Educational simulation of the electroencephalogram (EEG)

Educational simulation of the electroencephalogram (EEG)

We describe a model for simulating a spontaneous electroencephalogram (EEG) and for simulating the effects of anesthesia on the EEG, to allow anesthesiologists and EEG technicians to learn and practice intraoperative EEG monitoring. For this purpose, we developed a linear model to manipulate the amp...

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Bibliographic Details
Published in:Technology and health care Vol. 9; no. 3; p. 237
Main Authors: de Beer, N A, van Meurs, W L, Grit, M B, Good, M L, Gravenstein, D
Format: Journal Article
Language:English
Published: Netherlands 2001
Subjects:
Anesthesiology - education
Anesthesiology - manpower
Anesthetics - administration & dosage
Anesthetics - pharmacokinetics
Anesthetics - pharmacology
Computer Simulation
Education, Medical - methods
Electroencephalography - drug effects
Electroencephalography - methods
Feasibility Studies
Humans
Intraoperative Care
Isoflurane - administration & dosage
Isoflurane - pharmacokinetics
Isoflurane - pharmacology
Linear Models
Thiopental - administration & dosage
Thiopental - pharmacokinetics
Thiopental - pharmacology
United States
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Summary:We describe a model for simulating a spontaneous electroencephalogram (EEG) and for simulating the effects of anesthesia on the EEG, to allow anesthesiologists and EEG technicians to learn and practice intraoperative EEG monitoring. For this purpose, we developed a linear model to manipulate the amplitude of the activity in each of the traditional EEG frequency bands. Burst suppression patterns are simulated by manipulating an overall gain. To demonstrate the model feasibility, model parameters for thiopental and isoflurane were estimated guided by published data on the EEG effects of these anesthetic drugs. Using these estimates, EEG time signals were simulated for isoflurane at various partial pressures, and for bolus intravenous doses of thiopental. Comparison with actual recorded EEG signals showed that the changes produced by isoflurane and thiopental in the simulated signals are very similar to the changes in the actual signals, which was confirmed by two clinicians with experience and routine practice in intraoperative EEG monitoring.
ISSN:0928-7329
DOI:10.3233/thc-2001-9302