Search Results - "Großmann, H."

Pioneers in Dermatology and Venereology: an interview with Prof. Dr. med. Hans‐Henning Grossmann by Grossmann, H.H.

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AKT1 Activation Promotes Development of Melanoma Metastases by Cho, Joseph H., Robinson, James P., Arave, Rowan A., Burnett, William J., Kircher, David A., Chen, Guo, Davies, Michael A., Grossmann, Allie H., VanBrocklin, Matthew W., McMahon, Martin, Holmen, Sheri L.

“…Metastases are the major cause of melanoma-related mortality. Previous studies implicating aberrant AKT signaling in human melanoma metastases led us to…”
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Interleukin receptor activates a MYD88–ARNO–ARF6 cascade to disrupt vascular stability by Zhu, Weiquan, London, Nyall R., Gibson, Christopher C., Davis, Chadwick T., Tong, Zongzhong, Sorensen, Lise K., Shi, Dallas S., Guo, Jinping, Smith, Matthew C. P., Grossmann, Allie H., Thomas, Kirk R., Li, Dean Y.

“…Interleukin-1β-induced disruption to endothelial stability and vascular permeability in a human in vitro model is shown to be independent of downstream nuclear…”
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Vapor Phase Exchange of Self-Assembled Monolayers for Engineering of Biofunctional Surfaces by Kankate, L, Aguf, A, Großmann, H, Schnietz, M, Tampé, R, Turchanin, A, Gölzhäuser, A

“…We show that 4′-nitro-1,1′-biphenyl-4-thiol self-assembled monolayers (NBPT SAMs) on gold can be exchanged with 11-(mercapto­undecyl)­triethylene glycol…”
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Tumour-intrinsic endomembrane trafficking by ARF6 shapes an immunosuppressive microenvironment that drives melanomagenesis and response to checkpoint blockade therapy by Wee, Yinshen, Wang, Junhua, Wilson, Emily C., Rich, Coulson P., Rogers, Aaron, Tong, Zongzhong, DeGroot, Evelyn, Gopal, Y. N. Vashisht, Davies, Michael A., Ekiz, H. Atakan, Tay, Joshua K. H., Stubben, Chris, Boucher, Kenneth M., Oviedo, Juan M., Fairfax, Keke C., Williams, Matthew A., Holmen, Sheri L., Wolff, Roger K., Grossmann, Allie H.

“…Tumour-host immune interactions lead to complex changes in the tumour microenvironment (TME), impacting progression, metastasis and response to therapy. While…”
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Application of extra-low impact energy SIMS and data reduction algorithm to USJ profiling by Kouzminov, D., Merkulov, A., Arevalo, E., Grossmann, H.-J.

“…Secondary ion mass spectrometry analysis of ultra‐shallow (sub‐200 eV) B implants is complicated by the presence of native oxide on the surface of Si…”
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Severe liver and skin toxicity after radiation and vemurafenib in metastatic melanoma by Anker, Christopher J, Ribas, Antoni, Grossmann, Allie H, Chen, Xinjian, Narra, Krishna K, Akerley, Wallace, Andtbacka, Robert H I, Noyes, Robert Dirk, Shrieve, Dennis C, Grossmann, Kenneth F

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Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice by Chan, Aubrey C, Drakos, Stavros G, Ruiz, Oscar E, Smith, Alexandra C H, Gibson, Christopher C, Ling, Jing, Passi, Samuel F, Stratman, Amber N, Sacharidou, Anastasia, Revelo, M Patricia, Grossmann, Allie H, Diakos, Nikolaos A, Davis, George E, Metzstein, Mark M, Whitehead, Kevin J, Li, Dean Y

“…Cerebral cavernous malformations (CCMs) are a common type of vascular malformation in the brain that are a major cause of hemorrhagic stroke. This condition…”
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25 years International Bladder Cancer Network (IBCN): The past, the present, and the future by Dyrskjøt, Lars, Vlahou, Antonia, Black, Peter C., Droller, Michael, Grossmann, H. Barton, Goebell, Peter J., Kamat, Ashish M., Nawroth, Roman, Seiler, Roland, Todenhöfer, Tilman, Williams, Stephen B., Schmitz-Dräger, Bernd J.

“…•The International Bladder Cancer Network (IBCN) is an interdisciplinary network.•The mission of the IBCN is to improve the management of bladder cancer using…”
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Molecular Self-Assembly, Chemical Lithography, and Biochemical Tweezers: A Path for the Fabrication of Functional Nanometer-Scale Protein Arrays by Turchanin, A., Tinazli, A., El-Desawy, M., Großmann, H., Schnietz, M., Solak, H. H., Tampé, R., Gölzhäuser, A.

