Search Results - "Groß, W"

The foundations and development of lipidomics by Han, Xianlin, Gross, Richard W.

“…For over a century, the importance of lipid metabolism in biology was recognized but difficult to mechanistically understand due to the lack of sensitive and…”
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Diffusion tensor imaging in temporal lobe epilepsy by Gross, Donald W.

“…Summary Although mesial temporal sclerosis (MTS) has long been recognized in association with temporal lobe epilepsy (TLE), there is a growing body of…”
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Aberrant Schwann Cell Lipid Metabolism Linked to Mitochondrial Deficits Leads to Axon Degeneration and Neuropathy by Viader, Andreu, Sasaki, Yo, Kim, Sungsu, Strickland, Amy, Workman, Cayce S., Yang, Kui, Gross, Richard W., Milbrandt, Jeffrey

“…Mitochondrial dysfunction is a common cause of peripheral neuropathy. Much effort has been devoted to examining the role played by neuronal/axonal…”
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Network analysis for a network disorder: The emerging role of graph theory in the study of epilepsy by Bernhardt, Boris C, Bonilha, Leonardo, Gross, Donald W

“…Abstract Recent years have witnessed a paradigm shift in the study and conceptualization of epilepsy, which is increasingly understood as a network-level…”
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Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation by Li, Wenjun, Feng, Guoshuai, Gauthier, Jason M, Lokshina, Inessa, Higashikubo, Ryuji, Evans, Sarah, Liu, Xinping, Hassan, Adil, Tanaka, Satona, Cicka, Markus, Hsiao, Hsi-Min, Ruiz-Perez, Daniel, Bredemeyer, Andrea, Gross, Richard W, Mann, Douglas L, Tyurina, Yulia Y, Gelman, Andrew E, Kagan, Valerian E, Linkermann, Andreas, Lavine, Kory J, Kreisel, Daniel

“…Non-apoptotic forms of cell death can trigger sterile inflammation through the release of danger-associated molecular patterns, which are recognized by innate…”
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Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase I is essential for cancer cell proliferation independent of β-oxidation by Yao, Cong-Hui, Liu, Gao-Yuan, Wang, Rencheng, Moon, Sung Ho, Gross, Richard W, Patti, Gary J

“…It has been suggested that some cancer cells rely upon fatty acid oxidation (FAO) for energy. Here we show that when FAO was reduced approximately 90% by…”
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EULAR recommendations for the management of primary small and medium vessel vasculitis by Mukhtyar, C, Guillevin, L, Cid, M C, Dasgupta, B, de Groot, K, Gross, W, Hauser, T, Hellmich, B, Jayne, D, Kallenberg, C G M, Merkel, P A, Raspe, H, Salvarani, C, Scott, D G I, Stegeman, C, Watts, R, Westman, K, Witter, J, Yazici, H, Luqmani, R

“…To develop European League Against Rheumatism (EULAR) recommendations for the management of small and medium vessel vasculitis. An expert group (consisting of…”
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Mapping Anatomical Connectivity Patterns of Human Cerebral Cortex Using In Vivo Diffusion Tensor Imaging Tractography by Gong, Gaolang, He, Yong, Concha, Luis, Lebel, Catherine, Gross, Donald W., Evans, Alan C., Beaulieu, Christian

“…The characterization of the topological architecture of complex networks underlying the structural and functional organization of the brain is a basic…”
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2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides by Jennette, J. C., Falk, R. J., Bacon, P. A., Basu, N., Cid, M. C., Ferrario, F., Flores‐Suarez, L. F., Gross, W. L., Guillevin, L., Hagen, E. C., Hoffman, G. S., Jayne, D. R., Kallenberg, C. G. M., Lamprecht, P., Langford, C. A., Luqmani, R. A., Mahr, A. D., Matteson, E. L., Merkel, P. A., Ozen, S., Pusey, C. D., Rasmussen, N., Rees, A. J., Scott, D. G. I., Specks, U., Stone, J. H., Takahashi, K., Watts, R. A.

