Search Results - "Grivell, Les"

The Mitochondrial Prohibitin Complex Is Essential for Embryonic Viability and Germline Function in Caenorhabditis elegans by Sanz, Marta Artal, Tsang, William Y., Willems, Esther M., Grivell, Les A., Lemire, Bernard D., van der Spek, Hans, Nijtmans, Leo G.J.

“…Prohibitins in eukaryotes consist of two subunits (PHB1 and PHB2) that together form a high molecular weight complex in the mitochondrial inner membrane. The…”
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Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins by Nijtmans, Leo G.J., de Jong, Liesbeth, Artal Sanz, Marta, Coates, Philip J., Berden, Jan A., Back, Jaap Willem, Muijsers, Anton O., van der Spek, Hans, Grivell, Les A.

“…Prohibitins are ubiquitous, abundant and evolutionarily strongly conserved proteins that play a role in important cellular processes. Using blue native…”
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Text mining for biology--the way forward: opinions from leading scientists by Altman, Russ B, Bergman, Casey M, Blake, Judith, Blaschke, Christian, Cohen, Aaron, Gannon, Frank, Grivell, Les, Hahn, Udo, Hersh, William, Hirschman, Lynette, Jensen, Lars Juhl, Krallinger, Martin, Mons, Barend, O'Donoghue, Seán I, Peitsch, Manuel C, Rebholz-Schuhmann, Dietrich, Shatkay, Hagit, Valencia, Alfonso

“…This article collects opinions from leading scientists about how text mining can provide better access to the biological literature, how the scientific…”
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A structure for the yeast prohibitin complex: Structure prediction and evidence from chemical crosslinking and mass spectrometry by Back, Jaap W., Sanz, Marta Artal, de Jong, Luitzen, de Koning, Leo J., Nijtmans, Leo G.J., de Koster, Chris G., Grivell, Les A., van der Spek, Hans, Muijsers, Anton O.

“…The mitochondrial prohibitin complex consists of two subunits (PHB1 of 32 kD and PHB2 of 34 kD), assembled into a membrane‐associated supercomplex of…”
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Hap4p overexpression in glucose-grown Saccharomyces cerevisiae induces cells to enter a novel metabolic state by Lascaris, Romeo, Bussemaker, Harmen J, Boorsma, André, Piper, Matt, van der Spek, Hans, Grivell, Les, Blom, Jolanda

“…Metabolic and regulatory gene networks generally tend to be stable. However, we have recently shown that overexpression of the transcriptional activator Hap4p…”
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Mitochondrial assembly in yeast by Grivell, Les A, Artal-Sanz, Marta, Hakkaart, Gertjan, de Jong, Liesbeth, Nijtmans, Leo G.J, van Oosterum, Katinka, Siep, Michel, van der Spek, Hans

“…The yeast Saccharomyces cerevisiae is likely to be the first organism for which a complete inventory of mitochondrial proteins and their functions can be drawn…”
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Through a glass darkly: The present and the future of editorial peer review by Grivell, Les

“…In conjunction with other changes in the world of scientific publishing, peer review the process and its goals has come under increased scrutiny and there are…”
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Mining the bibliome: searching for a needle in a haystack? by Grivell, Les

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The Yeast Mitochondrial Degradosome by Dziembowski, Andrzej, Piwowarski, Jan, Hoser, Rafal, Minczuk, Michal, Dmochowska, Aleksandra, Siep, Michel, van der Spek, Hans, Grivell, Les, Stepien, Piotr P.

“…The yeast mitochondrial degradosome (mtEXO) is an NTP-dependent exoribonuclease involved in mitochondrial RNA metabolism. Previous purifications suggested that…”
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Through a glass darkly by Grivell, Les

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EMBO Molecular Medicine—Where molecular biology meets clinical research by Bujard, Hermann, Grivell, Les

“…« Almost 60 years ago Linus Pauling coined the term ‘molecular disease’ based on the classical studies, which link the molecular structure of haemoglobin with…”
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Access for all?: While initiatives for self‐archiving and creating new open access journals gain momentum, new questions about the legal and economic basis of scientific publishing arise by Grivell, Les

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Seek and you shall find? by Grivell, Les

“…Search engines are increasingly important tools for browsing the vast spaces of the Internet. How good are they for searching through scientific literature?…”
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Mining the bibliome: searching for a needle in a haystack? New computing tools are needed to effectively scan the growing amount of scientific literature for useful information by Grivell, Les

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Defective Remodeling of Cardiolipin and Phosphatidylglycerol in Barth Syndrome by Vreken, Peter, Valianpour, Fredoen, Nijtmans, Leo G., Grivell, Les A., Plecko, Barbara, Wanders, Ronald J.A., Barth, Peter G.

“…Cardiolipin (CL) and phosphatidylglycerol (PG) are the major polyglycerophospholipids observed in mammalian tissues. CL is exclusively found in the inner…”
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Access for all? by Grivell, Les

“…While initiatives for self-archiving and creating new open access journals gain momentum, new questions about the legal and economic basis of scientific…”
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The yeast mitochondrial degradosome. Its composition, interplay between RNA helicase and RNase activities and the role in mitochondrial RNA metabolism by Dziembowski, Andrzej, Piwowarski, Jan, Hoser, Rafal, Minczuk, Michal, Dmochowska, Aleksandra, Siep, Michel, van der Spek, Hans, Grivell, Les, Stepien, Piotr P

“…The yeast mitochondrial degradosome (mtEXO) is an NTP-dependent exoribonuclease involved in mitochondrial RNA metabolism. Previous purifications suggested that…”
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E-BioSci by Grivell, Les

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Overexpression of HAP4 in glucose-derepressed yeast cells reveals respiratory control of glucose-regulated genes by Lascaris, Romeo, Piwowarski, Jan, van der Spek, Hans, de Mattos, Joost Teixeira, Grivell, Les, Blom, Jolanda

“…Swammerdam Institute for Life Sciences, University of Amsterdam, Kruislaan 318, 1098 SM Amsterdam, The Netherlands Correspondence Joost Teixeira de Mattos…”
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Carbon source-dependent transcriptional regulation of the QCR8 gene in Kluyveromyces lactis by Brons, Janynke, Agnieszka, Dryla, Plüger, Esther, Vinkenvleugel, Thessa, Hornig, Nadine, Grivell, Les, Blom, Jolanda

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