“…Electron‐induced chemical lithography combined with self‐assembled monolayers and multivalent chelators for high‐affinity capturing of His‐tagged proteins are…”
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Detection of Gene Rearrangements in Targeted Clinical Next-Generation Sequencing by Abel, Haley J, Al-Kateb, Hussam, Cottrell, Catherine E, Bredemeyer, Andrew J, Pritchard, Colin C, Grossmann, Allie H, Wallander, Michelle L, Pfeifer, John D, Lockwood, Christina M, Duncavage, Eric J

“…The identification of recurrent gene rearrangements in the clinical laboratory is the cornerstone for risk stratification and treatment decisions in many…”
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Nanoscale mixing during double-flame spray synthesis of heterostructured nanoparticles by Grossmann, H. K., Grieb, T., Meierhofer, F., Hodapp, M. J., Noriler, D., Gröhn, A., Meier, H. F., Fritsching, U., Wegner, K., Mädler, L.

“…The combination of two nanoparticle-producing flame reactors to a double-flame (DF) spray pyrolysis process is an attractive method for the high-temperature…”
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AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis by Kircher, David A., Trombetti, Kirby A., Silvis, Mark R., Parkman, Gennie L., Fischer, Grant M., Angel, Stephanie N., Stehn, Christopher M., Strain, Sean C., Grossmann, Allie H., Duffy, Keith L., Boucher, Kenneth M., McMahon, Martin, Davies, Michael A., Mendoza, Michelle C., VanBrocklin, Matthew W., Holmen, Sheri L.

“…Abstract Alterations in the PI3K/AKT pathway occur in up to 70% of melanomas and are associated with disease progression. The three AKT paralogs are highly…”
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Dermatopathology in sub-Saharan Africa: a systematic 5-year analysis of all histopathological diagnoses from the Regional Dermatology Training Centre (RDTC) in Moshi, Tanzania by Beltraminelli, H., Kiprono, S., Zuriel, D., Swai, B., Giabbani, E., Grossmann, H., Masenga, J.E.

“…Background Proper diagnosis of skin diseases relies on dermatopathology, the most important diagnostic technique in dermatology. Unfortunately, there are few…”
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Double flame spray pyrolysis as a novel technique to synthesize alumina-supported cobalt Fischer–Tropsch catalysts by Minnermann, M., Grossmann, H.K., Pokhrel, S., Thiel, K., Hagelin-Weaver, H., Bäumer, M., Mädler, L.

“…•Co/Al2O3 Fischer–Tropsch (FT) catalysts were prepared by one-step single (SFSP) and double flame spray pyrolysis (DFSP).•SFSP catalysts were only FT active…”
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Classification, Molecular Characterization, and the Significance of Pten Alteration in Leiomyosarcoma by Grossmann, Allie H., Layfield, Lester J., Randall, R. Lor

“…Leiomyosarcoma is a malignant smooth muscle neoplasm with a complicated histopathologic classification scheme and marked differences in clinical behavior…”
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Molecular Confirmation of Ewing Sarcoma in an 85-Year-Old Woman by Monument, Michael J., Grossmann, Allie H., Baker, Christine C., Randall, R. Lor, Liu, Ting, Albertson, Daniel J.

“…We report a case of a Ewing sarcoma/primitive neuroectodermal tumor in an 85-year-old woman who presented with an enlarging circumscribed left flank mass…”
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ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma by Yoo, Jae Hyuk, Shi, Dallas S., Grossmann, Allie H., Sorensen, Lise K., Tong, ZongZhong, Mleynek, Tara M., Rogers, Aaron, Zhu, Weiquan, Richards, Jackson R., Winter, Jacob M., Zhu, Jie, Dunn, Christine, Bajji, Ashok, Shenderovich, Mark, Mueller, Alan L., Woodman, Scott E., Harbour, J. William, Thomas, Kirk R., Odelberg, Shannon J., Ostanin, Kirill, Li, Dean Y.

“…Activating mutations in Gαq proteins, which form the α subunit of certain heterotrimeric G proteins, drive uveal melanoma oncogenesis by triggering multiple…”
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Maternal Effect for DNA Mismatch Repair in the Mouse by Gurtu, Vanessa E, Verma, Shelly, Grossmann, Allie H, Liskay, R. Michael, Skarnes, William C, Baker, Sean M

“…DNA mismatch repair (DMR) functions to maintain genome stability. Prokaryotic and eukaryotic cells deficient in DMR show a microsatellite instability (MSI)…”
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Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation by Gibson, Christopher C, Zhu, Weiquan, Davis, Chadwick T, Bowman-Kirigin, Jay A, Chan, Aubrey C, Ling, Jing, Walker, Ashley E, Goitre, Luca, Delle Monache, Simona, Retta, Saverio Francesco, Shiu, Yan-Ting E, Grossmann, Allie H, Thomas, Kirk R, Donato, Anthony J, Lesniewski, Lisa A, Whitehead, Kevin J, Li, Dean Y

“…Cerebral cavernous malformation (CCM) is a hemorrhagic stroke disease affecting up to 0.5% of North Americans that has no approved nonsurgical treatment. A…”
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