
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IFNγ Increases M2 Muscarinic Receptor Expression in Cultured Sympathetic Neurons by Grodzki, Ana Cristina G, Ghogha, Atefeh, Mangini, Linley, Fryer, Allison D, Lein, Pamela J

“…M2 muscarinic receptors are expressed on both parasympathetic and sympathetic nerve endings where they function as autoinhibitory receptors to limit release of…”
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Developmental Exposure to Chlorpyrifos Modulates Pulmonary Function in Adult Rats by Grodzki, Ana Cristina, Schelegle, Edward, Lein, Pamela

“…Acute OP intoxication is well known to cause bronchoconstriction and increase airway secretions via inhibition of acetylcholinesterase (AChE). However,…”
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Mechanisms of organophosphorus pesticide toxicity in the context of airway hyperreactivity and asthma by Shaffo, Frances C, Grodzki, Ana Cristina, Fryer, Allison D, Lein, Pamela J

“…Numerous epidemiologic studies have identified an association between occupational exposures to organophosphorus pesticides (OPs) and asthma or asthmatic…”
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Effects of cytokines on nuclear factor-kappa B, cell viability, and synaptic connectivity in a human neuronal cell line by Matelski, Lauren, Morgan, Rhianna K., Grodzki, Ana Cristina, Van de Water, Judy, Lein, Pamela J.

“…Maternal infection during pregnancy is associated with increased risk of psychiatric and neurodevelopmental disorders (NDDs). Experimental animal models…”
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Identification of Psychoplastogenic N,N‑Dimethylaminoisotryptamine (isoDMT) Analogues through Structure–Activity Relationship Studies by Dunlap, Lee E, Azinfar, Arya, Ly, Calvin, Cameron, Lindsay P, Viswanathan, Jayashri, Tombari, Robert J, Myers-Turnbull, Douglas, Taylor, Jack C, Grodzki, Ana Cristina, Lein, Pamela J, Kokel, David, Olson, David E

“…Ketamine, N,N-dimethyltryptamine (DMT), and other psychoplastogens possess enormous potential as neurotherapeutics due to their ability to potently promote…”
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