Search Results - "Grmai, Lydia"

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  1. 1

    Integrated stress response signaling acts as a metabolic sensor in fat tissues to regulate oocyte maturation and ovulation by Grmai, Lydia, Michaca, Manuel, Lackner, Emily, Nampoothiri V.P., Narayanan, Vasudevan, Deepika

    Published in Cell reports (Cambridge) (26-03-2024)
    “…Reproduction is an energy-intensive process requiring systemic coordination. However, the inter-organ signaling mechanisms that relay nutrient status to…”
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    Journal Article
  2. 2

    Chinmo prevents transformer alternative splicing to maintain male sex identity by Grmai, Lydia, Hudry, Bruno, Miguel-Aliaga, Irene, Bach, Erika A

    Published in PLoS genetics (01-02-2018)
    “…Reproduction in sexually dimorphic animals relies on successful gamete production, executed by the germline and aided by somatic support cells. Somatic sex…”
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    Journal Article
  3. 3

    Transcriptomic analysis of feminizing somatic stem cells in the Drosophila testis reveals putative downstream effectors of the transcription factor Chinmo by Grmai, Lydia, Harsh, Sneh, Lu, Sean, Korman, Aryeh, Deb, Ishan B, Bach, Erika A

    Published in G3 : genes - genomes - genetics (15-04-2021)
    “…One of the best examples of sexual dimorphism is the development and function of the gonads, ovaries and testes, which produce sex-specific gametes, oocytes,…”
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    Journal Article
  4. 4

    Proteomic Pathway Analysis Reveals Inflammation Increases Myeloid-Derived Suppressor Cell Resistance to Apoptosis by Chornoguz, Olesya, Grmai, Lydia, Sinha, Pratima, Artemenko, Konstantin A., Zubarev, Roman A., Ostrand-Rosenberg, Suzanne

    Published in Molecular & cellular proteomics (01-03-2011)
    “…Myeloid-derived suppressor cells (MDSC) accumulate in patients and animals with cancer where they mediate systemic immune suppression and obstruct immune-based…”
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    Journal Article
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  7. 7

    Proliferative stem cells maintain quiescence of their niche by secreting the Activin inhibitor Follistatin by Herrera, Salvador C., Sainz de la Maza, Diego, Grmai, Lydia, Margolis, Shally, Plessel, Rebecca, Burel, Michael, O’Connor, Michael, Amoyel, Marc, Bach, Erika A.

    Published in Developmental cell (23-08-2021)
    “…Aging causes stem cell dysfunction as a result of extrinsic and intrinsic changes. Decreased function of the stem cell niche is an important contributor to…”
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    Journal Article
  8. 8

    The Role of Chinmo in Somatic Stem Cell Maintenance in the Drosophila Testis by Grmai, Lydia

    Published 01-01-2018
    “…Sexual dimorphism, a defining feature of nearly all eukaryotes, is the collection of differences between male and female individuals in a species. While…”
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    Dissertation
  9. 9

    An unassigned DAHP synthase activity found only in pathogenic Escherichia coli strains by Yep, Alejandra, Grmai, Lydia, Emanuele, Anthony A., Woodard, Ronald W.

    Published in The FASEB journal (01-04-2011)
    “…The enzyme 3‐deoxy‐D‐arabino‐heptulosonate 7‐phosphate synthase (DAHPS) catalyzes the first step of the shikimate biosynthetic pathway, which leads to the…”
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    Journal Article
  10. 10

    MHC II-restricted peptides derived from invariant chain negative breast cancer cell-based vaccines activate healthy donor T-cells (156.17) by Chornoguz, Olesya, Grmai, Lydia, Gapeev, Alexei, O’Neill, Michael, Ostrand-Rosenberg, Suzanne

    Published in The Journal of immunology (1950) (01-04-2011)
    “…Abstract We have generated cell-based MHC II vaccines to activate patients’ CD4+ T-cell to facilitate tumor immunity. This was based on the hypothesis that…”
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    Journal Article
  11. 11

    Regulation of proliferation, cell competition, and cellular growth by the Drosophila JAK-STAT pathway by Zoranovic, Tamara, Grmai, Lydia, Bach, Erika A

    Published in JAK-STAT (15-07-2013)
    “…The JAK-STAT pathway is a key regulator of tissue size in Drosophila melanogaster. Here we provide an overview of its roles in processes that regulate the size…”
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    Journal Article