Search Results - "Grmai, Lydia"
-
1
Integrated stress response signaling acts as a metabolic sensor in fat tissues to regulate oocyte maturation and ovulation
Published in Cell reports (Cambridge) (26-03-2024)“…Reproduction is an energy-intensive process requiring systemic coordination. However, the inter-organ signaling mechanisms that relay nutrient status to…”
Get full text
Journal Article -
2
Chinmo prevents transformer alternative splicing to maintain male sex identity
Published in PLoS genetics (01-02-2018)“…Reproduction in sexually dimorphic animals relies on successful gamete production, executed by the germline and aided by somatic support cells. Somatic sex…”
Get full text
Journal Article -
3
Transcriptomic analysis of feminizing somatic stem cells in the Drosophila testis reveals putative downstream effectors of the transcription factor Chinmo
Published in G3 : genes - genomes - genetics (15-04-2021)“…One of the best examples of sexual dimorphism is the development and function of the gonads, ovaries and testes, which produce sex-specific gametes, oocytes,…”
Get full text
Journal Article -
4
Proteomic Pathway Analysis Reveals Inflammation Increases Myeloid-Derived Suppressor Cell Resistance to Apoptosis
Published in Molecular & cellular proteomics (01-03-2011)“…Myeloid-derived suppressor cells (MDSC) accumulate in patients and animals with cancer where they mediate systemic immune suppression and obstruct immune-based…”
Get full text
Journal Article -
5
A ‘citizen science’ approach to transforming scientific research and education
Published in Developmental biology (01-09-2023)Get full text
Journal Article -
6
From motor neurons to Malta – A graduate student profile
Published in Developmental biology (01-04-2023)Get full text
Journal Article -
7
Proliferative stem cells maintain quiescence of their niche by secreting the Activin inhibitor Follistatin
Published in Developmental cell (23-08-2021)“…Aging causes stem cell dysfunction as a result of extrinsic and intrinsic changes. Decreased function of the stem cell niche is an important contributor to…”
Get full text
Journal Article -
8
The Role of Chinmo in Somatic Stem Cell Maintenance in the Drosophila Testis
Published 01-01-2018“…Sexual dimorphism, a defining feature of nearly all eukaryotes, is the collection of differences between male and female individuals in a species. While…”
Get full text
Dissertation -
9
An unassigned DAHP synthase activity found only in pathogenic Escherichia coli strains
Published in The FASEB journal (01-04-2011)“…The enzyme 3‐deoxy‐D‐arabino‐heptulosonate 7‐phosphate synthase (DAHPS) catalyzes the first step of the shikimate biosynthetic pathway, which leads to the…”
Get full text
Journal Article -
10
MHC II-restricted peptides derived from invariant chain negative breast cancer cell-based vaccines activate healthy donor T-cells (156.17)
Published in The Journal of immunology (1950) (01-04-2011)“…Abstract We have generated cell-based MHC II vaccines to activate patients’ CD4+ T-cell to facilitate tumor immunity. This was based on the hypothesis that…”
Get full text
Journal Article -
11
Regulation of proliferation, cell competition, and cellular growth by the Drosophila JAK-STAT pathway
Published in JAK-STAT (15-07-2013)“…The JAK-STAT pathway is a key regulator of tissue size in Drosophila melanogaster. Here we provide an overview of its roles in processes that regulate the size…”
Get full text
Journal Article