Search Results - "Grishina, Elena A"
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Using the CYP3A Activity Evaluation to Predict the Efficacy and Safety of Diazepam in Patients With Alcohol Withdrawal Syndrome
Published in Journal of pharmacy practice (01-08-2022)“…Background: Diazepam is one of the most commonly prescribed tranquilizers for the therapy of alcohol withdrawal syndrome (AWS). Despite its popularity, there…”
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Effects of CYP2C192 polymorphisms on the efficacy and safety of phenazepam in patients with anxiety disorder and comorbid alcohol use disorder
Published in Pharmacogenomics (2020)“…© 2020 Future Science Group. Introduction: Phenazepam therapy can often be ineffective and some patients develop dose-related adverse drug reactions. Aim. The…”
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Role of Inflammatory Mediators, Growth Factors, and Osteodystrophy in Recurrent Lumbar Disk Herniation
Published in Annaly kliničeskoj i èksperimentalʹnoj nevrologii (Online) (21-06-2023)“…Introduction. Reintervention in patients with spinal disk herniation is shown to significantly decrease likelihood of favorable outcomes in the postoperative…”
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Using a personalized clinical decision support system for bromdihydrochlorphenylbenzodiazepine dosing in patients with anxiety disorders based on the pharmacogenomic markers
Published in Human psychopharmacology (01-11-2018)“…Introduction Although pharmacogenetic tests provide the information on a genotype and the predicted phenotype, these tests themselves do not provide the…”
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Evaluation of the association of polymorphisms of the CYP2C8 gene with the efficacy and safety of ketorolac in patients with postoperative pain syndrome
Published in Terapevtic̆eskii arhiv (17-06-2022)“…Aim. To evaluate the possible association of CYP2C8 gene polymorphisms with the clinical efficacy and safety of ketorolac in relation to postoperative pain…”
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CYP2C8, PTGS-1, 2 gene polymorphisms prevalence associated with sensitivity to non-steroidal anti-inflammatory drugs among North Caucasus ethnic groups
Published in Terapevtic̆eskii arhiv (15-11-2021)“…Aim. Find the prevalence of CYP2C8*3 (rs10509681; rs11572080), PTGS-1 (rs10306135; rs12353214) and PTGS-2 (rs20417) alleles and genotypes in four ethnic groups…”
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Antihypertensive Effect Of Amlodipine In Co-Administration With Omeprazole In Patients With Hypertension And Acid-Related Disorders: Cytochrome P450-Associated Aspects
Published in Pharmacogenomics and personalized medicine (01-01-2019)“…CYP2C19 and CYP3A are the main enzymes involved in omeprazole metabolism, while CYP3A is the principal enzyme family for amlodipine biotransformation…”
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CYP3A and CYP2C19 activity in urine in relation to CYP3A4, CYP3A5, and CYP2C19 polymorphisms in Russian peptic ulcer patients taking omeprazole
Published in Pharmacogenomics and personalized medicine (01-01-2018)“…Proton pump inhibitors (PPIs) are metabolized by cytochrome P450. CYP2C19 is the main isoenzyme for the majority of PPI, whereas CYP3A family is a secondary…”
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Urine metabolic ratio of omeprazole in relation to CYP2C19 polymorphisms in Russian peptic ulcer patients
Published in Pharmacogenomics and personalized medicine (01-01-2017)“…CYP2C19 is known to be the main enzyme of biotransformation of proton pump inhibitors (PPIs), whereas the gene is highly polymorphic. Genotyping and…”
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Do CYP2C19 and ABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients?
Published in Pharmacogenomics and personalized medicine (01-01-2017)“…The aim of this study was to determine the impact of and gene polymorphisms and CYP3A4 isoenzyme activity on stent implantation complications among patients…”
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EJECTION PRESSURE LOCK CHARACTERISTICS AND CALCULATION
Published in Vestnik Donskogo gosudarstvennogo tehničeskogo universiteta (Online) (01-07-2018)“…A design model and general properties of the ejection pressure lock are offered. A selection method of the pressure lock with the lowest power consumption is…”
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Hyperbaric Oxygenation in Recurrent Rectal Bleeding in the Background of Radiation Proctitis
Published in Neotložnaâ Medicinskaâ Pomoŝʹ (09-04-2022)“…Radiation proctitis is a complication of radiation therapy used in the treatment of pelvic malignant tumors. The leading clinical symptom of this kind of late…”
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Polymorphism 3435c> t of the ABCB1 gene (rs1045642) does not affect the mirtazapine efficiency and safety profile in patients with depressive disorders comorbid with alcohol use disorder
Published in Bi͡u︡lletenʹ Sibirskoĭ medit͡s︡iny (07-01-2021)“…Background. Mirtazapine is used to treat patients with depressive disorders. A large proportion of patients in this group do not adequately respond to…”
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Effects of CYP2D6 genetic polymorphisms on the efficacy and safety of fluvoxamine in patients with depressive disorder and comorbid alcohol use disorder
Published in Pharmacogenomics and personalized medicine (01-01-2018)“…Fluvoxamine therapy is used for treatment of patients with depressive disorder, but it is often ineffective, and some patients suffer from dose-dependent…”
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Effect of polymorphisms in CYP3A422 (rs35599367) C>T, CYP3A53 (rs776746) A>G, ABCB1 (rs4148738) C>T and ABCB1 (rs1045642) C>T genes on apixaban anticoagulation: pilot study results
Published in Medicinskij sovet (20-04-2021)“…Introduction . Apixaban is a direct oral anticoagulant prescribed for treatment and prevention of venous thromboembolism (VTE) and for prevention of stroke in…”
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Do CYP2C 19 and ABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients?
Published in Pharmacogenomics and personalized medicine (01-01-2017)“…Aim: The aim of this study was to determine the impact of CYP2C19 and ABCB1 gene polymorphisms and CYP3A4 isoenzyme activity on stent implantation…”
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Urine metabolic ratio of omeprazole in relation to CYP2C 19 polymorphisms in Russian peptic ulcer patients
Published in Pharmacogenomics and personalized medicine (01-01-2017)“…Background: CYP2C 19 is known to be the main enzyme of biotransformation of proton pump inhibitors (PPIs), whereas the CYP2C19 gene is highly polymorphic…”
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Do CYP2C19 andABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients?
Published in Pharmacogenomics and personalized medicine (01-01-2017)“…Aim: The aim of this study was to determine the impact of CYP2C19 and ABCB1gene polymorphisms and CYP3A4 isoenzyme activity on stent implantation complications…”
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New Pharmacogenetic Markers to Predict the Risk of Bleeding During Taking of Direct Oral Anticoagulants
Published in Rat͡s︡ionalʹnai͡a︡ farmakoterapii͡a︡ v kardiologii (04-11-2020)“…Aim . To search for new pharmacogenetic biomarkers of bleeding risk in patients taking rivaroxaban and dabigatran for different indications: atrial…”
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