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EULAR recommendations for the management of large vessel vasculitis by Mukhtyar, C, Guillevin, L, Cid, M C, Dasgupta, B, de Groot, K, Gross, W, Hauser, T, Hellmich, B, Jayne, D, Kallenberg, C G M, Merkel, P A, Raspe, H, Salvarani, C, Scott, D G I, Stegeman, C, Watts, R, Westman, K, Witter, J, Yazici, H, Luqmani, R

“…To develop European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis. An expert group (10 rheumatologists, 3…”
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Shotgun lipidomics: Electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples by Han, Xianlin, Gross, Richard W.

“…Lipidomics, after genomics and proteomics, is a newly and rapidly expanding research field that studies cellular lipidomes and the organizational hierarchy of…”
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Automated Lipid Identification and Quantification by Multidimensional Mass Spectrometry-Based Shotgun Lipidomics by Yang, Kui, Cheng, Hua, Gross, Richard W, Han, Xianlin

“…This article presents the strategies underlying the automated identification and quantification of individual lipid molecular species through array analysis of…”
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Identification and Quantitation of Fatty Acid Double Bond Positional Isomers: A Shotgun Lipidomics Approach Using Charge-Switch Derivatization by Yang, Kui, Dilthey, Beverly Gibson, Gross, Richard W.

“…The specific locations of double bonds in mammalian lipids have profound effects on biological membrane structure, dynamics and lipid second messenger…”
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Exogenous Fatty Acids Are the Preferred Source of Membrane Lipids in Proliferating Fibroblasts by Yao, Cong-Hui, Fowle-Grider, Ronald, Mahieu, Nathanial G, Liu, Gao-Yuan, Chen, Ying-Jr, Wang, Rencheng, Singh, Manmilan, Potter, Gregory S, Gross, Richard W, Schaefer, Jacob, Johnson, Stephen L, Patti, Gary J

“…Cellular proliferation requires the formation of new membranes. It is often assumed that the lipids needed for these membranes are synthesized mostly de novo…”
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Metabolic regulator LKB1 is crucial for Schwann cell–mediated axon maintenance by Beirowski, Bogdan, Babetto, Elisabetta, Golden, Judith P, Chen, Ying-Jr, Yang, Kui, Gross, Richard W, Patti, Gary J, Milbrandt, Jeffrey

“…Axonal maintenance is known to rely, in part, on non-cell-autonomous support from myelinating glia, but the mechanisms are still unclear. In this study, the…”
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Environmental exposure enhances the internalization of microplastic particles into cells by Ramsperger, A F R M, Narayana, V K B, Gross, W, Mohanraj, J, Thelakkat, M, Greiner, A, Schmalz, H, Kress, H, Laforsch, C

“…Microplastic particles ubiquitously found in the environment are ingested by a huge variety of organisms. Subsequently, microplastic particles can translocate…”
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Outcomes from studies of antineutrophil cytoplasm antibody associated vasculitis: a systematic review by the European League Against Rheumatism systemic vasculitis task force by Mukhtyar, C, Flossmann, O, Hellmich, B, Bacon, P, Cid, M, Cohen-Tervaert, J W, Gross, W L, Guillevin, L, Jayne, D, Mahr, A, Merkel, P A, Raspe, H, Scott, D, Witter, J, Yazici, H, Luqmani, R A

“…We undertook a systematic literature review as a background to the European League Against Rheumatism (EULAR) recommendations for conducting clinical trials in…”
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Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics by Han, Xianlin, Gross, Richard W

“…Lipidomics is a rapidly expanding research field in which multiple techniques are utilized to quantitate the hundreds of chemically distinct lipids in cells…”
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Disrupted anatomic white matter network in left mesial temporal lobe epilepsy by Liu, Min, Chen, Zhang, Beaulieu, Christian, Gross, Donald W.

“…Summary Objective Brain imaging studies have shown widespread structural abnormalities in patients with temporal lobe epilepsy (TLE) within and beyond the…”
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The structure of iPLA2β reveals dimeric active sites and suggests mechanisms of regulation and localization by Malley, Konstantin R., Koroleva, Olga, Miller, Ian, Sanishvili, Ruslan, Jenkins, Christopher M., Gross, Richard W., Korolev, Sergey

“…Calcium-independent phospholipase A 2 β (iPLA 2 β) regulates important physiological processes including inflammation, calcium homeostasis and apoptosis. It is…”
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